Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0361 | 0.8291 | 0.956 |
Echinococcus multilocularis | cAMP specific 3',5' cyclic phosphodiesterase | 0.0361 | 0.8291 | 0.8291 |
Brugia malayi | Hemopexin family protein | 0.0133 | 0.0438 | 0.0646 |
Echinococcus granulosus | cAMP specific 3'5' cyclic phosphodiesterase | 0.0317 | 0.6779 | 0.6779 |
Echinococcus granulosus | cAMP specific 3'5' cyclic phosphodiesterase | 0.0361 | 0.8291 | 0.8291 |
Brugia malayi | Probable 3',5'-cyclic phosphodiesterase R153.1, putative | 0.0317 | 0.6779 | 1 |
Echinococcus multilocularis | cAMP specific 3',5' cyclic phosphodiesterase | 0.0317 | 0.6779 | 0.6779 |
Echinococcus granulosus | cAMP specific 3'5' cyclic phosphodiesterase | 0.0361 | 0.8291 | 0.8291 |
Loa Loa (eye worm) | bone morphogenetic protein 1b | 0.0373 | 0.8672 | 1 |
Brugia malayi | Matrixin family protein | 0.0297 | 0.6077 | 0.8965 |
Echinococcus multilocularis | cAMP specific 3',5' cyclic phosphodiesterase | 0.0361 | 0.8291 | 0.8291 |
Schistosoma mansoni | subfamily M12A unassigned peptidase (M12 family) | 0.0373 | 0.8672 | 1 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.0361 | 0.8291 | 1 |
Echinococcus multilocularis | matrix metallopeptidase 7 (M10 family) | 0.0411 | 1 | 1 |
Echinococcus multilocularis | Tolloid protein 1 | 0.0373 | 0.8672 | 0.8672 |
Loa Loa (eye worm) | matrixin family protein | 0.0208 | 0.3015 | 0.3476 |
Loa Loa (eye worm) | hypothetical protein | 0.0152 | 0.1085 | 0.1252 |
Onchocerca volvulus | Matrilysin homolog | 0.0278 | 0.5433 | 1 |
Loa Loa (eye worm) | AStacin protease | 0.0233 | 0.3875 | 0.4468 |
Loa Loa (eye worm) | cyclic AMP specific phosphodiesterase PDE4D5A | 0.0317 | 0.6779 | 0.7817 |
Echinococcus granulosus | Tolloid protein 1 | 0.0373 | 0.8672 | 0.8672 |
Schistosoma mansoni | matrix metallopeptidase-7 (M10 family) | 0.0164 | 0.1511 | 0.1303 |
Giardia lamblia | CAMP-specific 3,5-cyclic phosphodiesterase 4B | 0.0361 | 0.8291 | 0.5 |
Onchocerca volvulus | Matrix metalloproteinase homolog | 0.0208 | 0.3015 | 0.5158 |
Loa Loa (eye worm) | hypothetical protein | 0.0357 | 0.8152 | 0.94 |
Schistosoma mansoni | camp-specific 35-cyclic phosphodiesterase | 0.0361 | 0.8291 | 0.9537 |
Loa Loa (eye worm) | hypothetical protein | 0.0164 | 0.1511 | 0.1742 |
Loa Loa (eye worm) | matrixin family protein | 0.0297 | 0.6077 | 0.7008 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.