Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | serine/threonine protein kinase 6 | 0.0128 | 0.2248 | 0.2248 |
Schistosoma mansoni | tyrosine kinase | 0.0109 | 0.1845 | 0.1628 |
Echinococcus multilocularis | ryanodine receptor 44f | 0.0315 | 0.6154 | 0.7602 |
Brugia malayi | serine/threonine kinase 12 | 0.0128 | 0.2248 | 0.2248 |
Entamoeba histolytica | serine/threonine- protein kinase 6 , putative | 0.0128 | 0.2248 | 1 |
Schistosoma mansoni | tyrosine kinase | 0.0179 | 0.3307 | 0.3128 |
Entamoeba histolytica | protein kinase domain containing protein | 0.0128 | 0.2248 | 1 |
Echinococcus granulosus | epidermal growth factor receptor | 0.0183 | 0.338 | 0.4024 |
Loa Loa (eye worm) | AUR protein kinase | 0.0128 | 0.2248 | 0.3385 |
Schistosoma mansoni | tyrosine kinase | 0.0338 | 0.664 | 0.6551 |
Loa Loa (eye worm) | TK/INSR protein kinase | 0.0109 | 0.1845 | 0.2779 |
Schistosoma mansoni | inositol 145-trisphosphate receptor | 0.0153 | 0.2752 | 0.2559 |
Echinococcus granulosus | aurora kinase A | 0.0128 | 0.2248 | 0.2564 |
Loa Loa (eye worm) | hypothetical protein | 0.0095 | 0.1547 | 0.233 |
Plasmodium vivax | serine/threonine protein kinase 6, putative | 0.0128 | 0.2248 | 0.5 |
Echinococcus granulosus | insulin growth factor 1 receptor beta | 0.0109 | 0.1845 | 0.2045 |
Onchocerca volvulus | 0.0033 | 0.026 | 0.5 | |
Toxoplasma gondii | aurora kinase | 0.0128 | 0.2248 | 0.5 |
Leishmania major | protein kinase, putative | 0.0128 | 0.2248 | 1 |
Entamoeba histolytica | protein kinase , putative | 0.0128 | 0.2248 | 1 |
Schistosoma mansoni | tyrosine kinase | 0.0179 | 0.3307 | 0.3128 |
Loa Loa (eye worm) | hypothetical protein | 0.0315 | 0.6154 | 0.9267 |
Plasmodium falciparum | serine/threonine protein kinase, putative | 0.0128 | 0.2248 | 0.5 |
Echinococcus multilocularis | 0.0104 | 0.1742 | 0.1911 | |
Loa Loa (eye worm) | TK/EGFR protein kinase | 0.0338 | 0.664 | 1 |
Echinococcus granulosus | epidermal growth factor receptor | 0.0338 | 0.664 | 0.8229 |
Schistosoma mansoni | protein kinase | 0.0128 | 0.2248 | 0.2041 |
Entamoeba histolytica | protein kinase, putative | 0.0128 | 0.2248 | 1 |
Brugia malayi | Furin-like cysteine rich region family protein | 0.0338 | 0.664 | 0.664 |
Entamoeba histolytica | serine/threonine protein kinase 6, putative | 0.0128 | 0.2248 | 1 |
Echinococcus granulosus | ryanodine receptor 44f | 0.0404 | 0.8013 | 1 |
Echinococcus multilocularis | serine:threonine protein kinase 12 B | 0.0128 | 0.2248 | 0.2564 |
Schistosoma mansoni | tyrosine kinase | 0.0183 | 0.338 | 0.3203 |
Schistosoma mansoni | tyrosine kinase | 0.0179 | 0.3307 | 0.3128 |
Echinococcus multilocularis | insulin growth factor 1 receptor beta | 0.0109 | 0.1845 | 0.2045 |
Trypanosoma cruzi | inositol 1,4,5-trisphosphate receptor, putative | 0.018 | 0.3324 | 1 |
Loa Loa (eye worm) | ryanodine receptor | 0.0118 | 0.2024 | 0.3048 |
Echinococcus multilocularis | epidermal growth factor receptor | 0.0338 | 0.664 | 0.8229 |
Echinococcus granulosus | ryanodine receptor 44f | 0.0315 | 0.6154 | 0.7602 |
Entamoeba histolytica | protein kinase, putative | 0.0128 | 0.2248 | 1 |
Loa Loa (eye worm) | AUR protein kinase | 0.0128 | 0.2248 | 0.3385 |
Echinococcus granulosus | insulin receptor | 0.0109 | 0.1845 | 0.2045 |
Brugia malayi | serine/threonine-protein kinase 6 | 0.0128 | 0.2248 | 0.2248 |
Brugia malayi | MIR domain containing protein | 0.0033 | 0.026 | 0.026 |
Loa Loa (eye worm) | MIR domain-containing protein | 0.0033 | 0.026 | 0.0391 |
Echinococcus multilocularis | insulin receptor | 0.0109 | 0.1845 | 0.2045 |
Schistosoma mansoni | inositol 145-trisphosphate receptor | 0.0061 | 0.0832 | 0.0588 |
Giardia lamblia | Aurora kinase | 0.0128 | 0.2248 | 0.5 |
Trichomonas vaginalis | AGC family protein kinase | 0.0128 | 0.2248 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0061 | 0.0832 | 0.1253 |
Trypanosoma brucei | inositol 1,4,5-trisphosphate receptor | 0.018 | 0.3324 | 1 |
Echinococcus granulosus | serine:threonine protein kinase 12 B | 0.0128 | 0.2248 | 0.2564 |
Schistosoma mansoni | tyrosine kinase | 0.0109 | 0.1845 | 0.1628 |
Schistosoma mansoni | ryanodine receptor 1 skeletal muscle | 0.0058 | 0.0766 | 0.0519 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0128 | 0.2248 | 0.2041 |
Brugia malayi | cation channel family protein | 0.0213 | 0.4024 | 0.4024 |
Brugia malayi | Protein kinase domain containing protein | 0.0109 | 0.1845 | 0.1845 |
Schistosoma mansoni | hypothetical protein | 0.0123 | 0.2135 | 0.1925 |
Trichomonas vaginalis | AGC family protein kinase | 0.0128 | 0.2248 | 1 |
Loa Loa (eye worm) | ryanodine receptor | 0.0186 | 0.346 | 0.5211 |
Loa Loa (eye worm) | AUR protein kinase | 0.0128 | 0.2248 | 0.3385 |
Schistosoma mansoni | tyrosine kinase | 0.0183 | 0.338 | 0.3203 |
Trichomonas vaginalis | AGC family protein kinase | 0.0128 | 0.2248 | 1 |
Echinococcus multilocularis | ryanodine receptor 44f | 0.0404 | 0.8013 | 1 |
Echinococcus granulosus | melanoma receptor tyrosine protein kinase | 0.0183 | 0.338 | 0.4024 |
Echinococcus multilocularis | aurora kinase A | 0.0128 | 0.2248 | 0.2564 |
Loa Loa (eye worm) | hypothetical protein | 0.0091 | 0.1465 | 0.2206 |
Trichomonas vaginalis | AGC family protein kinase | 0.0128 | 0.2248 | 1 |
Schistosoma mansoni | ryanodine receptor related | 0.0499 | 1 | 1 |
Echinococcus multilocularis | epidermal growth factor receptor | 0.0183 | 0.338 | 0.4024 |
Entamoeba histolytica | serine/threonine- protein kinase 6, putative | 0.0128 | 0.2248 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.