Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0194 | 0.1297 | 1 |
Leishmania major | histone deacetylase, putative | 0.0194 | 0.1297 | 1 |
Plasmodium vivax | histone deacetylase 2, putative | 0.0194 | 0.1297 | 0.5 |
Leishmania major | histone deacetylase, putative | 0.0194 | 0.1297 | 1 |
Mycobacterium ulcerans | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | 0.1316 | 1 | 1 |
Echinococcus granulosus | geminin | 0.0174 | 0.114 | 0.8789 |
Wolbachia endosymbiont of Brugia malayi | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | 0.1316 | 1 | 0.5 |
Echinococcus multilocularis | histone deacetylase 6 | 0.0194 | 0.1297 | 1 |
Mycobacterium tuberculosis | Probable UDP-N-acetylglucosamine 1-carboxyvinyltransferase MurA | 0.0945 | 0.7123 | 0.5 |
Trypanosoma brucei | histone deacetylase, putative | 0.0194 | 0.1297 | 1 |
Toxoplasma gondii | shikimate dehydrogenase substrate binding domain-containing protein | 0.0371 | 0.2671 | 1 |
Onchocerca volvulus | 0.0155 | 0.0995 | 1 | |
Plasmodium vivax | histone deacetylase, putative | 0.0194 | 0.1297 | 0.5 |
Treponema pallidum | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | 0.1316 | 1 | 0.5 |
Trypanosoma cruzi | histone deacetylase, putative | 0.0194 | 0.1297 | 1 |
Loa Loa (eye worm) | histone deacetylase 7A | 0.0194 | 0.1297 | 1 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0029 | 0.0021 | 0.0164 |
Schistosoma mansoni | histone deacetylase hda2 | 0.0194 | 0.1297 | 1 |
Echinococcus multilocularis | histone deacetylase 6 | 0.0194 | 0.1297 | 1 |
Schistosoma mansoni | tyrosyl-DNA phosphodiesterase | 0.0065 | 0.0299 | 0.2304 |
Brugia malayi | hypothetical protein | 0.0155 | 0.0995 | 0.7666 |
Brugia malayi | Tyrosyl-DNA phosphodiesterase family protein | 0.0065 | 0.0299 | 0.2304 |
Echinococcus multilocularis | histone deacetylase 7 | 0.0194 | 0.1297 | 1 |
Trichomonas vaginalis | MYB, putative | 0.0029 | 0.0018 | 1 |
Echinococcus multilocularis | transcription factor Dp 1 | 0.0038 | 0.0086 | 0.0666 |
Schistosoma mansoni | histone deacetylase 4 5 | 0.0194 | 0.1297 | 1 |
Echinococcus granulosus | histone deacetylase | 0.0194 | 0.1297 | 1 |
Trypanosoma brucei | histone deacetylase 3 | 0.0194 | 0.1297 | 1 |
Echinococcus granulosus | histone deacetylase 7 | 0.0194 | 0.1297 | 1 |
Echinococcus granulosus | transcription factor Dp 1 | 0.0038 | 0.0086 | 0.0666 |
Schistosoma mansoni | histone deacetylase 4 5 | 0.0194 | 0.1297 | 1 |
Plasmodium falciparum | histone deacetylase 2 | 0.0194 | 0.1297 | 0.5 |
Brugia malayi | Histone deacetylase family protein | 0.0194 | 0.1297 | 1 |
Entamoeba histolytica | tyrosyl-DNA phosphodiesterase, putative | 0.0065 | 0.0299 | 1 |
Plasmodium falciparum | histone deacetylase, putative | 0.0194 | 0.1297 | 0.5 |
Echinococcus multilocularis | histone deacetylase | 0.0194 | 0.1297 | 1 |
Mycobacterium leprae | PROBABLE UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYLTRANSFERASE MURA | 0.0945 | 0.7123 | 1 |
Toxoplasma gondii | histone deacetylase HDAC1 | 0.0194 | 0.1297 | 0.4821 |
Echinococcus multilocularis | geminin | 0.0174 | 0.114 | 0.8789 |
Loa Loa (eye worm) | hypothetical protein | 0.0155 | 0.0995 | 0.7666 |
Loa Loa (eye worm) | hypothetical protein | 0.0194 | 0.1297 | 1 |
Echinococcus multilocularis | tyrosyl DNA phosphodiesterase 1 | 0.0065 | 0.0299 | 0.2304 |
Trypanosoma brucei | histone deacetylase 4 | 0.0194 | 0.1297 | 1 |
Trypanosoma cruzi | histone deacetylase, putative | 0.0194 | 0.1297 | 1 |
Echinococcus granulosus | histone deacetylase 6 | 0.0194 | 0.1297 | 1 |
Echinococcus granulosus | histone deacetylase 6 | 0.0194 | 0.1297 | 1 |
Loa Loa (eye worm) | tyrosyl-DNA phosphodiesterase | 0.0065 | 0.0299 | 0.2304 |
Brugia malayi | Cytochrome P450 family protein | 0.0029 | 0.0021 | 0.0164 |
Echinococcus granulosus | histone deacetylase 6 | 0.0194 | 0.1297 | 1 |
Giardia lamblia | Myb 1-like protein | 0.0029 | 0.0018 | 0.5 |
Loa Loa (eye worm) | histone deacetylase | 0.0194 | 0.1297 | 1 |
Echinococcus granulosus | tyrosyl DNA phosphodiesterase 1 | 0.0065 | 0.0299 | 0.2304 |
Trichomonas vaginalis | r2r3-MYB transcription factor, putative | 0.0029 | 0.0018 | 1 |
Echinococcus multilocularis | histone deacetylase 6 | 0.0194 | 0.1297 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0174 | 0.114 | 0.8789 |
Brugia malayi | Histone deacetylase family protein | 0.0194 | 0.1297 | 1 |
Trichomonas vaginalis | r2r3-MYB transcription factor, putative | 0.0029 | 0.0018 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0174 | 0.114 | 0.8789 |
Trypanosoma cruzi | histone deacetylase, putative | 0.0194 | 0.1297 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.