Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | family S28 unassigned peptidase (S28 family) | 0.4536 | 0.4752 | 0.4752 |
Echinococcus granulosus | dipeptidyl aminopeptidaseprotein | 0.8546 | 1 | 1 |
Giardia lamblia | Alanyl dipeptidyl peptidase | 0.0904 | 0 | 0.5 |
Trichomonas vaginalis | Clan SC, family S9, acylaminoacyl-peptidase-like serine peptidase | 0.0904 | 0 | 0.5 |
Echinococcus granulosus | Dipeptidyl peptidase 9 | 0.5223 | 0.5651 | 0.5651 |
Loa Loa (eye worm) | hypothetical protein | 0.2291 | 0.1814 | 0.1814 |
Entamoeba histolytica | dipeptidyl-peptidase, putative | 0.0904 | 0 | 0.5 |
Mycobacterium tuberculosis | Probable protease II PtrBb [second part] (oligopeptidase B) | 0.0904 | 0 | 0.5 |
Echinococcus granulosus | Lysosomal Pro X carboxypeptidase | 0.4536 | 0.4752 | 0.4752 |
Brugia malayi | hypothetical protein | 0.2932 | 0.2653 | 0.2653 |
Entamoeba histolytica | prolyl oligopeptidase family protein | 0.0904 | 0 | 0.5 |
Echinococcus multilocularis | Lysosomal Pro X carboxypeptidase | 0.4536 | 0.4752 | 0.4752 |
Leishmania major | dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B | 0.5223 | 0.5651 | 1 |
Schistosoma mansoni | subfamily S9B unassigned peptidase (S09 family) | 0.8546 | 1 | 1 |
Entamoeba histolytica | prolyl oligopeptidase family protein | 0.0904 | 0 | 0.5 |
Mycobacterium ulcerans | protease II (oligopeptidase B), PtrB | 0.0904 | 0 | 0.5 |
Mycobacterium tuberculosis | Probable peptidase | 0.0904 | 0 | 0.5 |
Echinococcus multilocularis | dipeptidyl aminopeptidaseprotein | 0.8546 | 1 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0904 | 0 | 0.5 |
Schistosoma mansoni | dipeptidyl-peptidase 9 (S09 family) | 0.5223 | 0.5651 | 0.5651 |
Loa Loa (eye worm) | prolyl oligopeptidase | 0.8546 | 1 | 1 |
Trypanosoma cruzi | dipeptidyl-peptidase 8-like serine peptidase | 0.5223 | 0.5651 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.2932 | 0.2653 | 0.2653 |
Entamoeba histolytica | prolyl oligopeptidase family protein | 0.0904 | 0 | 0.5 |
Entamoeba histolytica | dipeptidyl-peptidase, putative | 0.0904 | 0 | 0.5 |
Giardia lamblia | Alanyl dipeptidyl peptidase | 0.0904 | 0 | 0.5 |
Trypanosoma brucei | serine peptidase, Clan SC, Family S9B | 0.5223 | 0.5651 | 1 |
Echinococcus multilocularis | Dipeptidyl peptidase 9 | 0.5223 | 0.5651 | 0.5651 |
Mycobacterium leprae | PROBABLE PROTEASE II PTRBB (OLIGOPEPTIDASE B) | 0.0904 | 0 | 0.5 |
Entamoeba histolytica | hypothetical protein, conserved | 0.0904 | 0 | 0.5 |
Trypanosoma brucei | Dipeptidyl-peptidase 8-like, putative | 0.5223 | 0.5651 | 1 |
Brugia malayi | prolyl oligopeptidase family protein | 0.5223 | 0.5651 | 0.5651 |
Toxoplasma gondii | dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein | 0.3836 | 0.3837 | 1 |
Plasmodium falciparum | peptidase, putative | 0.0904 | 0 | 0.5 |
Plasmodium vivax | hypothetical protein, conserved | 0.0904 | 0 | 0.5 |
Trichomonas vaginalis | Clan SC, family S33, methylesterase-like serine peptidase | 0.0904 | 0 | 0.5 |
Onchocerca volvulus | Dipeptidyl peptidase family member 1 homolog | 0.8546 | 1 | 1 |
Trypanosoma cruzi | serine peptidase, Clan SC, Family S9B | 0.5223 | 0.5651 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.