Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Onchocerca volvulus | Prolyl endopeptidase homolog | 0.0148 | 0.1028 | 0.1673 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.0099 | 0.0161 |
Schistosoma mansoni | prolyl oligopeptidase (S09 family) | 0.0148 | 0.1028 | 0.09 |
Entamoeba histolytica | dipeptidyl-peptidase, putative | 0.0148 | 0.1028 | 1 |
Trypanosoma brucei | serine peptidase, Clan SC, Family S9B | 0.1168 | 0.9732 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 0.0141 | 0.023 |
Loa Loa (eye worm) | hypothetical protein | 0.0689 | 0.5643 | 0.9178 |
Entamoeba histolytica | hypothetical protein, conserved | 0.0148 | 0.1028 | 1 |
Echinococcus granulosus | Dipeptidyl peptidase 9 | 0.1168 | 0.9732 | 0.9728 |
Schistosoma mansoni | family C2 unassigned peptidase (C02 family) | 0.0046 | 0.0158 | 0.0017 |
Toxoplasma gondii | hypothetical protein | 0.0148 | 0.1028 | 0.1482 |
Plasmodium falciparum | peptidase, putative | 0.0148 | 0.1028 | 0.5 |
Brugia malayi | Serine protease Z688.6 precursor | 0.0064 | 0.0317 | 0.0183 |
Brugia malayi | Serine carboxypeptidase S28 family protein | 0.0064 | 0.0317 | 0.0183 |
Schistosoma mansoni | prolyl oligopeptidase (S09 family) | 0.0148 | 0.1028 | 0.09 |
Giardia lamblia | Alanyl dipeptidyl peptidase | 0.0148 | 0.1028 | 1 |
Trypanosoma brucei | Dipeptidyl-peptidase 8-like, putative | 0.1168 | 0.9732 | 1 |
Giardia lamblia | Alanyl dipeptidyl peptidase | 0.0148 | 0.1028 | 1 |
Echinococcus multilocularis | prolyl endopeptidase | 0.0148 | 0.1028 | 0.099 |
Echinococcus multilocularis | family C2 unassigned peptidase (C02 family) | 0.0046 | 0.0158 | 0.0116 |
Schistosoma mansoni | family S28 unassigned peptidase (S28 family) | 0.12 | 1 | 1 |
Onchocerca volvulus | Dipeptidyl peptidase family member 1 homolog | 0.0748 | 0.6148 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0148 | 0.1028 | 0.1673 |
Brugia malayi | prolyl oligopeptidase family protein | 0.0148 | 0.1028 | 0.0925 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0148 | 0.1028 | 0.0756 |
Mycobacterium tuberculosis | Probable peptidase | 0.0148 | 0.1028 | 0.5 |
Loa Loa (eye worm) | prolyl oligopeptidase | 0.0748 | 0.6148 | 1 |
Brugia malayi | prolyl oligopeptidase family protein | 0.0148 | 0.1028 | 0.0925 |
Trypanosoma cruzi | serine peptidase, Clan SC, Family S9B | 0.1168 | 0.9732 | 1 |
Trichomonas vaginalis | Clan SC, family S33, methylesterase-like serine peptidase | 0.0148 | 0.1028 | 1 |
Entamoeba histolytica | prolyl oligopeptidase family protein | 0.0148 | 0.1028 | 1 |
Echinococcus multilocularis | Lysosomal Pro X carboxypeptidase | 0.0064 | 0.0317 | 0.0276 |
Loa Loa (eye worm) | calpain family protein 1 | 0.0032 | 0.0042 | 0.0069 |
Echinococcus multilocularis | calpain A | 0.0046 | 0.0158 | 0.0116 |
Trichomonas vaginalis | Clan SC, family S9, acylaminoacyl-peptidase-like serine peptidase | 0.0148 | 0.1028 | 1 |
Toxoplasma gondii | prolyl endopeptidase | 0.0148 | 0.1028 | 0.1482 |
Entamoeba histolytica | prolyl oligopeptidase family protein | 0.0148 | 0.1028 | 1 |
Echinococcus multilocularis | Lysosomal Pro X carboxypeptidase | 0.12 | 1 | 1 |
Mycobacterium leprae | PROBABLE PROTEASE II PTRBB (OLIGOPEPTIDASE B) | 0.0148 | 0.1028 | 0.5 |
Trypanosoma cruzi | dipeptidyl-peptidase 8-like serine peptidase | 0.1168 | 0.9732 | 1 |
Echinococcus granulosus | acylamino acid releasing enzyme | 0.0148 | 0.1028 | 0.0884 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0042 | 0.0069 |
Schistosoma mansoni | family C2 unassigned peptidase (C02 family) | 0.0046 | 0.0158 | 0.0017 |
Onchocerca volvulus | 0.0064 | 0.0317 | 0.0515 | |
Toxoplasma gondii | acylaminoacyl-peptidase, putative | 0.0148 | 0.1028 | 0.1482 |
Loa Loa (eye worm) | calpain family protein 1 | 0.0044 | 0.0141 | 0.023 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0148 | 0.1028 | 0.0756 |
Echinococcus multilocularis | dipeptidyl aminopeptidaseprotein | 0.0748 | 0.6148 | 0.6132 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.0317 | 0.0515 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.0317 | 0.0515 |
Trypanosoma cruzi | oligopeptidase b | 0.0148 | 0.1028 | 0.0756 |
Brugia malayi | prolyl oligopeptidase family protein | 0.0748 | 0.6148 | 0.6263 |
Mycobacterium tuberculosis | Probable protease II PtrBb [second part] (oligopeptidase B) | 0.0148 | 0.1028 | 0.5 |
Mycobacterium ulcerans | protease II (oligopeptidase B), PtrB | 0.0148 | 0.1028 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0148 | 0.1028 | 1 |
Schistosoma mansoni | lysosomal Pro-Xaa carboxypeptidase (S28 family) | 0.0064 | 0.0317 | 0.0178 |
Trypanosoma cruzi | oligopeptidase b | 0.0148 | 0.1028 | 0.0756 |
Plasmodium vivax | hypothetical protein, conserved | 0.0148 | 0.1028 | 0.5 |
Trypanosoma cruzi | oligopeptidase B-like protein, putative | 0.0148 | 0.1028 | 0.0756 |
Entamoeba histolytica | dipeptidyl-peptidase, putative | 0.0148 | 0.1028 | 1 |
Schistosoma mansoni | dipeptidyl-peptidase 9 (S09 family) | 0.1168 | 0.9732 | 0.9728 |
Echinococcus multilocularis | acylamino acid releasing enzyme | 0.0148 | 0.1028 | 0.099 |
Brugia malayi | prolyl oligopeptidase family protein | 0.1168 | 0.9732 | 1 |
Toxoplasma gondii | dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein | 0.0627 | 0.5118 | 1 |
Trypanosoma cruzi | serine peptidase, clan SC, family S9A-like protein, putative | 0.0148 | 0.1028 | 0.0756 |
Brugia malayi | Serine protease Z688.6 precursor | 0.0064 | 0.0317 | 0.0183 |
Echinococcus granulosus | dipeptidyl aminopeptidaseprotein | 0.0748 | 0.6148 | 0.6086 |
Brugia malayi | prolyl oligopeptidase family protein | 0.0148 | 0.1028 | 0.0925 |
Leishmania major | dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B | 0.1168 | 0.9732 | 1 |
Echinococcus granulosus | prolyl endopeptidase | 0.0148 | 0.1028 | 0.0884 |
Trypanosoma cruzi | prolyl endopeptidase | 0.0148 | 0.1028 | 0.0756 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.0317 | 0.0515 |
Loa Loa (eye worm) | hypothetical protein | 0.0479 | 0.3856 | 0.6273 |
Loa Loa (eye worm) | prolyl oligopeptidase | 0.0148 | 0.1028 | 0.1673 |
Schistosoma mansoni | prolyl oligopeptidase (S09 family) | 0.0148 | 0.1028 | 0.09 |
Entamoeba histolytica | prolyl oligopeptidase family protein | 0.0148 | 0.1028 | 1 |
Brugia malayi | hypothetical protein | 0.0479 | 0.3856 | 0.3874 |
Schistosoma mansoni | acylaminoacyl-peptidase (S09 family) | 0.0148 | 0.1028 | 0.09 |
Schistosoma mansoni | subfamily S9B unassigned peptidase (S09 family) | 0.0748 | 0.6148 | 0.6093 |
Loa Loa (eye worm) | hypothetical protein | 0.0148 | 0.1028 | 0.1673 |
Echinococcus granulosus | Lysosomal Pro X carboxypeptidase | 0.0064 | 0.0317 | 0.0161 |
Echinococcus multilocularis | Dipeptidyl peptidase 9 | 0.1168 | 0.9732 | 0.9731 |
Loa Loa (eye worm) | hypothetical protein | 0.0064 | 0.0317 | 0.0515 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.