Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Plasmodium falciparum | hexose transporter | 0.0125 | 1 | 0.5 |
Echinococcus granulosus | solute carrier family 2 facilitated glucose | 0.0125 | 1 | 1 |
Trypanosoma cruzi | hexose transporter, putative | 0.0039 | 0 | 0.5 |
Trypanosoma brucei | THT1 - hexose transporter, putative | 0.0039 | 0 | 0.5 |
Leishmania major | glucose transporter/membrane transporter D2, putative | 0.0039 | 0 | 0.5 |
Trypanosoma cruzi | hexose transporter, putative | 0.0039 | 0 | 0.5 |
Echinococcus multilocularis | solute carrier family 2, facilitated glucose | 0.0125 | 1 | 1 |
Trypanosoma cruzi | hexose transporter, putative | 0.0039 | 0 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0125 | 1 | 1 |
Trypanosoma cruzi | hexose transporter | 0.0039 | 0 | 0.5 |
Echinococcus multilocularis | solute carrier family 2 facilitated glucose | 0.0125 | 1 | 1 |
Echinococcus granulosus | solute carrier family 2 facilitated glucose | 0.0125 | 1 | 1 |
Trypanosoma brucei | glucose transporter 2A | 0.0039 | 0 | 0.5 |
Trypanosoma brucei | glucose transporter, putative | 0.0039 | 0 | 0.5 |
Trypanosoma brucei | glucose transporter, putative | 0.0039 | 0 | 0.5 |
Schistosoma mansoni | glucose transport protein | 0.0125 | 1 | 0.5 |
Trypanosoma brucei | THT1 - hexose transporter, putative | 0.0039 | 0 | 0.5 |
Trypanosoma brucei | glucose transporter, putative | 0.0039 | 0 | 0.5 |
Trypanosoma brucei | glucose transporter, putative | 0.0039 | 0 | 0.5 |
Loa Loa (eye worm) | sugar transporter | 0.0125 | 1 | 0.5 |
Leishmania major | glucose transporter, lmgt1 | 0.0039 | 0 | 0.5 |
Echinococcus multilocularis | solute carrier family 2 facilitated glucose | 0.0125 | 1 | 1 |
Schistosoma mansoni | glucose transport protein | 0.0125 | 1 | 0.5 |
Echinococcus multilocularis | solute carrier family 2 facilitated glucose | 0.0125 | 1 | 1 |
Trypanosoma brucei | glucose transporter 1E | 0.0039 | 0 | 0.5 |
Plasmodium vivax | hexose transporter | 0.0125 | 1 | 0.5 |
Echinococcus granulosus | solute carrier family 2 facilitated glucose | 0.0125 | 1 | 1 |
Trypanosoma brucei | glucose transporter, putative | 0.0039 | 0 | 0.5 |
Trypanosoma brucei | glucose transporter, putative | 0.0039 | 0 | 0.5 |
Toxoplasma gondii | facilitative glucose transporter GT1 | 0.0125 | 1 | 0.5 |
Leishmania major | glucose transporter, lmgt3 | 0.0039 | 0 | 0.5 |
Leishmania major | glucose transporter, lmgt2 | 0.0039 | 0 | 0.5 |
Trypanosoma brucei | glucose transporter, putative | 0.0039 | 0 | 0.5 |
Echinococcus granulosus | solute carrier family 2 facilitated glucose | 0.0125 | 1 | 1 |
Trypanosoma brucei | THT1 - hexose transporter, putative | 0.0039 | 0 | 0.5 |
Schistosoma mansoni | glucose transport protein | 0.0125 | 1 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0125 | 1 | 0.5 |
Trypanosoma brucei | glucose transporter, putative | 0.0039 | 0 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.