Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Entamoeba histolytica | protein kinase, putative | 0.0321 | 0.0332 | 1 |
Echinococcus multilocularis | unc 13 (munc13) | 0.024 | 0.0049 | 0.019 |
Echinococcus granulosus | ribosomal protein S6 kinase alpha 3 | 0.0321 | 0.0332 | 0.1291 |
Schistosoma mansoni | serine/threonine kinase | 0.0321 | 0.0332 | 0.1291 |
Echinococcus granulosus | ribosomal protein s6 kinase beta 1 | 0.0321 | 0.0332 | 0.1291 |
Loa Loa (eye worm) | AGC/PKC/IOTA protein kinase | 0.032 | 0.0328 | 0.0328 |
Loa Loa (eye worm) | hypothetical protein | 0.063 | 0.1407 | 0.1407 |
Trichomonas vaginalis | AGC family protein kinase | 0.0321 | 0.0332 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.024 | 0.0049 | 0.0049 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0235 | 0.0031 | 0.012 |
Loa Loa (eye worm) | AGC/RSK/RSK protein kinase | 0.0321 | 0.0332 | 0.0332 |
Toxoplasma gondii | AGC kinase | 0.0321 | 0.0332 | 1 |
Loa Loa (eye worm) | AGC/PKN protein kinase | 0.0321 | 0.0332 | 0.0332 |
Schistosoma mansoni | unc-13 (munc13) | 0.024 | 0.0049 | 0.019 |
Brugia malayi | Protein kinase domain containing protein | 0.0321 | 0.0332 | 0.2235 |
Echinococcus granulosus | NDR protein kinase | 0.0321 | 0.0332 | 0.1291 |
Brugia malayi | Protein kinase domain containing protein | 0.0321 | 0.0332 | 0.2235 |
Echinococcus granulosus | protein kinase c iota type | 0.0627 | 0.1395 | 0.5419 |
Echinococcus granulosus | unc 13 munc13 | 0.024 | 0.0049 | 0.019 |
Brugia malayi | Protein kinase c protein 2 | 0.0653 | 0.1487 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.2779 | 0.8882 | 0.8882 |
Loa Loa (eye worm) | AGC/PKC/ETA protein kinase | 0.0628 | 0.1399 | 0.1399 |
Entamoeba histolytica | protein kinase, putative | 0.0321 | 0.0332 | 1 |
Onchocerca volvulus | 0.024 | 0.0049 | 0.0055 | |
Trichomonas vaginalis | AGC family protein kinase | 0.0321 | 0.0332 | 1 |
Schistosoma mansoni | unc-13 (munc13) | 0.024 | 0.0049 | 0.019 |
Loa Loa (eye worm) | hypothetical protein | 0.0404 | 0.0622 | 0.0622 |
Echinococcus multilocularis | RNA directed DNA polymerase | 0.0404 | 0.0622 | 0.2415 |
Entamoeba histolytica | protein kinase, putative | 0.0321 | 0.0332 | 1 |
Echinococcus multilocularis | ribosomal protein s6 kinase beta 1 | 0.0321 | 0.0332 | 0.1291 |
Trichomonas vaginalis | AGC family protein kinase | 0.0321 | 0.0332 | 1 |
Echinococcus granulosus | Protein kinase C brain isozyme | 0.0966 | 0.2574 | 1 |
Echinococcus granulosus | Serine/threonine-protein kinase Genghis Khan | 0.0235 | 0.0031 | 0.012 |
Loa Loa (eye worm) | AGC/RSK/MSK protein kinase | 0.0321 | 0.0332 | 0.0332 |
Loa Loa (eye worm) | AGC/PKC/ALPHA protein kinase | 0.0427 | 0.0701 | 0.0701 |
Trypanosoma brucei | rac serine-threonine kinase, putative | 0.0321 | 0.0332 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.3005 | 0.9668 | 0.9668 |
Brugia malayi | protein kinase C3,putative | 0.0314 | 0.0308 | 0.2071 |
Echinococcus multilocularis | serine:threonine protein kinase 38 | 0.0321 | 0.0332 | 0.1291 |
Loa Loa (eye worm) | hypothetical protein | 0.2779 | 0.8882 | 0.8882 |
Loa Loa (eye worm) | AGC/RSK/P70 protein kinase | 0.0321 | 0.0332 | 0.0332 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0966 | 0.2574 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0321 | 0.0332 | 1 |
Loa Loa (eye worm) | AGC/DMPK/GEK protein kinase | 0.0321 | 0.0332 | 0.0332 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0628 | 0.1399 | 0.5434 |
Brugia malayi | Phorbol esters/diacylglycerol binding domain | 0.0235 | 0.0031 | 0.0208 |
Schistosoma mansoni | protein kinase C | 0.024 | 0.0049 | 0.019 |
Brugia malayi | Protein kinase domain containing protein | 0.0235 | 0.0031 | 0.0208 |
Trichomonas vaginalis | AGC family protein kinase | 0.0321 | 0.0332 | 1 |
Echinococcus granulosus | serine:threonine protein kinase N2 | 0.0321 | 0.0332 | 0.1291 |
Trichomonas vaginalis | AGC family protein kinase | 0.0321 | 0.0332 | 1 |
Echinococcus multilocularis | serine:threonine protein kinase N2 | 0.0321 | 0.0332 | 0.1291 |
Schistosoma mansoni | atypical protein kinase C | 0.0633 | 0.1415 | 0.5499 |
Echinococcus granulosus | Ribosomal protein S6 kinase beta 2 | 0.0321 | 0.0332 | 0.1291 |
Echinococcus multilocularis | telomerase reverse transcriptase subunit | 0.0404 | 0.0622 | 0.2415 |
Brugia malayi | protein kinase C II. | 0.0628 | 0.1399 | 0.9407 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0321 | 0.0332 | 0.1291 |
Entamoeba histolytica | protein kinase, putative | 0.0321 | 0.0332 | 1 |
Echinococcus multilocularis | C2 calcium dependent membrane targeting | 0.024 | 0.0049 | 0.019 |
Trichomonas vaginalis | AGC family protein kinase | 0.0321 | 0.0332 | 1 |
Loa Loa (eye worm) | CAMK/PKD protein kinase | 0.0235 | 0.0031 | 0.0031 |
Echinococcus granulosus | protein kinase c epsilon type | 0.0628 | 0.1399 | 0.5434 |
Echinococcus granulosus | RNA directed DNA polymerase | 0.0404 | 0.0622 | 0.2415 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0235 | 0.0031 | 0.012 |
Loa Loa (eye worm) | AGC/AKT protein kinase | 0.0321 | 0.0332 | 0.0332 |
Echinococcus multilocularis | Ribosomal protein S6 kinase beta 2 | 0.0321 | 0.0332 | 0.1291 |
Echinococcus multilocularis | Protein kinase C, brain isozyme | 0.0966 | 0.2574 | 1 |
Echinococcus multilocularis | protein kinase c epsilon type | 0.0628 | 0.1399 | 0.5434 |
Echinococcus multilocularis | death associated protein kinase 1 | 0.088 | 0.2276 | 0.8842 |
Onchocerca volvulus | 0.2779 | 0.8882 | 1 | |
Schistosoma mansoni | protein kinase C mu | 0.0235 | 0.0031 | 0.012 |
Brugia malayi | C1-like domain containing protein | 0.0235 | 0.0031 | 0.0208 |
Trichomonas vaginalis | AGC family protein kinase | 0.0321 | 0.0332 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0321 | 0.0332 | 0.1291 |
Brugia malayi | Protein kinase domain containing protein | 0.0321 | 0.0332 | 0.2235 |
Brugia malayi | Hr1 repeat family protein | 0.0321 | 0.0332 | 0.2235 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0321 | 0.0332 | 0.1291 |
Trichomonas vaginalis | AGC family protein kinase | 0.0321 | 0.0332 | 1 |
Trichomonas vaginalis | AGC family protein kinase | 0.0321 | 0.0332 | 1 |
Echinococcus multilocularis | ribosomal protein S6 kinase alpha 3 | 0.0321 | 0.0332 | 0.1291 |
Loa Loa (eye worm) | hypothetical protein | 0.2779 | 0.8882 | 0.8882 |
Echinococcus multilocularis | serine:threonine protein kinase N2 | 0.0388 | 0.0564 | 0.2192 |
Loa Loa (eye worm) | AGC/NDR protein kinase | 0.0321 | 0.0332 | 0.0332 |
Echinococcus multilocularis | serine:threonine protein kinase MRCK beta | 0.0235 | 0.0031 | 0.012 |
Echinococcus multilocularis | serine threonine protein kinase | 0.074 | 0.1789 | 0.6948 |
Echinococcus granulosus | C2 calcium dependent membrane targeting | 0.024 | 0.0049 | 0.019 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0966 | 0.2574 | 1 |
Echinococcus multilocularis | protein kinase c iota type | 0.0627 | 0.1395 | 0.5419 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0321 | 0.0332 | 0.1291 |
Trichomonas vaginalis | AGC family protein kinase | 0.0321 | 0.0332 | 1 |
Brugia malayi | p70 ribosomal S6 kinase beta | 0.0321 | 0.0332 | 0.2235 |
Echinococcus granulosus | protein kinase C gamma type | 0.074 | 0.1789 | 0.6948 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.