Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Plasmodium falciparum | peptidase, putative | 0.0402 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.1034 | 0.2792 | 0.2872 |
Trypanosoma cruzi | oligopeptidase B-like protein, putative | 0.0632 | 0.1018 | 0.1309 |
Echinococcus granulosus | prolyl endopeptidase | 0.1107 | 0.3112 | 0.3112 |
Toxoplasma gondii | dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein | 0.1436 | 0.4565 | 1 |
Plasmodium vivax | hypothetical protein, conserved | 0.0402 | 0 | 0.5 |
Trypanosoma cruzi | dipeptidyl-peptidase 8-like serine peptidase | 0.2164 | 0.7776 | 1 |
Brugia malayi | prolyl oligopeptidase family protein | 0.1107 | 0.3112 | 0.3202 |
Trichomonas vaginalis | Clan SC, family S33, methylesterase-like serine peptidase | 0.0402 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.1107 | 0.3112 | 0.3202 |
Trypanosoma brucei | serine peptidase, Clan SC, Family S9B | 0.2164 | 0.7776 | 1 |
Onchocerca volvulus | Dipeptidyl peptidase family member 1 homolog | 0.2604 | 0.972 | 1 |
Leishmania major | prolyl oligopeptidase, putative,serine peptidase clan SC, family S9A, putative | 0.1107 | 0.3112 | 0.3098 |
Mycobacterium tuberculosis | Probable protease II PtrBa [first part] (oligopeptidase B) | 0.0705 | 0.1339 | 1 |
Brugia malayi | prolyl oligopeptidase family protein | 0.2164 | 0.7776 | 0.8 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0402 | 0 | 0.5 |
Entamoeba histolytica | prolyl oligopeptidase family protein | 0.0402 | 0 | 0.5 |
Trypanosoma cruzi | oligopeptidase b | 0.0632 | 0.1018 | 0.1309 |
Trichomonas vaginalis | Clan SC, family S9, acylaminoacyl-peptidase-like serine peptidase | 0.0402 | 0 | 0.5 |
Leishmania major | dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B | 0.2164 | 0.7776 | 1 |
Trypanosoma cruzi | oligopeptidase b | 0.0632 | 0.1018 | 0.1309 |
Echinococcus granulosus | dipeptidyl aminopeptidaseprotein | 0.2604 | 0.972 | 0.972 |
Echinococcus multilocularis | dipeptidyl aminopeptidaseprotein | 0.2604 | 0.972 | 0.972 |
Echinococcus multilocularis | Lysosomal Pro X carboxypeptidase | 0.2667 | 1 | 1 |
Brugia malayi | prolyl oligopeptidase family protein | 0.2604 | 0.972 | 1 |
Schistosoma mansoni | prolyl oligopeptidase (S09 family) | 0.1107 | 0.3112 | 0.3112 |
Mycobacterium leprae | PROBABLE PROTEASE II PTRBB (OLIGOPEPTIDASE B) | 0.0632 | 0.1018 | 0.5 |
Echinococcus multilocularis | Dipeptidyl peptidase 9 | 0.2164 | 0.7776 | 0.7776 |
Trypanosoma brucei | Dipeptidyl-peptidase 8-like, putative | 0.2164 | 0.7776 | 1 |
Echinococcus granulosus | Dipeptidyl peptidase 9 | 0.2164 | 0.7776 | 0.7776 |
Schistosoma mansoni | dipeptidyl-peptidase 9 (S09 family) | 0.2164 | 0.7776 | 0.7776 |
Entamoeba histolytica | dipeptidyl-peptidase, putative | 0.0402 | 0 | 0.5 |
Trypanosoma cruzi | serine peptidase, clan SC, family S9A-like protein, putative | 0.0632 | 0.1018 | 0.1309 |
Loa Loa (eye worm) | hypothetical protein | 0.1129 | 0.3212 | 0.3304 |
Entamoeba histolytica | dipeptidyl-peptidase, putative | 0.0402 | 0 | 0.5 |
Trypanosoma cruzi | serine peptidase, Clan SC, Family S9B | 0.2164 | 0.7776 | 1 |
Schistosoma mansoni | prolyl oligopeptidase (S09 family) | 0.1107 | 0.3112 | 0.3112 |
Entamoeba histolytica | prolyl oligopeptidase family protein | 0.0402 | 0 | 0.5 |
Entamoeba histolytica | prolyl oligopeptidase family protein | 0.0402 | 0 | 0.5 |
Mycobacterium ulcerans | protease II (oligopeptidase B), PtrB | 0.0632 | 0.1018 | 0.5 |
Schistosoma mansoni | subfamily S9B unassigned peptidase (S09 family) | 0.2604 | 0.972 | 0.972 |
Echinococcus multilocularis | prolyl endopeptidase | 0.1107 | 0.3112 | 0.3112 |
Trypanosoma cruzi | prolyl endopeptidase | 0.1107 | 0.3112 | 0.4002 |
Trypanosoma brucei | prolyl endopeptidase | 0.1107 | 0.3112 | 0.4002 |
Giardia lamblia | Alanyl dipeptidyl peptidase | 0.0402 | 0 | 0.5 |
Entamoeba histolytica | hypothetical protein, conserved | 0.0402 | 0 | 0.5 |
Trypanosoma brucei | oligopeptidase b | 0.0632 | 0.1018 | 0.1309 |
Toxoplasma gondii | prolyl endopeptidase | 0.1107 | 0.3112 | 0.6818 |
Giardia lamblia | Alanyl dipeptidyl peptidase | 0.0402 | 0 | 0.5 |
Loa Loa (eye worm) | prolyl oligopeptidase | 0.2604 | 0.972 | 1 |
Trypanosoma brucei | serine peptidase, clan SC, family S9A-like protein | 0.0632 | 0.1018 | 0.1309 |
Trypanosoma brucei | prolyl oligopeptidase, putative | 0.0632 | 0.1018 | 0.1309 |
Schistosoma mansoni | family S28 unassigned peptidase (S28 family) | 0.2667 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.1034 | 0.2792 | 0.2872 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.