Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | endoplasmin | 0.044 | 0.5251 | 0.655 |
Leishmania major | heat shock protein 83-1 | 0.0552 | 0.8017 | 1 |
Onchocerca volvulus | Heat shock protein 75 kDa, mitochondrial homolog | 0.0226 | 0 | 0.5 |
Brugia malayi | Endoplasmin precursor | 0.0552 | 0.8017 | 1 |
Leishmania major | heat shock protein 83-1 | 0.0552 | 0.8017 | 1 |
Trypanosoma cruzi | heat shock protein 90, putative | 0.044 | 0.5251 | 0.655 |
Toxoplasma gondii | heat shock protein 90, putative | 0.0552 | 0.8017 | 1 |
Echinococcus granulosus | heat shock protein 90 | 0.0552 | 0.8017 | 1 |
Brugia malayi | heat shock protein 90 | 0.0552 | 0.8017 | 1 |
Leishmania major | heat shock protein 83-1 | 0.0552 | 0.8017 | 1 |
Echinococcus granulosus | heat shock protein 90 | 0.044 | 0.5251 | 0.655 |
Leishmania major | heat shock protein 83-1 | 0.0552 | 0.8017 | 1 |
Mycobacterium leprae | PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) | 0.044 | 0.5251 | 0.5 |
Trichomonas vaginalis | heat shock protein, putative | 0.044 | 0.5251 | 0.655 |
Trichomonas vaginalis | heat shock protein, putative | 0.044 | 0.5251 | 0.655 |
Toxoplasma gondii | heat shock protein HSP90 | 0.0552 | 0.8017 | 1 |
Wolbachia endosymbiont of Brugia malayi | heat shock protein 90 | 0.044 | 0.5251 | 0.5 |
Schistosoma mansoni | endoplasmin | 0.0552 | 0.8017 | 1 |
Trypanosoma brucei | heat shock protein 90, putative | 0.0552 | 0.8017 | 1 |
Trichomonas vaginalis | heat shock protein, putative | 0.0552 | 0.8017 | 1 |
Trypanosoma brucei | heat shock protein, putative | 0.0552 | 0.8017 | 1 |
Giardia lamblia | Heat shock protein HSP 90-alpha | 0.0552 | 0.8017 | 1 |
Leishmania major | heat shock protein 83-1 | 0.0552 | 0.8017 | 1 |
Echinococcus granulosus | heat shock protein heat shock protein 90 alpha | 0.044 | 0.5251 | 0.655 |
Leishmania major | heat shock protein 83-1 | 0.0552 | 0.8017 | 1 |
Mycobacterium ulcerans | arylamine N-acetyltransferase Nat | 0.0633 | 1 | 1 |
Leishmania major | heat shock protein 83-1 | 0.0552 | 0.8017 | 1 |
Trichomonas vaginalis | heat shock protein, putative | 0.044 | 0.5251 | 0.655 |
Loa Loa (eye worm) | endoplasmin | 0.0552 | 0.8017 | 1 |
Leishmania major | heat shock protein 83-1 | 0.0552 | 0.8017 | 1 |
Entamoeba histolytica | heat shock protein 90, putative | 0.0552 | 0.8017 | 1 |
Leishmania major | heat shock protein 83-1 | 0.0552 | 0.8017 | 1 |
Treponema pallidum | heat shock protein 90 | 0.044 | 0.5251 | 0.5 |
Plasmodium vivax | endoplasmin, putative | 0.0552 | 0.8017 | 1 |
Leishmania major | lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative | 0.044 | 0.5251 | 0.655 |
Echinococcus multilocularis | heat shock protein 90 | 0.0552 | 0.8017 | 1 |
Plasmodium vivax | heat shock protein 86, putative | 0.0552 | 0.8017 | 1 |
Trypanosoma brucei | heat shock protein, putative | 0.0552 | 0.8017 | 1 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.0552 | 0.8017 | 1 |
Leishmania major | heat shock protein 83-1 | 0.0552 | 0.8017 | 1 |
Loa Loa (eye worm) | heat shock protein 90 | 0.0552 | 0.8017 | 1 |
Trypanosoma cruzi | heat shock protein 90, putative | 0.0326 | 0.2452 | 0.3058 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.0552 | 0.8017 | 1 |
Leishmania major | heat shock protein 83-1 | 0.0552 | 0.8017 | 1 |
Trichomonas vaginalis | heat shock protein, putative | 0.0339 | 0.2766 | 0.345 |
Leishmania major | heat shock protein 83-1 | 0.0552 | 0.8017 | 1 |
Trypanosoma cruzi | heat shock protein 90, putative | 0.0552 | 0.8017 | 1 |
Schistosoma mansoni | endoplasmin | 0.0552 | 0.8017 | 1 |
Echinococcus granulosus | heat shock protein | 0.0552 | 0.8017 | 1 |
Trypanosoma brucei | heat shock protein, putative | 0.0552 | 0.8017 | 1 |
Trypanosoma cruzi | Heat shock protein 83, putative | 0.0552 | 0.8017 | 1 |
Trypanosoma brucei | heat shock protein, putative | 0.0552 | 0.8017 | 1 |
Trypanosoma brucei | heat shock protein, putative | 0.0552 | 0.8017 | 1 |
Schistosoma mansoni | heat shock protein | 0.0552 | 0.8017 | 1 |
Trypanosoma brucei | heat shock protein, putative | 0.0552 | 0.8017 | 1 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.0552 | 0.8017 | 1 |
Trichomonas vaginalis | endoplasmin, putative | 0.0339 | 0.2766 | 0.345 |
Trypanosoma brucei | heat shock protein 90, putative | 0.0552 | 0.8017 | 1 |
Trypanosoma cruzi | heat shock protein 85, putative | 0.044 | 0.5251 | 0.655 |
Echinococcus multilocularis | heat shock protein | 0.0552 | 0.8017 | 1 |
Schistosoma mansoni | heat shock protein | 0.0552 | 0.8017 | 1 |
Leishmania major | heat shock protein 83-1 | 0.0552 | 0.8017 | 1 |
Trypanosoma brucei | Heat shock protein 83, putative | 0.0552 | 0.8017 | 1 |
Leishmania major | heat shock protein 83-1 | 0.0552 | 0.8017 | 1 |
Entamoeba histolytica | heat shock protein 90, putative | 0.0552 | 0.8017 | 1 |
Trypanosoma brucei | heat shock protein, putative | 0.0552 | 0.8017 | 1 |
Plasmodium falciparum | heat shock protein 90 | 0.0552 | 0.8017 | 1 |
Echinococcus multilocularis | heat shock protein 90 | 0.044 | 0.5251 | 0.655 |
Plasmodium falciparum | endoplasmin, putative | 0.0339 | 0.2766 | 0.345 |
Echinococcus granulosus | endoplasmin | 0.044 | 0.5251 | 0.655 |
Leishmania major | heat shock protein 83-1 | 0.0552 | 0.8017 | 1 |
Trypanosoma brucei | heat shock protein, putative | 0.0552 | 0.8017 | 1 |
Leishmania major | heat shock protein 83-1 | 0.0552 | 0.8017 | 1 |
Leishmania major | heat shock protein 83-1 | 0.0552 | 0.8017 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.