Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Mycobacterium leprae | PROBABLE PROTEASE II PTRBB (OLIGOPEPTIDASE B) | 0.0595 | 0.1329 | 0.5 |
Loa Loa (eye worm) | prolyl oligopeptidase | 0.2462 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0429 | 0.0557 | 0.0557 |
Plasmodium falciparum | peptidase, putative | 0.0309 | 0 | 0.5 |
Schistosoma mansoni | subfamily S9B unassigned peptidase (S09 family) | 0.2462 | 1 | 1 |
Trypanosoma cruzi | oligopeptidase b | 0.0595 | 0.1329 | 0.3271 |
Leishmania major | dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B | 0.1099 | 0.3668 | 0.8558 |
Entamoeba histolytica | prolyl oligopeptidase family protein | 0.0309 | 0 | 0.5 |
Trichomonas vaginalis | Clan SC, family S9, acylaminoacyl-peptidase-like serine peptidase | 0.0309 | 0 | 0.5 |
Echinococcus multilocularis | Dipeptidyl peptidase 9 | 0.1099 | 0.3668 | 0.3668 |
Trypanosoma cruzi | dipeptidyl-peptidase 8-like serine peptidase | 0.1099 | 0.3668 | 0.903 |
Brugia malayi | hypothetical protein | 0.067 | 0.1676 | 0.1676 |
Echinococcus multilocularis | dipeptidyl aminopeptidaseprotein | 0.2462 | 1 | 1 |
Entamoeba histolytica | dipeptidyl-peptidase, putative | 0.0309 | 0 | 0.5 |
Trypanosoma cruzi | oligopeptidase b | 0.0595 | 0.1329 | 0.3271 |
Entamoeba histolytica | prolyl oligopeptidase family protein | 0.0309 | 0 | 0.5 |
Trypanosoma brucei | serine peptidase, Clan SC, Family S9B | 0.1099 | 0.3668 | 0.903 |
Loa Loa (eye worm) | hypothetical protein | 0.1184 | 0.4062 | 0.4062 |
Entamoeba histolytica | prolyl oligopeptidase family protein | 0.0309 | 0 | 0.5 |
Trypanosoma cruzi | oligopeptidase B-like protein, putative | 0.0595 | 0.1329 | 0.3271 |
Echinococcus granulosus | Dipeptidyl peptidase 9 | 0.1099 | 0.3668 | 0.3668 |
Plasmodium vivax | hypothetical protein, conserved | 0.0309 | 0 | 0.5 |
Schistosoma mansoni | prolyl oligopeptidase (S09 family) | 0.1184 | 0.4062 | 0.4062 |
Echinococcus granulosus | prolyl endopeptidase | 0.1184 | 0.4062 | 0.4062 |
Brugia malayi | prolyl oligopeptidase family protein | 0.1184 | 0.4062 | 0.4062 |
Schistosoma mansoni | dipeptidyl-peptidase 9 (S09 family) | 0.1099 | 0.3668 | 0.3668 |
Trypanosoma brucei | oligopeptidase b | 0.0595 | 0.1329 | 0.3271 |
Trichomonas vaginalis | Clan SC, family S33, methylesterase-like serine peptidase | 0.0309 | 0 | 0.5 |
Schistosoma mansoni | prolyl oligopeptidase (S09 family) | 0.1184 | 0.4062 | 0.4062 |
Echinococcus granulosus | dipeptidyl aminopeptidaseprotein | 0.2462 | 1 | 1 |
Onchocerca volvulus | Dipeptidyl peptidase family member 1 homolog | 0.2462 | 1 | 1 |
Toxoplasma gondii | prolyl endopeptidase | 0.1184 | 0.4062 | 1 |
Trypanosoma brucei | prolyl oligopeptidase, putative | 0.0595 | 0.1329 | 0.3271 |
Trypanosoma brucei | prolyl endopeptidase | 0.1184 | 0.4062 | 1 |
Trypanosoma cruzi | serine peptidase, clan SC, family S9A-like protein, putative | 0.0595 | 0.1329 | 0.3271 |
Entamoeba histolytica | dipeptidyl-peptidase, putative | 0.0309 | 0 | 0.5 |
Trypanosoma brucei | serine peptidase, clan SC, family S9A-like protein | 0.0595 | 0.1329 | 0.3271 |
Giardia lamblia | Alanyl dipeptidyl peptidase | 0.0309 | 0 | 0.5 |
Trypanosoma brucei | Dipeptidyl-peptidase 8-like, putative | 0.1099 | 0.3668 | 0.903 |
Toxoplasma gondii | dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein | 0.0979 | 0.3112 | 0.766 |
Trypanosoma cruzi | prolyl endopeptidase | 0.1184 | 0.4062 | 1 |
Echinococcus multilocularis | prolyl endopeptidase | 0.1184 | 0.4062 | 0.4062 |
Mycobacterium tuberculosis | Probable protease II PtrBa [first part] (oligopeptidase B) | 0.0875 | 0.2626 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.067 | 0.1676 | 0.1676 |
Leishmania major | prolyl oligopeptidase, putative,serine peptidase clan SC, family S9A, putative | 0.1184 | 0.4062 | 1 |
Entamoeba histolytica | hypothetical protein, conserved | 0.0309 | 0 | 0.5 |
Brugia malayi | prolyl oligopeptidase family protein | 0.1099 | 0.3668 | 0.3668 |
Trypanosoma cruzi | serine peptidase, Clan SC, Family S9B | 0.1099 | 0.3668 | 0.903 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0309 | 0 | 0.5 |
Mycobacterium ulcerans | protease II (oligopeptidase B), PtrB | 0.0595 | 0.1329 | 0.5 |
Giardia lamblia | Alanyl dipeptidyl peptidase | 0.0309 | 0 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.