Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0197 | 0.0814 | 1 |
Trypanosoma cruzi | Peptide deformylase 2, putative | 0.0734 | 0.3672 | 1 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0044 | 0 | 0.5 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0197 | 0.0814 | 0.1939 |
Onchocerca volvulus | 0.0114 | 0.0373 | 0.5 | |
Echinococcus granulosus | microtubule associated protein 2 | 0.0833 | 0.4201 | 1 |
Brugia malayi | MH2 domain containing protein | 0.0144 | 0.0535 | 0.6566 |
Leishmania major | polypeptide deformylase-like protein, putative | 0.0734 | 0.3672 | 1 |
Toxoplasma gondii | hypothetical protein | 0.1923 | 1 | 1 |
Trypanosoma cruzi | polypeptide deformylase-like protein, putative | 0.0734 | 0.3672 | 1 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0044 | 0 | 0.5 |
Trichomonas vaginalis | maltase-glucoamylase, putative | 0.0044 | 0 | 0.5 |
Mycobacterium leprae | PROBABLE POLYPEPTIDE DEFORMYLASE DEF (PDF) (FORMYLMETHIONINE DEFORMYLASE) | 0.1923 | 1 | 0.5 |
Trichomonas vaginalis | sucrase-isomaltase, putative | 0.0044 | 0 | 0.5 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0044 | 0 | 0.5 |
Trypanosoma cruzi | polypeptide deformylase-like protein, putative | 0.0734 | 0.3672 | 1 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0044 | 0 | 0.5 |
Wolbachia endosymbiont of Brugia malayi | peptide deformylase | 0.1923 | 1 | 0.5 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0044 | 0 | 0.5 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0044 | 0 | 0.5 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0197 | 0.0814 | 1 |
Echinococcus granulosus | lysosomal alpha glucosidase | 0.0197 | 0.0814 | 0.1939 |
Plasmodium falciparum | peptide deformylase | 0.1923 | 1 | 0.5 |
Treponema pallidum | polypeptide deformylase (def) | 0.1923 | 1 | 0.5 |
Schistosoma mansoni | alpha-glucosidase | 0.0169 | 0.0669 | 0.1592 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0197 | 0.0814 | 0.1939 |
Mycobacterium tuberculosis | Probable polypeptide deformylase Def (PDF) (formylmethionine deformylase) | 0.1923 | 1 | 0.5 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0044 | 0 | 0.5 |
Plasmodium vivax | peptide deformylase, putative | 0.1923 | 1 | 0.5 |
Trypanosoma brucei | Polypeptide deformylase 1 | 0.0734 | 0.3672 | 1 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0833 | 0.4201 | 1 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0144 | 0.0535 | 0.6566 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0044 | 0 | 0.5 |
Schistosoma mansoni | alpha-glucosidase | 0.0169 | 0.0669 | 0.1592 |
Trypanosoma cruzi | Peptide deformylase 2, putative | 0.0734 | 0.3672 | 1 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0144 | 0.0535 | 0.6566 |
Schistosoma mansoni | microtubule-associated protein tau | 0.0833 | 0.4201 | 1 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0044 | 0 | 0.5 |
Mycobacterium ulcerans | peptide deformylase | 0.1923 | 1 | 0.5 |
Trypanosoma brucei | Peptide deformylase 2 | 0.0734 | 0.3672 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.