Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | conserved hypothetical protein | 0.1198 | 1 | 0.5 |
Mycobacterium leprae | CARBONIC ANHYDRASE (CARBONATE DEHYDRATASE) (CARBONIC DEHYDRATASE) | 0.0296 | 0.1314 | 1 |
Trypanosoma brucei | carbonic anhydrase-like protein | 0.016 | 0 | 0.5 |
Echinococcus multilocularis | carbonic anhydrase II | 0.016 | 0 | 0.5 |
Trypanosoma cruzi | carbonic anhydrase-like protein, putative | 0.016 | 0 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.1198 | 1 | 0.5 |
Leishmania major | carbonic anhydrase family protein, putative | 0.0296 | 0.1314 | 1 |
Mycobacterium tuberculosis | Probable transmembrane carbonic anhydrase (carbonate dehydratase) (carbonic dehydratase) | 0.041 | 0.2411 | 0.2007 |
Echinococcus granulosus | carbonic anhydrase II | 0.016 | 0 | 0.5 |
Schistosoma mansoni | carbonic anhydrase | 0.0296 | 0.1314 | 1 |
Onchocerca volvulus | 0.0218 | 0.0562 | 0.5 | |
Onchocerca volvulus | Putative sulfate transporter | 0.0218 | 0.0562 | 0.5 |
Trypanosoma cruzi | carbonic anhydrase-like protein, putative | 0.016 | 0 | 0.5 |
Mycobacterium tuberculosis | Beta-carbonic anhydrase | 0.104 | 0.8477 | 1 |
Loa Loa (eye worm) | carbonic anhydrase 3 | 0.016 | 0 | 0.5 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.016 | 0 | 0.5 |
Entamoeba histolytica | carbonic anhydrase, putative | 0.0296 | 0.1314 | 0.5 |
Loa Loa (eye worm) | eukaryotic-type carbonic anhydrase | 0.016 | 0 | 0.5 |
Brugia malayi | Putative carbonic anhydrase 5 precursor | 0.016 | 0 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.