Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | tyrosine protein phosphatase non receptor type | 0.105 | 1 | 1 |
Trypanosoma cruzi | trans-sialidase, Group I, putative | 0.0266 | 0.1905 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.1025 | 0.9735 | 1 |
Schistosoma mansoni | protein tyrosine phosphatase non-receptor type nt1 | 0.105 | 1 | 1 |
Trypanosoma cruzi | trans-sialidase, Group I, putative | 0.0266 | 0.1905 | 1 |
Trypanosoma cruzi | trans-sialidase, Group I, putative | 0.0266 | 0.1905 | 1 |
Trypanosoma brucei | trans-sialidase, putative | 0.0266 | 0.1905 | 0.5 |
Trypanosoma brucei | trans-sialidase, putative | 0.0266 | 0.1905 | 0.5 |
Chlamydia trachomatis | ATP-dependent Clp protease proteolytic subunit | 0.0082 | 0 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0178 | 0.0989 | 0.0989 |
Trichomonas vaginalis | Sialidase-1 precursor, putative | 0.1025 | 0.9735 | 1 |
Chlamydia trachomatis | ATP-dependent Clp protease proteolytic subunit | 0.0082 | 0 | 0.5 |
Trypanosoma cruzi | trans-sialidase, Group I, putative | 0.0266 | 0.1905 | 1 |
Trypanosoma cruzi | trans-sialidase, Group I, putative | 0.0266 | 0.1905 | 1 |
Toxoplasma gondii | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein | 0.0082 | 0 | 0.5 |
Trypanosoma brucei | trans-sialidase | 0.0266 | 0.1905 | 0.5 |
Toxoplasma gondii | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein | 0.0082 | 0 | 0.5 |
Loa Loa (eye worm) | protein-tyrosine phosphatase | 0.105 | 1 | 1 |
Plasmodium falciparum | ATP-dependent Clp protease proteolytic subunit | 0.0082 | 0 | 0.5 |
Trypanosoma cruzi | trans-sialidase, putative | 0.0266 | 0.1905 | 1 |
Mycobacterium leprae | PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) | 0.0082 | 0 | 0.5 |
Treponema pallidum | ATP-dependent Clp protease proteolytic subunit | 0.0082 | 0 | 0.5 |
Echinococcus multilocularis | tyrosine protein phosphatase non receptor type | 0.105 | 1 | 1 |
Trypanosoma cruzi | trans-sialidase, Group I, putative | 0.0266 | 0.1905 | 1 |
Trypanosoma cruzi | trans-sialidase, Group I, putative | 0.0266 | 0.1905 | 1 |
Echinococcus multilocularis | geminin | 0.0178 | 0.0989 | 0.0989 |
Trypanosoma cruzi | trans-sialidase, putative | 0.0266 | 0.1905 | 1 |
Plasmodium vivax | ATP-dependent Clp protease proteolytic subunit, putative | 0.0082 | 0 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0178 | 0.0989 | 0.0989 |
Echinococcus granulosus | geminin | 0.0178 | 0.0989 | 0.0989 |
Trypanosoma cruzi | trans-sialidase, Group I, putative | 0.0266 | 0.1905 | 1 |
Trypanosoma brucei | trans-sialidase, putative | 0.0266 | 0.1905 | 0.5 |
Mycobacterium ulcerans | ATP-dependent Clp protease proteolytic subunit | 0.0082 | 0 | 0.5 |
Trypanosoma brucei | trans-sialidase, putative | 0.0266 | 0.1905 | 0.5 |
Trypanosoma cruzi | trans-sialidase, Group I, putative | 0.0266 | 0.1905 | 1 |
Trypanosoma cruzi | trans-sialidase, putative | 0.0266 | 0.1905 | 1 |
Trypanosoma brucei | trans-sialidase, putative | 0.0266 | 0.1905 | 0.5 |
Trypanosoma cruzi | trans-sialidase, Group I, putative | 0.0266 | 0.1905 | 1 |
Mycobacterium ulcerans | ATP-dependent Clp protease proteolytic subunit | 0.0082 | 0 | 0.5 |
Trypanosoma cruzi | trans-sialidase, Group I, putative | 0.0266 | 0.1905 | 1 |
Wolbachia endosymbiont of Brugia malayi | ATP-dependent Clp protease proteolytic subunit | 0.0082 | 0 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.