Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0212 | 0.2474 | 1 |
Schistosoma mansoni | high-affinity choline transporter | 0.0212 | 0.2474 | 0.2474 |
Echinococcus granulosus | high affinity choline transporter 1 | 0.0212 | 0.2474 | 0.2474 |
Echinococcus multilocularis | sodium coupled monocarboxylate transporter 1 | 0.0212 | 0.2474 | 0.2474 |
Brugia malayi | Sodium:solute symporter family protein | 0.0212 | 0.2474 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0175 | 0.2022 | 0.8175 |
Schistosoma mansoni | inositol transporter | 0.0832 | 1 | 1 |
Echinococcus multilocularis | sodium:glucose cotransporter 2 | 0.0832 | 1 | 1 |
Onchocerca volvulus | 0.0212 | 0.2474 | 1 | |
Echinococcus granulosus | sodium:glucose cotransporter 2 | 0.0832 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0212 | 0.2474 | 1 |
Schistosoma mansoni | sodium/solute symporter | 0.0212 | 0.2474 | 0.2474 |
Echinococcus granulosus | sodium:myo inositol cotransporter | 0.0832 | 1 | 1 |
Echinococcus granulosus | concentrative Na nucleoside cotransporter | 0.0166 | 0.1912 | 0.1912 |
Echinococcus granulosus | solute carrier family 28 | 0.0166 | 0.1912 | 0.1912 |
Onchocerca volvulus | Rap guanine nucleotide exchange factor 1 homolog | 0.0175 | 0.2022 | 0.8175 |
Schistosoma mansoni | inositol transporter | 0.0832 | 1 | 1 |
Echinococcus multilocularis | solute carrier family 5 | 0.0832 | 1 | 1 |
Brugia malayi | GH02984p | 0.0212 | 0.2474 | 1 |
Echinococcus granulosus | Na+ dependent nucleoside transporter | 0.0166 | 0.1912 | 0.1912 |
Echinococcus granulosus | solute carrier family 5 | 0.0832 | 1 | 1 |
Echinococcus multilocularis | sodium:myo inositol cotransporter | 0.0832 | 1 | 1 |
Echinococcus multilocularis | concentrative Na+ nucleoside cotransporter | 0.0166 | 0.1912 | 0.1912 |
Brugia malayi | N-terminal motif family protein | 0.0175 | 0.2022 | 0.8175 |
Echinococcus granulosus | sodium coupled monocarboxylate transporter 1 | 0.0212 | 0.2474 | 0.2474 |
Echinococcus multilocularis | high affinity choline transporter 1 | 0.0212 | 0.2474 | 0.2474 |
Echinococcus multilocularis | solute carrier family 28 | 0.0166 | 0.1912 | 0.1912 |
Toxoplasma gondii | transporter, solute:sodium symporter (SSS) family protein | 0.0212 | 0.2474 | 1 |
Echinococcus multilocularis | sodium:nucleoside cotransporter 2 | 0.0108 | 0.121 | 0.121 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.