Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | low-density lipoprotein receptor repeat class B containing protein | 0.0028 | 0 | 0.5 |
Toxoplasma gondii | enoyl-acyl carrier reductase ENR | 0.0186 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0 | 0.5 |
Wolbachia endosymbiont of Brugia malayi | enoyl-ACP reductase | 0.0186 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0 | 0.5 |
Echinococcus granulosus | Tolloid protein 1 | 0.0028 | 0 | 0.5 |
Echinococcus multilocularis | fibrillin 1 | 0.0028 | 0 | 0.5 |
Loa Loa (eye worm) | multiple epidermal growth factor-like domains 6 | 0.0028 | 0 | 0.5 |
Brugia malayi | Low-density lipoprotein receptor repeat class B containing protein | 0.0028 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0 | 0.5 |
Plasmodium falciparum | enoyl-acyl carrier reductase | 0.0186 | 1 | 0.5 |
Trichomonas vaginalis | hypothetical protein | 0.0186 | 1 | 0.5 |
Echinococcus granulosus | laminin | 0.0028 | 0 | 0.5 |
Schistosoma mansoni | egf-like domain protein | 0.0028 | 0 | 0.5 |
Onchocerca volvulus | Arrow homolog | 0.0028 | 0 | 0.5 |
Schistosoma mansoni | subfamily M12A unassigned peptidase (M12 family) | 0.0028 | 0 | 0.5 |
Mycobacterium tuberculosis | NADH-dependent enoyl-[acyl-carrier-protein] reductase InhA (NADH-dependent enoyl-ACP reductase) | 0.0186 | 1 | 0.5 |
Brugia malayi | Calcium binding EGF domain containing protein | 0.0028 | 0 | 0.5 |
Mycobacterium ulcerans | enoyl-(acyl carrier protein) reductase | 0.0186 | 1 | 0.5 |
Mycobacterium leprae | NADH-DEPENDENT ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE INHA (NADH-DEPENDENT ENOYL-ACP REDUCTASE) | 0.0186 | 1 | 0.5 |
Plasmodium vivax | enoyl-acyl carrier protein reductase | 0.0186 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0 | 0.5 |
Brugia malayi | Fibulin-1 precursor | 0.0028 | 0 | 0.5 |
Echinococcus multilocularis | Tolloid protein 1 | 0.0028 | 0 | 0.5 |
Loa Loa (eye worm) | bone morphogenetic protein 1b | 0.0028 | 0 | 0.5 |
Echinococcus multilocularis | laminin | 0.0028 | 0 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.