Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Onchocerca volvulus | 0.0459 | 0 | 0.5 | |
Loa Loa (eye worm) | Carm1-pending protein | 0.0504 | 1 | 0.5 |
Toxoplasma gondii | histone arginine methyltransferase PRMT4/CARM1 | 0.0504 | 1 | 0.5 |
Echinococcus multilocularis | histone arginine methyltransferase CARMER | 0.0504 | 1 | 0.5 |
Schistosoma mansoni | protein arginine n-methyltransferase | 0.0504 | 1 | 0.5 |
Echinococcus granulosus | histone arginine methyltransferase CARMER | 0.0504 | 1 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.