Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Onchocerca volvulus | Putative sulfate transporter | 0.0204 | 0.0253 | 0.5 |
Mycobacterium tuberculosis | Probable transmembrane carbonic anhydrase (carbonate dehydratase) (carbonic dehydratase) | 0.0383 | 0.1085 | 0.2007 |
Trichomonas vaginalis | conserved hypothetical protein | 0.1117 | 0.4501 | 0.5 |
Brugia malayi | Putative carbonic anhydrase 5 precursor | 0.0149 | 0 | 0.5 |
Trypanosoma cruzi | carbonic anhydrase-like protein, putative | 0.0149 | 0 | 0.5 |
Trypanosoma cruzi | carbonic anhydrase-like protein, putative | 0.0149 | 0 | 0.5 |
Schistosoma mansoni | P2X receptor subunit | 0.2299 | 1 | 1 |
Schistosoma mansoni | carbonic anhydrase | 0.0276 | 0.0591 | 0.0591 |
Schistosoma mansoni | P2X receptor subunit | 0.2299 | 1 | 1 |
Trypanosoma brucei | carbonic anhydrase-like protein | 0.0149 | 0 | 0.5 |
Loa Loa (eye worm) | eukaryotic-type carbonic anhydrase | 0.0149 | 0 | 0.5 |
Loa Loa (eye worm) | carbonic anhydrase 3 | 0.0149 | 0 | 0.5 |
Echinococcus multilocularis | p2X purinoceptor 4 | 0.2299 | 1 | 1 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.0149 | 0 | 0.5 |
Echinococcus granulosus | p2X purinoceptor 4 | 0.2299 | 1 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.1117 | 0.4501 | 0.5 |
Echinococcus granulosus | p2X purinoceptor 4 | 0.2299 | 1 | 1 |
Schistosoma mansoni | P2X receptor subunit | 0.2299 | 1 | 1 |
Schistosoma mansoni | P2X receptor subunit | 0.2299 | 1 | 1 |
Onchocerca volvulus | 0.0204 | 0.0253 | 0.5 | |
Echinococcus multilocularis | p2X purinoceptor 4 | 0.2299 | 1 | 1 |
Mycobacterium leprae | CARBONIC ANHYDRASE (CARBONATE DEHYDRATASE) (CARBONIC DEHYDRATASE) | 0.0276 | 0.0591 | 1 |
Entamoeba histolytica | carbonic anhydrase, putative | 0.0276 | 0.0591 | 0.5 |
Mycobacterium tuberculosis | Beta-carbonic anhydrase | 0.097 | 0.3816 | 1 |
Mycobacterium ulcerans | carbonic anhydrase | 0.1117 | 0.4501 | 1 |
Leishmania major | carbonic anhydrase family protein, putative | 0.0276 | 0.0591 | 1 |
Echinococcus multilocularis | p2X purinoceptor 4 | 0.2299 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.