Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Giardia lamblia | Kinase, CMGC CDK | 0.0045 | 0.0734 | 0.5 |
Echinococcus multilocularis | cyclin dependent kinase 5 | 0.0045 | 0.0734 | 0.5 |
Loa Loa (eye worm) | CMGC/CDK/CDC2 protein kinase | 0.0045 | 0.0734 | 1 |
Echinococcus granulosus | cyclin dependent kinase 5 | 0.0045 | 0.0734 | 0.5 |
Plasmodium falciparum | protein kinase 5 | 0.0045 | 0.0734 | 0.5 |
Echinococcus multilocularis | cyclin dependent kinase 1 | 0.0045 | 0.0734 | 0.5 |
Entamoeba histolytica | cell division protein kinase 2, putative | 0.0045 | 0.0734 | 0.5 |
Echinococcus granulosus | 5'partial|cyclin dependent kinase 1 | 0.0045 | 0.0734 | 0.5 |
Brugia malayi | cell division control protein 2 homolog | 0.0045 | 0.0734 | 0.5 |
Trypanosoma brucei | wee1-like protein kinase | 0.0057 | 1 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0045 | 0.0734 | 0.5 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0045 | 0.0734 | 0.5 |
Trypanosoma cruzi | Wee1-like protein kinase, putative | 0.0057 | 1 | 1 |
Echinococcus multilocularis | cyclin dependent kinase 1 | 0.0045 | 0.0734 | 0.5 |
Loa Loa (eye worm) | CMGC/CDK/CDK5 protein kinase | 0.0045 | 0.0734 | 1 |
Trypanosoma cruzi | Wee1-like protein kinase, putative | 0.0057 | 1 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0045 | 0.0734 | 0.5 |
Leishmania major | serine/threonine-protein kinase, putative,protein kinase, putative | 0.0057 | 1 | 1 |
Brugia malayi | Protein kinase domain containing protein | 0.0045 | 0.0734 | 0.5 |
Echinococcus granulosus | cyclin dependent kinase | 0.0045 | 0.0734 | 0.5 |
Toxoplasma gondii | cell-cycle-associated protein kinase CDK, putative | 0.0045 | 0.0734 | 0.5 |
Trypanosoma cruzi | Wee1-like protein kinase, putative | 0.0057 | 1 | 1 |
Giardia lamblia | Kinase, CMGC CDK | 0.0045 | 0.0734 | 0.5 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0045 | 0.0734 | 0.5 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0045 | 0.0734 | 0.5 |
Echinococcus granulosus | cyclin dependent kinase 1 | 0.0045 | 0.0734 | 0.5 |
Plasmodium vivax | protein kinase Crk2 | 0.0045 | 0.0734 | 0.5 |
Echinococcus multilocularis | cyclin dependent kinase | 0.0045 | 0.0734 | 0.5 |
Loa Loa (eye worm) | CMGC/CDK/CDC2 protein kinase | 0.0045 | 0.0734 | 1 |
Entamoeba histolytica | cell division protein kinase 2, putative | 0.0045 | 0.0734 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.