Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | solute carrier family 28 | 0.0166 | 0.1912 | 0.1912 |
Schistosoma mansoni | inositol transporter | 0.0832 | 1 | 1 |
Echinococcus multilocularis | concentrative Na+ nucleoside cotransporter | 0.0166 | 0.1912 | 0.1912 |
Brugia malayi | N-terminal motif family protein | 0.0175 | 0.2022 | 0.8175 |
Loa Loa (eye worm) | hypothetical protein | 0.0175 | 0.2022 | 0.8175 |
Onchocerca volvulus | 0.0212 | 0.2474 | 1 | |
Echinococcus granulosus | sodium:myo inositol cotransporter | 0.0832 | 1 | 1 |
Echinococcus granulosus | Na+ dependent nucleoside transporter | 0.0166 | 0.1912 | 0.1912 |
Echinococcus granulosus | high affinity choline transporter 1 | 0.0212 | 0.2474 | 0.2474 |
Onchocerca volvulus | Rap guanine nucleotide exchange factor 1 homolog | 0.0175 | 0.2022 | 0.8175 |
Loa Loa (eye worm) | hypothetical protein | 0.0212 | 0.2474 | 1 |
Schistosoma mansoni | sodium/solute symporter | 0.0212 | 0.2474 | 0.2474 |
Schistosoma mansoni | inositol transporter | 0.0832 | 1 | 1 |
Toxoplasma gondii | transporter, solute:sodium symporter (SSS) family protein | 0.0212 | 0.2474 | 1 |
Echinococcus multilocularis | sodium:myo inositol cotransporter | 0.0832 | 1 | 1 |
Echinococcus granulosus | concentrative Na nucleoside cotransporter | 0.0166 | 0.1912 | 0.1912 |
Brugia malayi | Sodium:solute symporter family protein | 0.0212 | 0.2474 | 1 |
Schistosoma mansoni | high-affinity choline transporter | 0.0212 | 0.2474 | 0.2474 |
Echinococcus multilocularis | sodium:nucleoside cotransporter 2 | 0.0108 | 0.121 | 0.121 |
Echinococcus multilocularis | sodium coupled monocarboxylate transporter 1 | 0.0212 | 0.2474 | 0.2474 |
Brugia malayi | GH02984p | 0.0212 | 0.2474 | 1 |
Echinococcus granulosus | solute carrier family 28 | 0.0166 | 0.1912 | 0.1912 |
Echinococcus multilocularis | high affinity choline transporter 1 | 0.0212 | 0.2474 | 0.2474 |
Loa Loa (eye worm) | hypothetical protein | 0.0212 | 0.2474 | 1 |
Echinococcus granulosus | sodium coupled monocarboxylate transporter 1 | 0.0212 | 0.2474 | 0.2474 |
Echinococcus granulosus | sodium:glucose cotransporter 2 | 0.0832 | 1 | 1 |
Echinococcus granulosus | solute carrier family 5 | 0.0832 | 1 | 1 |
Echinococcus multilocularis | sodium:glucose cotransporter 2 | 0.0832 | 1 | 1 |
Echinococcus multilocularis | solute carrier family 5 | 0.0832 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.