Detailed information for compound 885047

Basic information

Technical information
  • TDR Targets ID: 885047
  • Name: 2-(2-methoxyphenyl)-3-(2-pyridin-2-ylethyl)-1 ,3-thiazolidin-4-one
  • MW: 314.402 | Formula: C17H18N2O2S
  • H donors: 0 H acceptors: 2 LogP: 2.7 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1ccccc1C1SCC(=O)N1CCc1ccccn1
  • InChi: 1S/C17H18N2O2S/c1-21-15-8-3-2-7-14(15)17-19(16(20)12-22-17)11-9-13-6-4-5-10-18-13/h2-8,10,17H,9,11-12H2,1H3
  • InChiKey: VMPOIWLCTIQGCS-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 2-(2-methoxyphenyl)-3-[2-(2-pyridyl)ethyl]thiazolidin-4-one
  • 2-(2-methoxyphenyl)-3-[2-(2-pyridyl)ethyl]-4-thiazolidinone
  • Oprea1_062445

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus g protein coupled receptor 0.0147 0.1775 0.174
Echinococcus multilocularis fmrfamide receptor 0.0147 0.1775 0.174
Brugia malayi hypothetical protein 0.0147 0.1775 0.1647
Loa Loa (eye worm) hypothetical protein 0.0147 0.1775 0.1775
Loa Loa (eye worm) hypothetical protein 0.0072 0.0671 0.0671
Trypanosoma cruzi Peptide deformylase 2, putative 0.0085 0.0868 1
Schistosoma mansoni histamine h1 receptor 0.0147 0.1775 0.174
Brugia malayi hypothetical protein 0.0147 0.1775 0.1647
Brugia malayi Tachykinin-like peptides receptor 99D 0.0147 0.1775 0.1647
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0147 0.1775 0.174
Schistosoma mansoni biogenic amine receptor 0.0147 0.1775 0.174
Schistosoma mansoni alpha-1 adrenergic receptor 0.0147 0.1775 0.174
Schistosoma mansoni neuropeptide receptor 0.0147 0.1775 0.174
Echinococcus granulosus neuropeptide receptor 0.0147 0.1775 0.174
Leishmania major polypeptide deformylase-like protein, putative 0.0085 0.0868 1
Echinococcus multilocularis g protein coupled receptor 0.0147 0.1775 0.174
Schistosoma mansoni voltage-gated potassium channel 0.009 0.0942 0.0903
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0147 0.1775 0.174
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0147 0.1775 0.174
Loa Loa (eye worm) G-protein coupled receptor 0.0147 0.1775 0.1775
Loa Loa (eye worm) hypothetical protein 0.0147 0.1775 0.1775
Loa Loa (eye worm) hypothetical protein 0.0147 0.1775 0.1775
Echinococcus multilocularis ceramide glucosyltransferase 0.0709 1 1
Echinococcus granulosus neuropeptides capa receptor 0.0147 0.1775 0.174
Schistosoma mansoni biogenic amine receptor 0.0147 0.1775 0.174
Echinococcus granulosus tachykinin peptides receptor 99D 0.0147 0.1775 0.174
Echinococcus multilocularis g protein coupled receptor 0.0147 0.1775 0.174
Loa Loa (eye worm) hypothetical protein 0.0147 0.1775 0.1775
Loa Loa (eye worm) ceramide glucosyltransferase 0.0709 1 1
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0147 0.1775 0.1775
Schistosoma mansoni neuropeptide f receptor 76f 0.0147 0.1775 0.174
Mycobacterium leprae PROBABLE POLYPEPTIDE DEFORMYLASE DEF (PDF) (FORMYLMETHIONINE DEFORMYLASE) 0.0224 0.2893 0.5
Schistosoma mansoni opsin-like receptor 0.0147 0.1775 0.174
Giardia lamblia Ceramide glucosyltransferase 0.0321 0.4325 0.5
Echinococcus multilocularis sex peptide receptor 0.0147 0.1775 0.174
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0147 0.1775 0.174
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0147 0.1775 0.174
Brugia malayi hypothetical protein 0.0057 0.0451 0.0302
Echinococcus granulosus 7TM GPCR rhodopsin 0.0147 0.1775 0.174
Loa Loa (eye worm) hypothetical protein 0.0147 0.1775 0.1775
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0083 0.0831 0.0791
Echinococcus granulosus ceramide glucosyltransferase 0.0709 1 1
Schistosoma mansoni ceramide glucosyltransferase 0.0709 1 1
Loa Loa (eye worm) integrin beta-2 0.0362 0.4921 0.4921
Schistosoma mansoni adenoreceptor 0.0147 0.1775 0.174
Trypanosoma cruzi Peptide deformylase 2, putative 0.0085 0.0868 1
Loa Loa (eye worm) hypothetical protein 0.0147 0.1775 0.1775
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 3 0.0032 0.0089 0.0046
Echinococcus multilocularis rhodopsin orphan GPCR 0.0147 0.1775 0.174
Schistosoma mansoni opsin-like receptor 0.0147 0.1775 0.174
Echinococcus granulosus tm gpcr rhodopsin 0.0147 0.1775 0.174
Brugia malayi follicle stimulating hormone receptor 0.0147 0.1775 0.1647
Echinococcus multilocularis rhodopsin orphan GPCR 0.0147 0.1775 0.174
Loa Loa (eye worm) hypothetical protein 0.0147 0.1775 0.1775
Brugia malayi putative neuropeptide receptor 0.0147 0.1775 0.1647
Echinococcus granulosus peptide allatostatin:somatostatin 0.0147 0.1775 0.174
Loa Loa (eye worm) hypothetical protein 0.0147 0.1775 0.1775
Echinococcus granulosus neuropeptides capa receptor 0.0147 0.1775 0.174
Schistosoma mansoni integrin beta subunit 0.0208 0.2668 0.2636
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0147 0.1775 0.174
Loa Loa (eye worm) hypothetical protein 0.0147 0.1775 0.1775
Loa Loa (eye worm) hypothetical protein 0.0147 0.1775 0.1775
Echinococcus granulosus rhodopsin orphan GPCR 0.0147 0.1775 0.174
Loa Loa (eye worm) cytochrome P450 family protein 0.0037 0.0154 0.0154
Mycobacterium tuberculosis Probable polypeptide deformylase Def (PDF) (formylmethionine deformylase) 0.0224 0.2893 0.5
Brugia malayi putative neuropeptide receptor NPR1 0.0147 0.1775 0.1647
Echinococcus granulosus fmrfamide receptor 0.0147 0.1775 0.174
Loa Loa (eye worm) hypothetical protein 0.0147 0.1775 0.1775
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0077 0.0751 0.5
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0147 0.1775 0.174
Loa Loa (eye worm) hypothetical protein 0.0147 0.1775 0.1775
Echinococcus granulosus alpha 1A adrenergic receptor 0.0147 0.1775 0.174
Loa Loa (eye worm) hypothetical protein 0.0147 0.1775 0.1775
Loa Loa (eye worm) hypothetical protein 0.0147 0.1775 0.1775
Loa Loa (eye worm) hypothetical protein 0.0147 0.1775 0.1775
Loa Loa (eye worm) hypothetical protein 0.0147 0.1775 0.1775
Schistosoma mansoni amine GPCR 0.0147 0.1775 0.174
Onchocerca volvulus Ceramide glucosyltransferase homolog 0.0709 1 1
Schistosoma mansoni neuropeptide receptor 0.0147 0.1775 0.174
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0147 0.1775 0.174
Loa Loa (eye worm) hypothetical protein 0.0147 0.1775 0.1775
Echinococcus granulosus hypothetical protein 0.0147 0.1775 0.174
Echinococcus multilocularis g protein coupled receptor 0.0147 0.1775 0.174
Trypanosoma cruzi polypeptide deformylase-like protein, putative 0.0085 0.0868 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0147 0.1775 0.174
Loa Loa (eye worm) hypothetical protein 0.0147 0.1775 0.1775
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0147 0.1775 0.174
Echinococcus granulosus orexin receptor type 2 0.0147 0.1775 0.174
Brugia malayi hypothetical protein 0.0147 0.1775 0.1647
Echinococcus granulosus g protein coupled receptor 0.0147 0.1775 0.174
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0147 0.1775 0.174
Brugia malayi Integrin beta pat-3 precursor 0.0362 0.4921 0.4841
Echinococcus granulosus 7tm_1 domain containing protein 0.0147 0.1775 0.174
Brugia malayi sulfakinin receptor protein 0.0147 0.1775 0.1647
Toxoplasma gondii hypothetical protein 0.0224 0.2893 0.5
Schistosoma mansoni amine GPCR 0.0147 0.1775 0.174
Echinococcus multilocularis rhodopsin orphan GPCR 0.0147 0.1775 0.174
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0147 0.1775 0.174
Echinococcus multilocularis rhodopsin orphan GPCR 0.0147 0.1775 0.174
Loa Loa (eye worm) hypothetical protein 0.0147 0.1775 0.1775
Trypanosoma brucei Peptide deformylase 2 0.0085 0.0868 1
Brugia malayi G-protein coupled receptor 0.0147 0.1775 0.1647
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0147 0.1775 0.174
Schistosoma mansoni biogenic amine (5HT) receptor 0.0147 0.1775 0.174
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0147 0.1775 0.174
Loa Loa (eye worm) hypothetical protein 0.0147 0.1775 0.1775
Loa Loa (eye worm) hypothetical protein 0.0147 0.1775 0.1775
Echinococcus multilocularis serotonin receptor 0.0147 0.1775 0.174
Brugia malayi Dopamine receptor 0.0147 0.1775 0.1647
Plasmodium vivax peptide deformylase, putative 0.0224 0.2893 0.5
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0147 0.1775 0.174
Echinococcus granulosus nmda type glutamate receptor 0.0032 0.0089 0.0046
Schistosoma mansoni opsin-like receptor 0.0147 0.1775 0.174
Echinococcus multilocularis neuropeptides capa receptor 0.0147 0.1775 0.174
Echinococcus multilocularis rhodopsin orphan GPCR 0.0147 0.1775 0.174
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0147 0.1775 0.174
Echinococcus multilocularis G-protein coupled receptor, putative 0.0147 0.1775 0.174
Echinococcus multilocularis dro:myosuppressin receptor 0.0147 0.1775 0.174
Echinococcus granulosus neuropeptide s receptor 0.0147 0.1775 0.174
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0147 0.1775 0.174
Loa Loa (eye worm) hypothetical protein 0.0147 0.1775 0.1775
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0147 0.1775 0.1647
Trypanosoma cruzi polypeptide deformylase-like protein, putative 0.0085 0.0868 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0147 0.1775 0.174
Echinococcus granulosus neuropeptide receptor 0.0147 0.1775 0.174
Schistosoma mansoni growth hormone secretagogue receptor 0.0147 0.1775 0.174
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0147 0.1775 0.174
Echinococcus granulosus neuropeptide FF receptor 2 0.0147 0.1775 0.174
Echinococcus granulosus rhodopsin orphan GPCR 0.0147 0.1775 0.174
Echinococcus multilocularis G protein coupled receptor 139 0.0147 0.1775 0.174
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0147 0.1775 0.174
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0147 0.1775 0.174
Brugia malayi Serotonin receptor 0.0147 0.1775 0.1647
Loa Loa (eye worm) hypothetical protein 0.0147 0.1775 0.1775
Echinococcus multilocularis g-protein coupled receptor 0.0147 0.1775 0.174
Brugia malayi neuropeptide F receptor 0.0147 0.1775 0.1647
Echinococcus multilocularis neuropeptide receptor A26 0.0147 0.1775 0.174
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0147 0.1775 0.174
Echinococcus multilocularis rhodopsin orphan GPCR 0.0147 0.1775 0.174
Brugia malayi ORL1-like opioid receptor 0.0147 0.1775 0.1647
Brugia malayi hypothetical protein 0.0147 0.1775 0.1647
Echinococcus granulosus g-protein coupled receptor 0.0147 0.1775 0.174
Echinococcus multilocularis neuropeptide receptor 0.0147 0.1775 0.174
Brugia malayi Kelch motif family protein 0.0057 0.0451 0.0302
Echinococcus granulosus rhodopsin orphan GPCR 0.0147 0.1775 0.174
Brugia malayi Dopamine receptor protein 1 0.0147 0.1775 0.1647
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0147 0.1775 0.174
Schistosoma mansoni biogenic amine receptor 0.0147 0.1775 0.174
Loa Loa (eye worm) hypothetical protein 0.0147 0.1775 0.1775
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0147 0.1775 0.174
Plasmodium falciparum peptide deformylase 0.0224 0.2893 0.5
Echinococcus granulosus integrin beta 2 0.0265 0.3501 0.3472
Schistosoma mansoni amine GPCR 0.0147 0.1775 0.174
Brugia malayi hypothetical protein 0.0147 0.1775 0.1647
Echinococcus multilocularis allatostatin A receptor 0.0147 0.1775 0.174
Echinococcus multilocularis fmrfamide receptor 0.0147 0.1775 0.174
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0147 0.1775 0.174
Wolbachia endosymbiont of Brugia malayi peptide deformylase 0.0224 0.2893 0.5
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0077 0.0751 0.5
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0147 0.1775 0.174
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0147 0.1775 0.174
Echinococcus multilocularis rhodopsin orphan GPCR 0.0147 0.1775 0.174
Brugia malayi Melatonin receptor type 1A 0.0147 0.1775 0.1647
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0147 0.1775 0.174
Loa Loa (eye worm) hypothetical protein 0.0147 0.1775 0.1775
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0147 0.1775 0.174
Brugia malayi G protein-coupled receptor F59B2.13 0.0147 0.1775 0.1647
Loa Loa (eye worm) kelch domain-containing protein family protein 0.0057 0.0451 0.0451
Echinococcus granulosus biogenic amine 5HT receptor 0.0147 0.1775 0.174
Loa Loa (eye worm) hypothetical protein 0.0057 0.0451 0.0451
Loa Loa (eye worm) hypothetical protein 0.0147 0.1775 0.1775
Brugia malayi hypothetical protein 0.0147 0.1775 0.1647
Loa Loa (eye worm) hypothetical protein 0.0147 0.1775 0.1775
Echinococcus granulosus g protein coupled receptor 0.0147 0.1775 0.174
Schistosoma mansoni hypothetical protein 0.0147 0.1775 0.174
Loa Loa (eye worm) hypothetical protein 0.0147 0.1775 0.1775
Echinococcus multilocularis nmda type glutamate receptor 0.0032 0.0089 0.0046
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0147 0.1775 0.174
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0147 0.1775 0.1647
Echinococcus granulosus rhodopsin orphan GPCR 0.0147 0.1775 0.174
Schistosoma mansoni hypothetical protein 0.0147 0.1775 0.174
Loa Loa (eye worm) TYRA-2 protein 0.0147 0.1775 0.1775
Schistosoma mansoni hypothetical protein 0.0147 0.1775 0.174
Echinococcus granulosus tm gpcr rhodopsin 0.0147 0.1775 0.174
Loa Loa (eye worm) hypothetical protein 0.0147 0.1775 0.1775
Loa Loa (eye worm) hypothetical protein 0.0147 0.1775 0.1775
Brugia malayi hypothetical protein 0.0147 0.1775 0.1647
Echinococcus granulosus neuropeptide receptor A26 0.0147 0.1775 0.174
Loa Loa (eye worm) hypothetical protein 0.0147 0.1775 0.1775
Echinococcus multilocularis neuropeptide s receptor 0.0147 0.1775 0.174
Loa Loa (eye worm) hypothetical protein 0.0147 0.1775 0.1775
Echinococcus granulosus neuropeptide Y receptor 0.0147 0.1775 0.174
Loa Loa (eye worm) G-protein coupled receptor 0.0147 0.1775 0.1775
Loa Loa (eye worm) hypothetical protein 0.0147 0.1775 0.1775
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0083 0.0831 0.0791
Echinococcus granulosus biogenic amine 5HT receptor 0.0147 0.1775 0.174
Schistosoma mansoni ceramide glucosyltransferase 0.0709 1 1
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0147 0.1775 0.174
Schistosoma mansoni amine GPCR 0.0147 0.1775 0.174
Loa Loa (eye worm) melatonin receptor type 1A 0.0147 0.1775 0.1775
Loa Loa (eye worm) hypothetical protein 0.0147 0.1775 0.1775
Loa Loa (eye worm) hypothetical protein 0.0147 0.1775 0.1775
Loa Loa (eye worm) cytochrome P450 family protein 0.0037 0.0154 0.0154
Echinococcus granulosus serotonin receptor 0.0147 0.1775 0.174
Echinococcus granulosus sex peptide receptor 0.0147 0.1775 0.174
Loa Loa (eye worm) hypothetical protein 0.0147 0.1775 0.1775
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0147 0.1775 0.1647
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0147 0.1775 0.174
Echinococcus multilocularis neuropeptide Y receptor 0.0147 0.1775 0.174
Echinococcus multilocularis serotonin receptor 0.0147 0.1775 0.174
Echinococcus granulosus rhodopsin orphan GPCR 0.0147 0.1775 0.174
Loa Loa (eye worm) hypothetical protein 0.0147 0.1775 0.1775
Brugia malayi larval opioid receptor 0.0147 0.1775 0.1647
Schistosoma mansoni hypothetical protein 0.0147 0.1775 0.174
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0147 0.1775 0.174
Echinococcus granulosus dro:myosuppressin receptor 0.0147 0.1775 0.174
Brugia malayi Serotonin receptor 0.0147 0.1775 0.1647
Schistosoma mansoni neuropeptide F-like receptor 0.0147 0.1775 0.174
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0083 0.0831 0.0831
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0147 0.1775 0.174
Echinococcus granulosus tm gpcr rhodopsin 0.0147 0.1775 0.174
Echinococcus multilocularis orexin receptor type 2 0.0147 0.1775 0.174
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0147 0.1775 0.174
Schistosoma mansoni neuropeptide receptor 0.0147 0.1775 0.174
Brugia malayi GnHR receptor homolog 0.0147 0.1775 0.1647
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0147 0.1775 0.1775
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0147 0.1775 0.174
Loa Loa (eye worm) hypothetical protein 0.0147 0.1775 0.1775
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0147 0.1775 0.174
Echinococcus granulosus rhodopsin orphan GPCR 0.0147 0.1775 0.174
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0147 0.1775 0.174
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0083 0.0831 0.0687
Brugia malayi RE15519p 0.0147 0.1775 0.1647
Schistosoma mansoni neuropeptide F-like receptor 0.0147 0.1775 0.174
Loa Loa (eye worm) hypothetical protein 0.0147 0.1775 0.1775
Echinococcus granulosus allatostatin A receptor 0.0147 0.1775 0.174
Brugia malayi AKH receptor 0.0147 0.1775 0.1647
Echinococcus multilocularis neuropeptides capa receptor 0.0147 0.1775 0.174
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0147 0.1775 0.1775
Loa Loa (eye worm) hypothetical protein 0.0147 0.1775 0.1775
Loa Loa (eye worm) hypothetical protein 0.0147 0.1775 0.1775
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0147 0.1775 0.174
Brugia malayi hypothetical protein 0.0147 0.1775 0.1647
Echinococcus granulosus rhodopsin orphan GPCR 0.0147 0.1775 0.174
Schistosoma mansoni voltage-gated potassium channel 0.009 0.0942 0.0903
Echinococcus granulosus neuropeptide Y receptor 0.0147 0.1775 0.174
Treponema pallidum polypeptide deformylase (def) 0.0224 0.2893 0.5
Brugia malayi Dopamine receptor protein 2 0.0147 0.1775 0.1647
Brugia malayi neuropeptide F receptor 0.0147 0.1775 0.1647
Echinococcus multilocularis neuropeptide Y receptor 0.0147 0.1775 0.174
Echinococcus granulosus somatostatin receptor 0.0147 0.1775 0.174
Mycobacterium ulcerans peptide deformylase 0.0224 0.2893 1
Echinococcus multilocularis neuropeptide FF receptor 2 0.0147 0.1775 0.174
Loa Loa (eye worm) hypothetical protein 0.0147 0.1775 0.1775
Loa Loa (eye worm) hypothetical protein 0.0147 0.1775 0.1775
Echinococcus granulosus G protein coupled receptor 139 0.0147 0.1775 0.174
Brugia malayi hypothetical protein 0.0147 0.1775 0.1647
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0147 0.1775 0.174
Brugia malayi G-protein coupled receptor 0.0147 0.1775 0.1647
Schistosoma mansoni biogenic amine (5HT) receptor 0.0147 0.1775 0.174
Brugia malayi G protein-coupled receptor 0.0147 0.1775 0.1647
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0147 0.1775 0.1775
Schistosoma mansoni myosin xvIII 0.0147 0.1775 0.174
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0147 0.1775 0.174
Echinococcus multilocularis neuropeptide receptor 0.0147 0.1775 0.174
Loa Loa (eye worm) neuropeptide F receptor 0.0147 0.1775 0.1775
Loa Loa (eye worm) neuropeptide F receptor 0.0147 0.1775 0.1775
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0147 0.1775 0.174
Schistosoma mansoni neuropeptide receptor 0.0147 0.1775 0.174
Trypanosoma brucei Polypeptide deformylase 1 0.0085 0.0868 1
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0147 0.1775 0.174
Echinococcus multilocularis integrin beta 2 0.0265 0.3501 0.3472
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0147 0.1775 0.1647
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0147 0.1775 0.1775
Loa Loa (eye worm) hypothetical protein 0.0147 0.1775 0.1775
Schistosoma mansoni amine GPCR 0.0147 0.1775 0.174
Brugia malayi hypothetical protein 0.0147 0.1775 0.1647
Chlamydia trachomatis peptide deformylase 0.0224 0.2893 0.5
Echinococcus multilocularis somatostatin receptor 0.0147 0.1775 0.174
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0147 0.1775 0.1647
Loa Loa (eye worm) CYP4Cod1 0.0037 0.0154 0.0154
Loa Loa (eye worm) hypothetical protein 0.0147 0.1775 0.1775

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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