Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | poly ADP ribose polymerase 1 | 0.0302 | 0.9569 | 1 |
Echinococcus granulosus | poly (ADP ribose) polymerase | 0.0094 | 0.1982 | 0.1839 |
Trypanosoma brucei | poly(adp-ribose) polymerase | 0.0166 | 0.461 | 1 |
Echinococcus granulosus | poly adp ribose polymerase 2 | 0.0166 | 0.461 | 0.4666 |
Loa Loa (eye worm) | hypothetical protein | 0.0166 | 0.461 | 0.6641 |
Leishmania major | DNA repair protein, putative | 0.0039 | 0 | 0.5 |
Trypanosoma cruzi | poly(ADP-ribose) polymerase, putative | 0.0166 | 0.461 | 1 |
Echinococcus granulosus | WGR domain containing protein | 0.0094 | 0.1982 | 0.1839 |
Schistosoma mansoni | poly [ADP-ribose] polymerase | 0.0166 | 0.461 | 0.1413 |
Leishmania major | hypothetical protein, conserved | 0.0039 | 0 | 0.5 |
Loa Loa (eye worm) | poly(ADP-ribose) polymerase | 0.0119 | 0.29 | 0.4179 |
Brugia malayi | WGR domain containing protein | 0.0302 | 0.9569 | 1 |
Schistosoma mansoni | poly [ADP-ribose] polymerase | 0.0302 | 0.9569 | 1 |
Echinococcus multilocularis | poly (ADP ribose) polymerase 1 | 0.0302 | 0.9569 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.023 | 0.6941 | 1 |
Entamoeba histolytica | poly(ADP-ribose) polymerase, putative | 0.0302 | 0.9569 | 1 |
Echinococcus multilocularis | poly (adp ribose) polymerase 2 | 0.0166 | 0.461 | 0.4152 |
Onchocerca volvulus | DNA ligase 3 homolog | 0.0039 | 0 | 0.5 |
Trypanosoma cruzi | poly(ADP-ribose) polymerase, putative | 0.0166 | 0.461 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.