Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Cathepsin L-like precursor | 0.0158 | 0.0706 | 0.0706 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0158 | 0.0706 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0158 | 0.0706 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0158 | 0.0706 | 0.8189 |
Loa Loa (eye worm) | cathepsin B | 0.0174 | 0.0862 | 0.1752 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0158 | 0.0706 | 0.8189 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.011 | 0.0225 | 0.0582 |
Onchocerca volvulus | 0.0158 | 0.0706 | 1 | |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0158 | 0.0706 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0158 | 0.0706 | 0.0706 |
Onchocerca volvulus | 0.0158 | 0.0706 | 1 | |
Plasmodium vivax | vivapain-2 | 0.0158 | 0.0706 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0158 | 0.0706 | 0.0706 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0158 | 0.0706 | 0.8189 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.011 | 0.0225 | 0.2606 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0158 | 0.0706 | 0.1828 |
Onchocerca volvulus | 0.0158 | 0.0706 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0174 | 0.0862 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0158 | 0.0706 | 0.8189 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0158 | 0.0706 | 0.1828 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0174 | 0.0862 | 0.2232 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0158 | 0.0706 | 0.8189 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0158 | 0.0706 | 0.8189 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0158 | 0.0706 | 0.8189 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0158 | 0.0706 | 0.8189 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0158 | 0.0706 | 0.1828 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0158 | 0.0706 | 0.8189 |
Onchocerca volvulus | 0.0158 | 0.0706 | 1 | |
Brugia malayi | Papain family cysteine protease containing protein | 0.0158 | 0.0706 | 0.0706 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0158 | 0.0706 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0158 | 0.0706 | 0.1828 |
Brugia malayi | cathepsin L-like precursor | 0.011 | 0.0225 | 0.0225 |
Loa Loa (eye worm) | fibroinase | 0.0158 | 0.0706 | 0.1323 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0158 | 0.0706 | 0.1828 |
Loa Loa (eye worm) | cysteine protease | 0.0158 | 0.0706 | 0.1323 |
Onchocerca volvulus | Cathepsin L homolog | 0.0158 | 0.0706 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0158 | 0.0706 | 0.8189 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0158 | 0.0706 | 0.8189 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0158 | 0.0706 | 0.1828 |
Loa Loa (eye worm) | hypothetical protein | 0.0473 | 0.3864 | 1 |
Echinococcus granulosus | cathepsin l1 | 0.011 | 0.0225 | 0.0582 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0158 | 0.0706 | 0.8189 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0158 | 0.0706 | 0.1828 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0158 | 0.0706 | 0.8189 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0174 | 0.0862 | 0.2232 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0158 | 0.0706 | 0.8189 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0158 | 0.0706 | 0.8189 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0158 | 0.0706 | 0.8189 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0158 | 0.0706 | 0.8189 |
Echinococcus granulosus | cathepsin l1 | 0.0158 | 0.0706 | 0.1828 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0158 | 0.0706 | 0.1828 |
Leishmania major | cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like | 0.0174 | 0.0862 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0158 | 0.0706 | 0.8189 |
Giardia lamblia | Cathepsin B precursor | 0.0174 | 0.0862 | 0.5 |
Echinococcus multilocularis | cysteine protease | 0.0158 | 0.0706 | 0.1828 |
Brugia malayi | Cathepsin L-like precursor | 0.011 | 0.0225 | 0.0225 |
Echinococcus multilocularis | cysteine protease | 0.0158 | 0.0706 | 0.1828 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0158 | 0.0706 | 0.1828 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0158 | 0.0706 | 0.8189 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.011 | 0.0225 | 0.0225 |
Brugia malayi | Cathepsin L-like precursor | 0.0158 | 0.0706 | 0.0706 |
Brugia malayi | cathepsin B-like cysteine proteinase | 0.0473 | 0.3864 | 0.3864 |
Brugia malayi | Cathepsin L-like precursor | 0.0158 | 0.0706 | 0.0706 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.011 | 0.0225 | 0.2606 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0473 | 0.3864 | 1 |
Trypanosoma brucei | cysteine peptidase C (CPC) | 0.0174 | 0.0862 | 1 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0158 | 0.0706 | 0.1323 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0158 | 0.0706 | 0.8189 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0158 | 0.0706 | 0.8189 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0158 | 0.0706 | 0.1828 |
Onchocerca volvulus | 0.0158 | 0.0706 | 1 | |
Echinococcus granulosus | cathepsin b | 0.0473 | 0.3864 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0473 | 0.3864 | 1 |
Echinococcus multilocularis | cathepsin b | 0.0473 | 0.3864 | 1 |
Plasmodium vivax | vivapain-2 | 0.0158 | 0.0706 | 1 |
Echinococcus multilocularis | cathepsin b | 0.0473 | 0.3864 | 1 |
Echinococcus granulosus | cathepsin b | 0.0473 | 0.3864 | 1 |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.0473 | 0.3864 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0158 | 0.0706 | 0.8189 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0158 | 0.0706 | 0.8189 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0473 | 0.3864 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0158 | 0.0706 | 0.8189 |
Loa Loa (eye worm) | hypothetical protein | 0.0158 | 0.0706 | 0.1323 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0158 | 0.0706 | 0.8189 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0158 | 0.0706 | 0.8189 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0158 | 0.0706 | 0.1828 |
Toxoplasma gondii | cathepsin B | 0.0174 | 0.0862 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0158 | 0.0706 | 0.8189 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0158 | 0.0706 | 0.1828 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0473 | 0.3864 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0158 | 0.0706 | 0.8189 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0158 | 0.0706 | 0.8189 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0158 | 0.0706 | 0.8189 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0158 | 0.0706 | 0.8189 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0158 | 0.0706 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.011 | 0.0225 | 0.0582 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0158 | 0.0706 | 0.1323 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0158 | 0.0706 | 0.8189 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0158 | 0.0706 | 0.8189 |
Onchocerca volvulus | Cathepsin F homolog | 0.0158 | 0.0706 | 1 |
Giardia lamblia | Cathepsin B precursor | 0.0174 | 0.0862 | 0.5 |
Onchocerca volvulus | 0.0158 | 0.0706 | 1 | |
Brugia malayi | Cathepsin L-like precursor | 0.0158 | 0.0706 | 0.0706 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0158 | 0.0706 | 0.8189 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0158 | 0.0706 | 0.8189 |
Onchocerca volvulus | 0.0158 | 0.0706 | 1 | |
Giardia lamblia | Cathepsin B precursor | 0.0174 | 0.0862 | 0.5 |
Loa Loa (eye worm) | ctsf protein | 0.0158 | 0.0706 | 0.1323 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0158 | 0.0706 | 0.8189 |
Entamoeba histolytica | cysteine proteinase, putative | 0.011 | 0.0225 | 0.3182 |
Onchocerca volvulus | Cathepsin L homolog | 0.0158 | 0.0706 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0158 | 0.0706 | 0.1828 |
Entamoeba histolytica | cysteine protease, putative | 0.0158 | 0.0706 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.011 | 0.0225 | 0.0225 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.