TDR Targets

Basic information

Technical information

Name: Unnamed compound
MW: 358.498 | Formula: C20H26N2O2S
H donors: 1 H acceptors: 1 LogP: 3.91 Rotable bonds: 8
Rule of 5 violations (Lipinski): 1
SMILES: CCN(CCCNC(=O)c1cc2c(s1)c1c(C)cccc1OC2)CC
InChi: 1S/C20H26N2O2S/c1-4-22(5-2)11-7-10-21-20(23)17-12-15-13-24-16-9-6-8-14(3)18(16)19(15)25-17/h6,8-9,12H,4-5,7,10-11,13H2,1-3H3,(H,21,23)
InChiKey: LJDIINAOSNLLTI-UHFFFAOYSA-N

Network

Hover on a compound node to display the structore

Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

This is a work in progress. Come back soon to try this features!

Clustering layers

This is a work in progress. Come back soon to try this features!

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Schistosoma mansoni	opsin-like receptor	0.0128	0.2448	0.2448
Brugia malayi	Tachykinin-like peptides receptor 99D	0.0128	0.2448	1
Brugia malayi	Putative carbonic anhydrase 5 precursor	0.0053	0.077	0.3143
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0128	0.2448	0.2448
Onchocerca volvulus		0.0128	0.2448	1
Brugia malayi	larval opioid receptor	0.0128	0.2448	1
Schistosoma mansoni	receptor tyrosine phosphatase type r2a	0.0031	0.0266	0.0266
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.0128	0.2448	0.2448
Echinococcus granulosus	g protein coupled receptor	0.0128	0.2448	0.2448
Loa Loa (eye worm)	hypothetical protein	0.0128	0.2448	1
Brugia malayi	Carbonic anhydrase like protein 2 precursor	0.0053	0.077	0.3143
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.0128	0.2448	0.2448
Loa Loa (eye worm)	hypothetical protein	0.0128	0.2448	1
Trichomonas vaginalis	DNA polymerase IV / kappa, putative	0.0019	0	0.5
Echinococcus multilocularis	tachykinin peptides receptor 99D	0.0128	0.2448	0.2448
Loa Loa (eye worm)	hypothetical protein	0.0128	0.2448	1
Mycobacterium ulcerans	DNA polymerase IV	0.0019	0	0.5
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.0128	0.2448	0.2448
Echinococcus multilocularis	dro:myosuppressin receptor	0.0128	0.2448	0.2448
Loa Loa (eye worm)	hypothetical protein	0.0128	0.2448	1
Schistosoma mansoni	neuropeptide F-like receptor	0.0128	0.2448	0.2448
Brugia malayi	Dopamine receptor protein 1, putative (partial)	0.0128	0.2448	1
Onchocerca volvulus	Dopamine\/Ecdysteroid receptor homolog	0.0128	0.2448	1
Brugia malayi	hypothetical protein	0.0128	0.2448	1
Brugia malayi	Unidentified vitellogenin-linked transcript protein 6, putative	0.0128	0.2448	1
Schistosoma mansoni	biogenic amine (octopamine/dopamine) receptor	0.0128	0.2448	0.2448
Schistosoma mansoni	carbonic anhydrase II (carbonate dehydratase II)	0.0053	0.077	0.077
Echinococcus multilocularis	G protein coupled receptor 139	0.0128	0.2448	0.2448
Echinococcus granulosus	carbonic anhydrase	0.0053	0.077	0.077
Mycobacterium tuberculosis	Probable dehydrogenase	0.0085	0.1476	0.8743
Loa Loa (eye worm)	carbonic anhydrase 3	0.0053	0.077	0.3143
Brugia malayi	hypothetical protein	0.0128	0.2448	1
Echinococcus multilocularis	tm gpcr rhodopsin gpcr rhodopsin superfamily	0.0128	0.2448	0.2448
Brugia malayi	putative neuropeptide receptor	0.0128	0.2448	1
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0128	0.2448	0.2448
Echinococcus granulosus	carbonic anhydrase II	0.0053	0.077	0.077
Echinococcus multilocularis	carbonic anhydrase	0.0053	0.077	0.077
Brugia malayi	Dopamine receptor	0.0128	0.2448	1
Brugia malayi	Eukaryotic-type carbonic anhydrase family protein	0.0053	0.077	0.3143
Echinococcus granulosus	dro:myosuppressin receptor	0.0128	0.2448	0.2448
Brugia malayi	ORL1-like opioid receptor	0.0128	0.2448	1
Schistosoma mansoni	biogenic amine receptor	0.0128	0.2448	0.2448
Loa Loa (eye worm)	hypothetical protein	0.0128	0.2448	1
Echinococcus multilocularis	thioredoxin glutathione reductase	0.0038	0.0419	0.0419
Echinococcus multilocularis	neuropeptide receptor A26	0.0128	0.2448	0.2448
Echinococcus granulosus	carbonic anhydrase	0.0053	0.077	0.077
Echinococcus granulosus	alpha 1A adrenergic receptor	0.0128	0.2448	0.2448
Echinococcus granulosus	7TM GPCR rhodopsin	0.0128	0.2448	0.2448
Loa Loa (eye worm)	hypothetical protein	0.0128	0.2448	1
Toxoplasma gondii	hypothetical protein	0.0053	0.077	1
Loa Loa (eye worm)	unidentified vitellogenin-linked transcript protein 6	0.0128	0.2448	1
Leishmania major	trypanothione reductase	0.0037	0.0408	0.5302
Brugia malayi	glutathione reductase	0.0037	0.0408	0.1666
Loa Loa (eye worm)	hypothetical protein	0.0128	0.2448	1
Onchocerca volvulus	Neuropeptide F receptor homolog	0.0128	0.2448	1
Schistosoma mansoni	receptor tyrosine phosphatase type r2a	0.0031	0.0266	0.0266
Brugia malayi	hypothetical protein	0.0128	0.2448	1
Loa Loa (eye worm)	thioredoxin reductase	0.0037	0.0408	0.1666
Echinococcus granulosus	thioredoxin glutathione reductase	0.0038	0.0419	0.0419
Echinococcus granulosus	carbonic anhydrase	0.0053	0.077	0.077
Loa Loa (eye worm)	hypothetical protein	0.0128	0.2448	1
Loa Loa (eye worm)	hypothetical protein	0.0128	0.2448	1
Echinococcus multilocularis	neuropeptides capa receptor	0.0128	0.2448	0.2448
Echinococcus granulosus	biogenic amine 5HT receptor	0.0128	0.2448	0.2448
Onchocerca volvulus		0.0128	0.2448	1
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0128	0.2448	0.2448
Loa Loa (eye worm)	hypothetical protein	0.0128	0.2448	1
Brugia malayi	GnHR receptor homolog	0.0128	0.2448	1
Echinococcus multilocularis	allatostatin A receptor	0.0128	0.2448	0.2448
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0128	0.2448	0.2448
Loa Loa (eye worm)	hypothetical protein	0.0128	0.2448	1
Loa Loa (eye worm)	hypothetical protein	0.0128	0.2448	1
Schistosoma mansoni	myosin xvIII	0.0128	0.2448	0.2448
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0128	0.2448	0.2448
Onchocerca volvulus		0.0128	0.2448	1
Loa Loa (eye worm)	hypothetical protein	0.0128	0.2448	1
Echinococcus granulosus	rhodopsin orphan GPCR	0.0128	0.2448	0.2448
Echinococcus multilocularis	pyroglutamylated rfamide peptide receptor	0.0128	0.2448	0.2448
Loa Loa (eye worm)	hypothetical protein	0.0128	0.2448	1
Loa Loa (eye worm)	hypothetical protein	0.0128	0.2448	1
Echinococcus multilocularis	receptor type tyrosine protein phosphatase protein tyrosine phosphatase receptor type	0.0031	0.0266	0.0266
Loa Loa (eye worm)	hypothetical protein	0.0128	0.2448	1
Schistosoma mansoni	hypothetical protein	0.0128	0.2448	0.2448
Brugia malayi	hypothetical protein	0.0128	0.2448	1
Echinococcus granulosus	rhodopsin orphan GPCR	0.0128	0.2448	0.2448
Onchocerca volvulus		0.0128	0.2448	1
Echinococcus multilocularis	serotonin receptor	0.0128	0.2448	0.2448
Onchocerca volvulus		0.0128	0.2448	1
Echinococcus multilocularis	neuropeptide s receptor	0.0128	0.2448	0.2448
Echinococcus granulosus	tachykinin peptides receptor 99D	0.0128	0.2448	0.2448
Loa Loa (eye worm)	hypothetical protein	0.0053	0.077	0.3143
Echinococcus granulosus	G protein coupled receptor 139	0.0128	0.2448	0.2448
Loa Loa (eye worm)	G-protein-linked acetylcholine receptor protein 2	0.0128	0.2448	1
Loa Loa (eye worm)	hypothetical protein	0.0128	0.2448	1
Trypanosoma cruzi	trypanothione reductase, putative	0.0037	0.0408	0.5302
Echinococcus granulosus	g protein coupled receptor	0.0128	0.2448	0.2448
Mycobacterium leprae	DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE	0.0094	0.1688	1
Loa Loa (eye worm)	eukaryotic-type carbonic anhydrase	0.0053	0.077	0.3143
Echinococcus granulosus	allatostatin A receptor	0.0128	0.2448	0.2448
Schistosoma mansoni	amine GPCR	0.0128	0.2448	0.2448
Onchocerca volvulus		0.0128	0.2448	1
Echinococcus multilocularis	g protein linked acetylcholine receptor gar 2a	0.0128	0.2448	0.2448
Echinococcus granulosus	sex peptide receptor	0.0128	0.2448	0.2448
Loa Loa (eye worm)	neuropeptide F receptor	0.0128	0.2448	1
Loa Loa (eye worm)	gonadotropin-releasing hormone receptor 2	0.0128	0.2448	1
Brugia malayi	hypothetical protein	0.0128	0.2448	1
Schistosoma mansoni	peptide (FMRFamide/somatostatin)-like receptor	0.0128	0.2448	0.2448
Brugia malayi	Melatonin receptor type 1A	0.0128	0.2448	1
Brugia malayi	Eukaryotic-type carbonic anhydrase family protein	0.0053	0.077	0.3143
Schistosoma mansoni	histamine-responsive GPCR (AAF21638)	0.0128	0.2448	0.2448
Schistosoma mansoni	neuropeptide receptor	0.0128	0.2448	0.2448
Echinococcus multilocularis	thyrotropin releasing hormone receptor	0.0128	0.2448	0.2448
Loa Loa (eye worm)	hypothetical protein	0.0128	0.2448	1
Onchocerca volvulus		0.0128	0.2448	1
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0128	0.2448	0.2448
Schistosoma mansoni	carbonic anhydrase	0.0053	0.077	0.077
Echinococcus multilocularis	g protein coupled receptor	0.0128	0.2448	0.2448
Echinococcus granulosus	receptor type tyrosine protein phosphatase	0.0031	0.0266	0.0266
Loa Loa (eye worm)	hypothetical protein	0.0053	0.077	0.3143
Loa Loa (eye worm)	G-protein coupled receptor	0.0128	0.2448	1
Echinococcus multilocularis	G protein coupled 5 hydroxytryptamine receptor	0.0128	0.2448	0.2448
Schistosoma mansoni	neuropeptide receptor	0.0128	0.2448	0.2448
Echinococcus multilocularis	biogenic amine (5HT) receptor	0.0128	0.2448	0.2448
Loa Loa (eye worm)	hypothetical protein	0.0128	0.2448	1
Onchocerca volvulus		0.0128	0.2448	1
Brugia malayi	hypothetical protein	0.0128	0.2448	1
Echinococcus granulosus	somatostatin receptor	0.0128	0.2448	0.2448
Onchocerca volvulus		0.0128	0.2448	1
Loa Loa (eye worm)	hypothetical protein	0.0128	0.2448	1
Loa Loa (eye worm)	TYRA-2 protein	0.0128	0.2448	1
Schistosoma mansoni	carbonic anhydrase II (carbonate dehydratase II)	0.0053	0.077	0.077
Giardia lamblia	DINP protein human, muc B family	0.0019	0	0.5
Echinococcus multilocularis	g protein coupled receptor	0.0128	0.2448	0.2448
Plasmodium vivax	glutathione reductase, putative	0.0037	0.0408	0.5
Loa Loa (eye worm)	follicle stimulating hormone receptor	0.0128	0.2448	1
Schistosoma mansoni	adenoreceptor	0.0128	0.2448	0.2448
Brugia malayi	Eukaryotic-type carbonic anhydrase family protein	0.0053	0.077	0.3143
Echinococcus granulosus	g protein linked acetylcholine receptor gar 2a	0.0128	0.2448	0.2448
Schistosoma mansoni	amine GPCR	0.0128	0.2448	0.2448
Brugia malayi	Eukaryotic-type carbonic anhydrase family protein	0.0053	0.077	0.3143
Echinococcus granulosus	neuropeptide receptor	0.0128	0.2448	0.2448
Loa Loa (eye worm)	melatonin receptor type 1A	0.0128	0.2448	1
Schistosoma mansoni	thyrotropin-releasing hormone receptor	0.0128	0.2448	0.2448
Loa Loa (eye worm)	hypothetical protein	0.0128	0.2448	1
Schistosoma mansoni	receptor protein tyrosine phosphatase	0.0464	1	1
Schistosoma mansoni	neuropeptide f receptor 76f	0.0128	0.2448	0.2448
Echinococcus multilocularis	neuropeptide Y receptor	0.0128	0.2448	0.2448
Echinococcus granulosus	rhodopsin orphan GPCR	0.0128	0.2448	0.2448
Schistosoma mansoni	receptor tyrosine phosphatase type r2a	0.0031	0.0266	0.0266
Mycobacterium tuberculosis	Probable NADH dehydrogenase Ndh	0.0085	0.1476	0.8743
Echinococcus multilocularis	carbonic anhydrase II	0.0053	0.077	0.077
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0128	0.2448	0.2448
Loa Loa (eye worm)	hypothetical protein	0.0128	0.2448	1
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0128	0.2448	0.2448
Entamoeba histolytica	protein tyrosine phosphatase, putative	0.045	0.9691	1
Echinococcus multilocularis	somatostatin receptor	0.0128	0.2448	0.2448
Echinococcus granulosus	biogenic amine 5HT receptor	0.0128	0.2448	0.2448
Schistosoma mansoni	receptor tyrosine phosphatase type r2a	0.0031	0.0266	0.0266
Trichomonas vaginalis	DNA polymerase eta, putative	0.0019	0	0.5
Onchocerca volvulus		0.0128	0.2448	1
Brugia malayi	putative neuropeptide receptor NPR1	0.0128	0.2448	1
Echinococcus granulosus	rhodopsin orphan GPCR	0.0128	0.2448	0.2448
Schistosoma mansoni	opsin-like receptor	0.0128	0.2448	0.2448
Loa Loa (eye worm)	hypothetical protein	0.0128	0.2448	1
Loa Loa (eye worm)	hypothetical protein	0.0128	0.2448	1
Brugia malayi	hypothetical protein	0.0128	0.2448	1
Loa Loa (eye worm)	hypothetical protein	0.0128	0.2448	1
Echinococcus multilocularis	sex peptide receptor	0.0128	0.2448	0.2448
Loa Loa (eye worm)	hypothetical protein	0.0128	0.2448	1
Echinococcus multilocularis	orexin receptor type 2	0.0128	0.2448	0.2448
Echinococcus granulosus	serotonin receptor	0.0128	0.2448	0.2448
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0128	0.2448	0.2448
Loa Loa (eye worm)	hypothetical protein	0.0128	0.2448	1
Brugia malayi	hypothetical protein	0.0128	0.2448	1
Loa Loa (eye worm)	hypothetical protein	0.0128	0.2448	1
Echinococcus granulosus	7tm_1 domain containing protein	0.0128	0.2448	0.2448
Brugia malayi	hypothetical protein	0.0128	0.2448	1
Loa Loa (eye worm)	hypothetical protein	0.0128	0.2448	1
Schistosoma mansoni	peptide (allatostatin/somatostatin)-like receptor	0.0128	0.2448	0.2448
Loa Loa (eye worm)	hypothetical protein	0.0128	0.2448	1
Schistosoma mansoni	amine GPCR	0.0128	0.2448	0.2448
Schistosoma mansoni	muscarinic acetylcholine (GAR) receptor	0.0128	0.2448	0.2448
Brugia malayi	Serotonin/octopamine receptor family protein 7	0.0128	0.2448	1
Loa Loa (eye worm)	hypothetical protein	0.0128	0.2448	1
Echinococcus granulosus	growth hormone secretagogue receptor type 1	0.0128	0.2448	0.2448
Schistosoma mansoni	carbonic anhydrase-related	0.0053	0.077	0.077
Loa Loa (eye worm)	hypothetical protein	0.0128	0.2448	1
Brugia malayi	sulfakinin receptor protein	0.0128	0.2448	1
Echinococcus granulosus	g protein linked acetylcholine receptor gar 2a	0.0128	0.2448	0.2448
Brugia malayi	Serotonin receptor	0.0128	0.2448	1
Echinococcus granulosus	orexin receptor type 2	0.0128	0.2448	0.2448
Loa Loa (eye worm)	neuropeptide F receptor	0.0128	0.2448	1
Schistosoma mansoni	biogenic amine receptor	0.0128	0.2448	0.2448
Echinococcus multilocularis	g protein linked acetylcholine receptor gar 2a	0.0128	0.2448	0.2448
Echinococcus multilocularis	growth hormone secretagogue receptor type 1	0.0128	0.2448	0.2448
Loa Loa (eye worm)	fibronectin type III domain-containing protein	0.0031	0.0266	0.1085
Schistosoma mansoni	neuropeptide receptor	0.0128	0.2448	0.2448
Echinococcus multilocularis	Receptor type tyrosine protein phosphatase O	0.0031	0.0266	0.0266
Echinococcus granulosus	neuropeptide receptor A26	0.0128	0.2448	0.2448
Onchocerca volvulus		0.0128	0.2448	1
Brugia malayi	AKH receptor	0.0128	0.2448	1
Onchocerca volvulus		0.0128	0.2448	1
Mycobacterium tuberculosis	Probable membrane NADH dehydrogenase NdhA	0.0085	0.1476	0.8743
Echinococcus multilocularis	alpha 1A adrenergic receptor	0.0128	0.2448	0.2448
Schistosoma mansoni	biogenic amine receptor	0.0128	0.2448	0.2448
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.0128	0.2448	0.2448
Echinococcus multilocularis	neuropeptide FF receptor 2	0.0128	0.2448	0.2448
Brugia malayi	G-protein coupled receptor	0.0128	0.2448	1
Brugia malayi	RE15519p	0.0128	0.2448	1
Echinococcus granulosus	neuropeptide FF receptor 2	0.0128	0.2448	0.2448
Schistosoma mansoni	growth hormone secretagogue receptor	0.0128	0.2448	0.2448
Echinococcus multilocularis	neuropeptide receptor	0.0128	0.2448	0.2448
Schistosoma mansoni	hypothetical protein	0.0128	0.2448	0.2448
Plasmodium falciparum	carbonic anhydrase	0.0053	0.077	1
Echinococcus multilocularis	neuropeptides capa receptor	0.0128	0.2448	0.2448
Loa Loa (eye worm)	hypothetical protein	0.0128	0.2448	1
Brugia malayi	Protein-tyrosine phosphatase	0.0031	0.0266	0.1085
Loa Loa (eye worm)	5-hydroxytryptamine 2C receptor	0.0128	0.2448	1
Trypanosoma cruzi	carbonic anhydrase-like protein, putative	0.0053	0.077	1
Schistosoma mansoni	alpha-1 adrenergic receptor	0.0128	0.2448	0.2448
Trypanosoma brucei	carbonic anhydrase-like protein	0.0053	0.077	1
Brugia malayi	Carbonic anhydrase like protein 2 precursor	0.0053	0.077	0.3143
Schistosoma mansoni	biogenic amine (5HT) receptor	0.0128	0.2448	0.2448
Echinococcus granulosus	rhodopsin orphan GPCR	0.0128	0.2448	0.2448
Brugia malayi	G-protein-linked acetylcholine receptor protein 2, putative	0.0128	0.2448	1
Echinococcus granulosus	rhodopsin orphan GPCR	0.0128	0.2448	0.2448
Brugia malayi	hypothetical protein	0.0128	0.2448	1
Loa Loa (eye worm)	hypothetical protein	0.0128	0.2448	1
Mycobacterium tuberculosis	Putative ferredoxin reductase	0.0085	0.1476	0.8743
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0128	0.2448	0.2448
Echinococcus granulosus	g-protein coupled receptor	0.0128	0.2448	0.2448
Echinococcus multilocularis	receptor type tyrosine protein phosphatase F	0.0031	0.0266	0.0266
Loa Loa (eye worm)	hypothetical protein	0.0128	0.2448	1
Schistosoma mansoni	neuropeptide receptor	0.0128	0.2448	0.2448
Echinococcus granulosus	neuropeptide Y receptor	0.0128	0.2448	0.2448
Onchocerca volvulus		0.0128	0.2448	1
Loa Loa (eye worm)	hypothetical protein	0.012	0.2277	0.9298
Echinococcus granulosus	thyrotropin releasing hormone receptor	0.0128	0.2448	0.2448
Loa Loa (eye worm)	hypothetical protein	0.0128	0.2448	1
Trypanosoma brucei	trypanothione reductase	0.0037	0.0408	0.5302
Brugia malayi	hypothetical protein	0.012	0.2277	0.9298
Onchocerca volvulus		0.0128	0.2448	1
Loa Loa (eye worm)	hypothetical protein	0.0128	0.2448	1
Mycobacterium tuberculosis	Probable oxidoreductase	0.0094	0.1688	1
Echinococcus granulosus	neuropeptides capa receptor	0.0128	0.2448	0.2448
Echinococcus multilocularis	neuropeptide receptor	0.0128	0.2448	0.2448
Loa Loa (eye worm)	hypothetical protein	0.0128	0.2448	1
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0128	0.2448	0.2448
Loa Loa (eye worm)	hypothetical protein	0.0128	0.2448	1
Brugia malayi	neuropeptide F receptor	0.0128	0.2448	1
Leishmania major	carbonic anhydrase-like protein	0.0053	0.077	1
Brugia malayi	G protein-coupled receptor	0.0128	0.2448	1
Schistosoma mansoni	protein tyrosine phosphatase	0.0031	0.0266	0.0266
Loa Loa (eye worm)	hypothetical protein	0.0128	0.2448	1
Plasmodium vivax	thioredoxin reductase, putative	0.0037	0.0408	0.5
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0128	0.2448	0.2448
Echinococcus granulosus	neuropeptide receptor	0.0128	0.2448	0.2448
Schistosoma mansoni	carbonic anhydrase-related	0.0053	0.077	0.077
Schistosoma mansoni	peptide (FMRFamide/neurokinin-3)-like receptor	0.0128	0.2448	0.2448
Loa Loa (eye worm)	glutathione reductase	0.0037	0.0408	0.1666
Schistosoma mansoni	amine GPCR	0.0128	0.2448	0.2448
Brugia malayi	Dopamine receptor protein 2	0.0128	0.2448	1
Loa Loa (eye worm)	hypothetical protein	0.0128	0.2448	1
Schistosoma mansoni	peptide (allatostatin)-like receptor	0.0128	0.2448	0.2448
Echinococcus granulosus	receptor type tyrosine protein phosphatase	0.0031	0.0266	0.0266
Schistosoma mansoni	amine GPCR	0.0128	0.2448	0.2448
Echinococcus multilocularis	g-protein coupled receptor	0.0128	0.2448	0.2448
Onchocerca volvulus		0.0128	0.2448	1
Schistosoma mansoni	hypothetical protein	0.0128	0.2448	0.2448
Mycobacterium ulcerans	DNA polymerase IV	0.0019	0	0.5
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0128	0.2448	0.2448
Trypanosoma cruzi	carbonic anhydrase-like protein, putative	0.0053	0.077	1
Loa Loa (eye worm)	hypothetical protein	0.0053	0.077	0.3143
Loa Loa (eye worm)	hypothetical protein	0.012	0.2277	0.9298
Echinococcus granulosus	neuropeptide s receptor	0.0128	0.2448	0.2448
Brugia malayi	Serotonin receptor	0.0128	0.2448	1
Schistosoma mansoni	peptide (FMRFamide/somatostatin)-like receptor	0.0128	0.2448	0.2448
Mycobacterium tuberculosis	NADPH-dependent mycothiol reductase Mtr	0.0037	0.0408	0.2417
Brugia malayi	follicle stimulating hormone receptor	0.0128	0.2448	1
Loa Loa (eye worm)	hypothetical protein	0.0128	0.2448	1
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0128	0.2448	0.2448
Loa Loa (eye worm)	G-protein coupled receptor	0.0128	0.2448	1
Mycobacterium tuberculosis	Probable reductase	0.0085	0.1476	0.8743
Schistosoma mansoni	carbonic anhydrase-related	0.0053	0.077	0.077
Schistosoma mansoni	hypothetical protein	0.0128	0.2448	0.2448
Echinococcus granulosus	hypothetical protein	0.0128	0.2448	0.2448
Schistosoma mansoni	hypothetical protein	0.0053	0.077	0.077
Schistosoma mansoni	neuropeptide F-like receptor	0.0128	0.2448	0.2448
Echinococcus granulosus	rhodopsin orphan GPCR	0.0128	0.2448	0.2448
Echinococcus multilocularis	receptor type tyrosine protein phosphatase	0.0031	0.0266	0.0266
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0128	0.2448	0.2448
Echinococcus multilocularis	carbonic anhydrase	0.0053	0.077	0.077
Echinococcus multilocularis	serotonin receptor	0.0128	0.2448	0.2448
Echinococcus multilocularis	rhodopsin orphan GPCR	0.0128	0.2448	0.2448
Echinococcus multilocularis	g protein coupled receptor	0.0128	0.2448	0.2448
Schistosoma mansoni	rhodopsin-like orphan GPCR	0.0128	0.2448	0.2448
Loa Loa (eye worm)	hypothetical protein	0.0128	0.2448	1
Schistosoma mansoni	opsin-like receptor	0.0128	0.2448	0.2448
Echinococcus multilocularis	7TM GPCR, rhodopsin	0.0128	0.2448	0.2448
Echinococcus multilocularis	carbonic anhydrase	0.0053	0.077	0.077
Echinococcus multilocularis	peptide (allatostatin:somatostatin)	0.0128	0.2448	0.2448
Echinococcus granulosus	g protein coupled receptor	0.0128	0.2448	0.2448
Echinococcus multilocularis	receptor type tyrosine protein phosphatase zeta	0.0464	1	1
Schistosoma mansoni	biogenic amine (5HT) receptor	0.0128	0.2448	0.2448
Mycobacterium tuberculosis	Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB	0.0085	0.1476	0.8743
Onchocerca volvulus		0.0128	0.2448	1
Loa Loa (eye worm)	hypothetical protein	0.0128	0.2448	1
Echinococcus granulosus	neuropeptides capa receptor	0.0128	0.2448	0.2448
Echinococcus granulosus	neuropeptide Y receptor	0.0128	0.2448	0.2448
Brugia malayi	G protein-coupled receptor F59B2.13	0.0128	0.2448	1
Brugia malayi	neuropeptide F receptor	0.0128	0.2448	1
Loa Loa (eye worm)	eukaryotic-type carbonic anhydrase	0.0053	0.077	0.3143
Echinococcus granulosus	peptide allatostatin:somatostatin	0.0128	0.2448	0.2448
Brugia malayi	gonadotropin-releasing hormone receptor 2	0.0128	0.2448	1
Echinococcus granulosus	fmrfamide receptor	0.0128	0.2448	0.2448
Brugia malayi	Dopamine receptor protein 1	0.0128	0.2448	1
Loa Loa (eye worm)	hypothetical protein	0.0128	0.2448	1
Mycobacterium tuberculosis	NAD(P)H quinone reductase LpdA	0.0094	0.1688	1
Echinococcus multilocularis	receptor type tyrosine protein phosphatase	0.0031	0.0266	0.0266
Schistosoma mansoni	ancient conserved domain protein 2 (cyclin m2)	0.0128	0.2448	0.2448
Schistosoma mansoni	biogenic amine (dopamine) receptor	0.0128	0.2448	0.2448
Echinococcus granulosus	tm gpcr rhodopsin	0.0128	0.2448	0.2448
Echinococcus multilocularis	neuropeptide Y receptor	0.0128	0.2448	0.2448
Echinococcus granulosus	tm gpcr rhodopsin	0.0128	0.2448	0.2448
Echinococcus granulosus	receptor type tyrosine protein phosphatase	0.0031	0.0266	0.0266
Echinococcus multilocularis	G-protein coupled receptor, putative	0.0128	0.2448	0.2448
Brugia malayi	Thioredoxin reductase	0.0037	0.0408	0.1666
Mycobacterium tuberculosis	Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras	0.0094	0.1688	1
Schistosoma mansoni	histamine h1 receptor	0.0128	0.2448	0.2448
Echinococcus granulosus	tm gpcr rhodopsin	0.0128	0.2448	0.2448
Onchocerca volvulus		0.0128	0.2448	1
Echinococcus multilocularis	fmrfamide receptor	0.0128	0.2448	0.2448
Echinococcus multilocularis	fmrfamide receptor	0.0128	0.2448	0.2448
Echinococcus granulosus	G protein coupled 5 hydroxytryptamine receptor	0.0128	0.2448	0.2448
Echinococcus granulosus	pyroglutamylated rfamide peptide receptor	0.0128	0.2448	0.2448
Brugia malayi	G-protein coupled receptor	0.0128	0.2448	1

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Search by Saint Jude

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.

Detailed information for compound 843674