Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Treponema pallidum | polypeptide deformylase (def) | 0.0264 | 0.2884 | 0.5 |
Entamoeba histolytica | ribokinase, putative | 0.0032 | 0 | 0.5 |
Brugia malayi | Cytochrome P450 family protein | 0.0062 | 0.0379 | 0.0379 |
Entamoeba histolytica | fructokinase, putative | 0.0032 | 0 | 0.5 |
Mycobacterium tuberculosis | Probable polypeptide deformylase Def (PDF) (formylmethionine deformylase) | 0.0264 | 0.2884 | 1 |
Echinococcus multilocularis | pseudouridine metabolizing bifunctional protein | 0.0032 | 0 | 0.5 |
Schistosoma mansoni | ribokinase | 0.0032 | 0 | 0.5 |
Onchocerca volvulus | 0.0835 | 1 | 1 | |
Entamoeba histolytica | tagatose-6-phosphate kinase, putative | 0.0032 | 0 | 0.5 |
Echinococcus multilocularis | ribokinase | 0.0032 | 0 | 0.5 |
Echinococcus multilocularis | adenosine kinase | 0.0032 | 0 | 0.5 |
Trichomonas vaginalis | ribokinase, putative | 0.0032 | 0 | 0.5 |
Echinococcus granulosus | pseudouridine metabolizing bifunctional protein | 0.0032 | 0 | 0.5 |
Mycobacterium ulcerans | peptide deformylase | 0.0264 | 0.2884 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0032 | 0 | 0.5 |
Entamoeba histolytica | Hypothetical protein T24C12.3, putative | 0.0032 | 0 | 0.5 |
Plasmodium falciparum | peptide deformylase | 0.0264 | 0.2884 | 0.5 |
Chlamydia trachomatis | peptide deformylase | 0.0264 | 0.2884 | 0.5 |
Toxoplasma gondii | hypothetical protein | 0.0264 | 0.2884 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0835 | 1 | 1 |
Trypanosoma cruzi | Peptide deformylase 2, putative | 0.0101 | 0.0854 | 1 |
Mycobacterium leprae | PROBABLE POLYPEPTIDE DEFORMYLASE DEF (PDF) (FORMYLMETHIONINE DEFORMYLASE) | 0.0264 | 0.2884 | 1 |
Trypanosoma brucei | Polypeptide deformylase 1 | 0.0101 | 0.0854 | 1 |
Schistosoma mansoni | adenosine kinase | 0.0032 | 0 | 0.5 |
Trypanosoma brucei | Peptide deformylase 2 | 0.0101 | 0.0854 | 1 |
Trichomonas vaginalis | ribokinase, putative | 0.0032 | 0 | 0.5 |
Plasmodium vivax | peptide deformylase, putative | 0.0264 | 0.2884 | 0.5 |
Echinococcus granulosus | adenosine kinase | 0.0032 | 0 | 0.5 |
Leishmania major | polypeptide deformylase-like protein, putative | 0.0101 | 0.0854 | 1 |
Trypanosoma cruzi | polypeptide deformylase-like protein, putative | 0.0101 | 0.0854 | 1 |
Trichomonas vaginalis | ribokinase, putative | 0.0032 | 0 | 0.5 |
Trypanosoma cruzi | Peptide deformylase 2, putative | 0.0101 | 0.0854 | 1 |
Echinococcus granulosus | ribokinase | 0.0032 | 0 | 0.5 |
Entamoeba histolytica | kinase, PfkB family | 0.0032 | 0 | 0.5 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0062 | 0.0379 | 0.0379 |
Schistosoma mansoni | adenosine kinase | 0.0032 | 0 | 0.5 |
Giardia lamblia | Ribokinase | 0.0032 | 0 | 0.5 |
Wolbachia endosymbiont of Brugia malayi | peptide deformylase | 0.0264 | 0.2884 | 0.5 |
Trypanosoma cruzi | polypeptide deformylase-like protein, putative | 0.0101 | 0.0854 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.