Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Onchocerca volvulus | Cathepsin L homolog | 0.0157 | 0.1828 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0157 | 0.1828 | 0.1828 |
Brugia malayi | Cathepsin L-like precursor | 0.0157 | 0.1828 | 0.1828 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0157 | 0.1828 | 0.8189 |
Echinococcus multilocularis | cysteine protease | 0.0157 | 0.1828 | 0.1828 |
Giardia lamblia | Cathepsin B precursor | 0.0173 | 0.2232 | 0.5 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0157 | 0.1828 | 1 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.011 | 0.0582 | 0.0582 |
Onchocerca volvulus | 0.0157 | 0.1828 | 1 | |
Brugia malayi | Cathepsin L-like precursor | 0.011 | 0.0582 | 0.0582 |
Brugia malayi | Cathepsin L-like precursor | 0.0157 | 0.1828 | 0.1828 |
Echinococcus granulosus | cathepsin l1 | 0.0157 | 0.1828 | 0.1828 |
Onchocerca volvulus | 0.0157 | 0.1828 | 1 | |
Giardia lamblia | Cathepsin B precursor | 0.0173 | 0.2232 | 0.5 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0157 | 0.1828 | 0.1828 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0157 | 0.1828 | 0.8189 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0157 | 0.1828 | 0.8189 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0157 | 0.1828 | 0.8189 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.011 | 0.0582 | 0.2606 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.047 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0157 | 0.1828 | 0.8189 |
Brugia malayi | Cathepsin L-like precursor | 0.011 | 0.0582 | 0.0582 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0157 | 0.1828 | 0.1323 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0157 | 0.1828 | 0.8189 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0157 | 0.1828 | 0.8189 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0157 | 0.1828 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0157 | 0.1828 | 0.8189 |
Loa Loa (eye worm) | hypothetical protein | 0.047 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0157 | 0.1828 | 0.8189 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0157 | 0.1828 | 0.8189 |
Loa Loa (eye worm) | hypothetical protein | 0.0157 | 0.1828 | 0.1323 |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.047 | 1 | 1 |
Echinococcus granulosus | cathepsin b | 0.047 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0157 | 0.1828 | 0.8189 |
Toxoplasma gondii | cathepsin B | 0.0173 | 0.2232 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0157 | 0.1828 | 0.8189 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0157 | 0.1828 | 0.8189 |
Onchocerca volvulus | 0.0157 | 0.1828 | 1 | |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0157 | 0.1828 | 0.1323 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0157 | 0.1828 | 0.8189 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0157 | 0.1828 | 0.8189 |
Onchocerca volvulus | Cathepsin L homolog | 0.0157 | 0.1828 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0157 | 0.1828 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0157 | 0.1828 | 0.8189 |
Echinococcus multilocularis | cathepsin b | 0.047 | 1 | 1 |
Echinococcus granulosus | cathepsin l1 | 0.011 | 0.0582 | 0.0582 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0173 | 0.2232 | 0.2232 |
Echinococcus multilocularis | cathepsin b | 0.047 | 1 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.047 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0157 | 0.1828 | 0.8189 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.047 | 1 | 1 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.047 | 1 | 1 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0157 | 0.1828 | 0.1828 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0173 | 0.2232 | 1 |
Loa Loa (eye worm) | fibroinase | 0.0157 | 0.1828 | 0.1323 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0157 | 0.1828 | 0.1828 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0157 | 0.1828 | 0.8189 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0157 | 0.1828 | 0.8189 |
Leishmania major | cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like | 0.0173 | 0.2232 | 1 |
Echinococcus multilocularis | cysteine protease | 0.0157 | 0.1828 | 0.1828 |
Giardia lamblia | Cathepsin B precursor | 0.0173 | 0.2232 | 0.5 |
Brugia malayi | cathepsin L-like precursor | 0.011 | 0.0582 | 0.0582 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0157 | 0.1828 | 0.8189 |
Onchocerca volvulus | 0.0157 | 0.1828 | 1 | |
Loa Loa (eye worm) | ctsf protein | 0.0157 | 0.1828 | 0.1323 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.011 | 0.0582 | 0.0582 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0157 | 0.1828 | 0.1828 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0157 | 0.1828 | 0.1828 |
Loa Loa (eye worm) | cysteine protease | 0.0157 | 0.1828 | 0.1323 |
Onchocerca volvulus | 0.0157 | 0.1828 | 1 | |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0157 | 0.1828 | 0.8189 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0157 | 0.1828 | 0.8189 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0157 | 0.1828 | 0.1828 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0157 | 0.1828 | 0.1828 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0157 | 0.1828 | 0.1828 |
Loa Loa (eye worm) | cathepsin B | 0.0173 | 0.2232 | 0.1752 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0157 | 0.1828 | 0.8189 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0157 | 0.1828 | 0.8189 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0157 | 0.1828 | 0.8189 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0157 | 0.1828 | 0.8189 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0157 | 0.1828 | 0.1828 |
Echinococcus granulosus | cathepsin b | 0.047 | 1 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.011 | 0.0582 | 0.3182 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0157 | 0.1828 | 0.8189 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0157 | 0.1828 | 0.1828 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0157 | 0.1828 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0173 | 0.2232 | 0.2232 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0157 | 0.1828 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0157 | 0.1828 | 0.1828 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0157 | 0.1828 | 0.8189 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0157 | 0.1828 | 0.8189 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0157 | 0.1828 | 0.8189 |
Onchocerca volvulus | Cathepsin F homolog | 0.0157 | 0.1828 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0157 | 0.1828 | 0.8189 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0157 | 0.1828 | 0.8189 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0157 | 0.1828 | 0.1828 |
Trypanosoma brucei | cysteine peptidase C (CPC) | 0.0173 | 0.2232 | 1 |
Onchocerca volvulus | 0.0157 | 0.1828 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0157 | 0.1828 | 0.8189 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.011 | 0.0582 | 0.2606 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0157 | 0.1828 | 0.1828 |
Brugia malayi | Cathepsin L-like precursor | 0.0157 | 0.1828 | 0.1828 |
Entamoeba histolytica | cysteine protease, putative | 0.0157 | 0.1828 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0157 | 0.1828 | 0.8189 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0157 | 0.1828 | 0.1828 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0157 | 0.1828 | 0.8189 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.011 | 0.0582 | 0.0582 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0157 | 0.1828 | 0.1828 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0157 | 0.1828 | 0.8189 |
Plasmodium vivax | vivapain-2 | 0.0157 | 0.1828 | 1 |
Onchocerca volvulus | 0.0157 | 0.1828 | 1 | |
Plasmodium vivax | vivapain-2 | 0.0157 | 0.1828 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0157 | 0.1828 | 0.1828 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.