Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Plasmodium vivax | vivapain-2 | 0.0334 | 0.2055 | 1 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.062 | 0.6199 | 0.6199 |
Loa Loa (eye worm) | cysteine protease | 0.0334 | 0.2055 | 0.1499 |
Echinococcus granulosus | cathepsin l1 | 0.0237 | 0.0654 | 0.0654 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0334 | 0.2055 | 0.4506 |
Brugia malayi | Cathepsin L-like precursor | 0.0334 | 0.2055 | 0.2055 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0717 | 0.76 | 1 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0334 | 0.2055 | 0.1499 |
Echinococcus multilocularis | cathepsin b | 0.0882 | 1 | 1 |
Leishmania major | cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like | 0.0507 | 0.456 | 0.4518 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0334 | 0.2055 | 0.4506 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0334 | 0.2055 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0237 | 0.0654 | 0.3182 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0334 | 0.2055 | 1 |
Loa Loa (eye worm) | ctsf protein | 0.0334 | 0.2055 | 0.1499 |
Onchocerca volvulus | 0.0334 | 0.2055 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0334 | 0.2055 | 0.4506 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0334 | 0.2055 | 0.4506 |
Leishmania major | cathepsin L-like protease | 0.0717 | 0.76 | 1 |
Onchocerca volvulus | 0.0334 | 0.2055 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0334 | 0.2055 | 0.4506 |
Brugia malayi | Cathepsin L-like precursor | 0.0334 | 0.2055 | 0.2055 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0334 | 0.2055 | 0.2055 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0334 | 0.2055 | 0.4506 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0334 | 0.2055 | 0.2055 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0717 | 0.76 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0334 | 0.2055 | 0.4506 |
Echinococcus granulosus | cathepsin b | 0.0882 | 1 | 1 |
Echinococcus granulosus | cathepsin b | 0.0882 | 1 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0882 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0334 | 0.2055 | 0.4506 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0882 | 1 | 1 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0507 | 0.456 | 0.456 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0717 | 0.76 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0334 | 0.2055 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0334 | 0.2055 | 0.4506 |
Brugia malayi | Cathepsin L-like precursor | 0.0237 | 0.0654 | 0.0654 |
Onchocerca volvulus | 0.0334 | 0.2055 | 1 | |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.0882 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0334 | 0.2055 | 0.4506 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0717 | 0.76 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0334 | 0.2055 | 0.4506 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0237 | 0.0654 | 0.0654 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0717 | 0.76 | 0.76 |
Onchocerca volvulus | 0.0334 | 0.2055 | 1 | |
Giardia lamblia | Cathepsin B precursor | 0.0507 | 0.456 | 0.5 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0717 | 0.76 | 1 |
Onchocerca volvulus | 0.0334 | 0.2055 | 1 | |
Brugia malayi | Papain family cysteine protease containing protein | 0.0334 | 0.2055 | 0.2055 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0882 | 1 | 1 |
Onchocerca volvulus | 0.0334 | 0.2055 | 1 | |
Echinococcus multilocularis | cathepsin b | 0.0882 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0717 | 0.76 | 1 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0882 | 1 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0507 | 0.456 | 0.456 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0334 | 0.2055 | 0.4506 |
Brugia malayi | Cathepsin L-like precursor | 0.0334 | 0.2055 | 0.2055 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0717 | 0.76 | 0.76 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0507 | 0.456 | 1 |
Giardia lamblia | Cathepsin B precursor | 0.0507 | 0.456 | 0.5 |
Entamoeba histolytica | cysteine protease, putative | 0.0334 | 0.2055 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0882 | 1 | 1 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0334 | 0.2055 | 0.2055 |
Giardia lamblia | Cathepsin B precursor | 0.0507 | 0.456 | 0.5 |
Loa Loa (eye worm) | fibroinase | 0.0334 | 0.2055 | 0.1499 |
Brugia malayi | Cathepsin L-like precursor | 0.0334 | 0.2055 | 0.2055 |
Brugia malayi | Cathepsin L-like precursor | 0.0334 | 0.2055 | 0.2055 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0334 | 0.2055 | 0.4506 |
Brugia malayi | Cathepsin L-like precursor | 0.0237 | 0.0654 | 0.0654 |
Onchocerca volvulus | Cathepsin L homolog | 0.0334 | 0.2055 | 1 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0334 | 0.2055 | 0.2055 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0334 | 0.2055 | 0.4506 |
Onchocerca volvulus | 0.0334 | 0.2055 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0334 | 0.2055 | 0.4506 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0334 | 0.2055 | 0.2055 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0717 | 0.76 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0334 | 0.2055 | 0.2055 |
Brugia malayi | cathepsin L-like precursor | 0.0237 | 0.0654 | 0.0654 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0717 | 0.76 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0334 | 0.2055 | 0.4506 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0237 | 0.0654 | 0.0654 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0334 | 0.2055 | 0.4506 |
Leishmania major | cathepsin L-like protease | 0.0717 | 0.76 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0334 | 0.2055 | 0.4506 |
Leishmania major | cathepsin L-like protease | 0.0717 | 0.76 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0717 | 0.76 | 1 |
Onchocerca volvulus | Cathepsin L homolog | 0.0334 | 0.2055 | 1 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0334 | 0.2055 | 0.2055 |
Loa Loa (eye worm) | hypothetical protein | 0.0334 | 0.2055 | 0.1499 |
Onchocerca volvulus | Cathepsin F homolog | 0.0334 | 0.2055 | 1 |
Echinococcus multilocularis | cysteine protease | 0.0334 | 0.2055 | 0.2055 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0334 | 0.2055 | 0.4506 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0237 | 0.0654 | 0.1434 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0334 | 0.2055 | 0.4506 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0334 | 0.2055 | 0.2055 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0334 | 0.2055 | 0.4506 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0334 | 0.2055 | 0.4506 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0334 | 0.2055 | 1 |
Trypanosoma cruzi | major cysteine proteinase, putative | 0.0478 | 0.4144 | 0.4144 |
Trypanosoma brucei | cysteine peptidase C (CPC) | 0.0507 | 0.456 | 0.6 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0717 | 0.76 | 0.76 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0334 | 0.2055 | 0.4506 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0237 | 0.0654 | 0.1434 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0334 | 0.2055 | 0.2055 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0334 | 0.2055 | 1 |
Echinococcus multilocularis | cysteine protease | 0.0334 | 0.2055 | 0.2055 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0334 | 0.2055 | 0.4506 |
Loa Loa (eye worm) | cathepsin B | 0.0507 | 0.456 | 0.418 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0717 | 0.76 | 1 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0334 | 0.2055 | 0.1499 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0334 | 0.2055 | 0.4506 |
Toxoplasma gondii | cathepsin B | 0.0507 | 0.456 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0717 | 0.76 | 0.76 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0334 | 0.2055 | 0.2055 |
Echinococcus granulosus | cathepsin l1 | 0.0334 | 0.2055 | 0.2055 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0717 | 0.76 | 1 |
Plasmodium vivax | vivapain-2 | 0.0334 | 0.2055 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.