Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.2111 | 0.2059 | 0.2059 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.2111 | 0.2059 | 0.3702 |
Brugia malayi | Cathepsin L-like precursor | 0.2111 | 0.2059 | 0.2059 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.2111 | 0.2059 | 0.2059 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.2111 | 0.2059 | 0.3702 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.4368 | 0.7342 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.2111 | 0.2059 | 0.3702 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.2111 | 0.2059 | 0.3702 |
Onchocerca volvulus | 0.2111 | 0.2059 | 1 | |
Entamoeba histolytica | cysteine proteinase, putative | 0.1512 | 0.0655 | 0.3182 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.2111 | 0.2059 | 1 |
Loa Loa (eye worm) | ctsf protein | 0.2111 | 0.2059 | 0.1502 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.2111 | 0.2059 | 0.3702 |
Onchocerca volvulus | 0.2111 | 0.2059 | 1 | |
Leishmania major | cathepsin L-like protease | 0.4368 | 0.7342 | 1 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.2111 | 0.2059 | 0.1502 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.4368 | 0.7342 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.2111 | 0.2059 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.2111 | 0.2059 | 0.3702 |
Leishmania major | cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like | 0.3607 | 0.5562 | 0.663 |
Echinococcus multilocularis | cathepsin b | 0.5503 | 1 | 1 |
Loa Loa (eye worm) | cysteine protease | 0.2111 | 0.2059 | 0.1502 |
Echinococcus granulosus | cathepsin l1 | 0.1512 | 0.0655 | 0.0655 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.3768 | 0.5938 | 0.5938 |
Plasmodium vivax | vivapain-2 | 0.2111 | 0.2059 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.2111 | 0.2059 | 0.3702 |
Brugia malayi | Cathepsin L-like precursor | 0.2111 | 0.2059 | 0.2059 |
Onchocerca volvulus | 0.2111 | 0.2059 | 1 | |
Brugia malayi | Papain family cysteine protease containing protein | 0.2111 | 0.2059 | 0.2059 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.5503 | 1 | 1 |
Onchocerca volvulus | 0.2111 | 0.2059 | 1 | |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.5503 | 1 | 1 |
Echinococcus multilocularis | cathepsin b | 0.5503 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.4368 | 0.7342 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.4368 | 0.7342 | 0.7342 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.1512 | 0.0655 | 0.0655 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.4368 | 0.7342 | 1 |
Giardia lamblia | Cathepsin B precursor | 0.3607 | 0.5562 | 0.5 |
Onchocerca volvulus | 0.2111 | 0.2059 | 1 | |
Brugia malayi | Cathepsin L-like precursor | 0.1512 | 0.0655 | 0.0655 |
Onchocerca volvulus | 0.2111 | 0.2059 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.2111 | 0.2059 | 0.3702 |
Entamoeba histolytica | cysteine proteinase, putative | 0.2111 | 0.2059 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.4368 | 0.7342 | 1 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.3607 | 0.5562 | 0.5562 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.2111 | 0.2059 | 0.3702 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.4368 | 0.7342 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.2111 | 0.2059 | 0.3702 |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.5503 | 1 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.5503 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.2111 | 0.2059 | 0.3702 |
Echinococcus granulosus | cathepsin b | 0.5503 | 1 | 1 |
Echinococcus granulosus | cathepsin b | 0.5503 | 1 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.5503 | 1 | 1 |
Onchocerca volvulus | Cathepsin L homolog | 0.2111 | 0.2059 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.4368 | 0.7342 | 1 |
Leishmania major | cathepsin L-like protease | 0.4368 | 0.7342 | 1 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.2111 | 0.2059 | 0.2059 |
Brugia malayi | cathepsin L-like precursor | 0.1512 | 0.0655 | 0.0655 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.4368 | 0.7342 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.2111 | 0.2059 | 0.2059 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.4368 | 0.7342 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.2111 | 0.2059 | 0.3702 |
Leishmania major | cathepsin L-like protease | 0.4368 | 0.7342 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.1512 | 0.0655 | 0.0655 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.2111 | 0.2059 | 0.3702 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.2111 | 0.2059 | 0.3702 |
Onchocerca volvulus | 0.2111 | 0.2059 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.2111 | 0.2059 | 0.3702 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.2111 | 0.2059 | 0.2059 |
Onchocerca volvulus | Cathepsin L homolog | 0.2111 | 0.2059 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.1512 | 0.0655 | 0.0655 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.2111 | 0.2059 | 0.3702 |
Brugia malayi | Cathepsin L-like precursor | 0.2111 | 0.2059 | 0.2059 |
Brugia malayi | Cathepsin L-like precursor | 0.2111 | 0.2059 | 0.2059 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.2111 | 0.2059 | 0.2059 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.2111 | 0.2059 | 0.3702 |
Giardia lamblia | Cathepsin B precursor | 0.3607 | 0.5562 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.3607 | 0.5562 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.2111 | 0.2059 | 0.2059 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.4368 | 0.7342 | 0.7342 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.2111 | 0.2059 | 0.3702 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.3607 | 0.5562 | 0.5562 |
Loa Loa (eye worm) | fibroinase | 0.2111 | 0.2059 | 0.1502 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.2111 | 0.2059 | 0.2059 |
Giardia lamblia | Cathepsin B precursor | 0.3607 | 0.5562 | 0.5 |
Entamoeba histolytica | cysteine protease, putative | 0.2111 | 0.2059 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.5503 | 1 | 1 |
Echinococcus granulosus | cathepsin l1 | 0.2111 | 0.2059 | 0.2059 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.2111 | 0.2059 | 0.2059 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.4368 | 0.7342 | 0.7342 |
Toxoplasma gondii | cathepsin B | 0.3607 | 0.5562 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.2111 | 0.2059 | 0.3702 |
Plasmodium vivax | vivapain-2 | 0.2111 | 0.2059 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.4368 | 0.7342 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.2111 | 0.2059 | 0.3702 |
Loa Loa (eye worm) | cathepsin B | 0.3607 | 0.5562 | 0.5251 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.2111 | 0.2059 | 0.1502 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.4368 | 0.7342 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.2111 | 0.2059 | 0.3702 |
Trypanosoma brucei | cysteine peptidase C (CPC) | 0.3607 | 0.5562 | 0.7575 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.4368 | 0.7342 | 0.7342 |
Trypanosoma cruzi | major cysteine proteinase, putative | 0.2889 | 0.3879 | 0.3879 |
Entamoeba histolytica | cysteine proteinase, putative | 0.2111 | 0.2059 | 1 |
Echinococcus multilocularis | cysteine protease | 0.2111 | 0.2059 | 0.2059 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.2111 | 0.2059 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1512 | 0.0655 | 0.1178 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.2111 | 0.2059 | 0.2059 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1512 | 0.0655 | 0.1178 |
Echinococcus multilocularis | cysteine protease | 0.2111 | 0.2059 | 0.2059 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.2111 | 0.2059 | 0.3702 |
Onchocerca volvulus | Cathepsin F homolog | 0.2111 | 0.2059 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.2111 | 0.2059 | 0.1502 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.2111 | 0.2059 | 0.3702 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.2111 | 0.2059 | 0.3702 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.2111 | 0.2059 | 0.2059 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.2111 | 0.2059 | 0.3702 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.