Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | thyroid hormone receptor | 0.0174 | 0.528 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0051 | 0.0966 | 0.218 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0296 | 0.96 | 1 |
Echinococcus granulosus | Mitotic checkpoint protein PRCC C terminal | 0.015 | 0.4432 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0051 | 0.0966 | 0.183 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0296 | 0.96 | 0.96 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0034 | 0.0336 | 0.0637 |
Onchocerca volvulus | 0.0034 | 0.0336 | 0.0393 | |
Loa Loa (eye worm) | hypothetical protein | 0.0034 | 0.0336 | 0.035 |
Trichomonas vaginalis | set domain proteins, putative | 0.0266 | 0.8546 | 0.5 |
Schistosoma mansoni | thyroid hormone receptor | 0.0174 | 0.528 | 1 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0051 | 0.0966 | 0.1007 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0034 | 0.0336 | 0.5 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0051 | 0.0966 | 0.218 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0051 | 0.0966 | 0.183 |
Plasmodium vivax | SET domain protein, putative | 0.0034 | 0.0336 | 0.5 |
Brugia malayi | Pre-SET motif family protein | 0.0034 | 0.0336 | 0.0336 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0051 | 0.0966 | 0.183 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0234 | 0.7406 | 0.7714 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0034 | 0.0336 | 0.0637 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0051 | 0.0966 | 0.183 |
Loa Loa (eye worm) | hypothetical protein | 0.0295 | 0.9552 | 0.995 |
Onchocerca volvulus | 0.0266 | 0.8546 | 1 | |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0296 | 0.96 | 0.96 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0051 | 0.0966 | 0.183 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0034 | 0.0336 | 0.0637 |
Schistosoma mansoni | hypothetical protein | 0.015 | 0.4432 | 0.8394 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0051 | 0.0966 | 0.0966 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0174 | 0.528 | 1 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0034 | 0.0336 | 0.0637 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0034 | 0.0336 | 0.0637 |
Echinococcus multilocularis | Mitotic checkpoint protein PRCC, C terminal | 0.015 | 0.4432 | 0.8394 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0034 | 0.0336 | 0.0637 |
Brugia malayi | Pre-SET motif family protein | 0.0234 | 0.7406 | 0.7406 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0032 | 0.0293 | 0.066 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0034 | 0.0336 | 0.0758 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.