Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | expressed protein | 0.0105 | 0.0608 | 0.0608 |
Schistosoma mansoni | protein tyrosine phosphatase non-receptor type nt1 | 0.0687 | 1 | 1 |
Chlamydia trachomatis | glycogen phosphorylase | 0.0319 | 0.4069 | 0.5 |
Giardia lamblia | Glycogen phosphorylase | 0.0319 | 0.4069 | 0.5 |
Entamoeba histolytica | glycogenphosphorylase, putative | 0.0138 | 0.1142 | 0.1639 |
Echinococcus granulosus | Glycosyl transferase family 35 | 0.0319 | 0.4069 | 0.4069 |
Loa Loa (eye worm) | protein-tyrosine phosphatase | 0.0687 | 1 | 1 |
Echinococcus multilocularis | glycogen phosphorylase | 0.0319 | 0.4069 | 0.4069 |
Loa Loa (eye worm) | Pin1-type peptidyl-prolyl cis-trans isomerase | 0.0105 | 0.0608 | 0.0608 |
Trichomonas vaginalis | rotamase, putative | 0.0105 | 0.0608 | 0.0114 |
Schistosoma mansoni | glycogen phosphorylase | 0.0138 | 0.1142 | 0.1142 |
Mycobacterium ulcerans | glycogen phosphorylase GlgP | 0.0138 | 0.1142 | 0.5 |
Trypanosoma cruzi | peptidyl-prolyl cis-trans isomerase | 0.0103 | 0.0568 | 0.5 |
Entamoeba histolytica | glycogen phosphorylase, putative | 0.0138 | 0.1142 | 0.1639 |
Schistosoma mansoni | hypothetical protein | 0.01 | 0.0526 | 0.0526 |
Toxoplasma gondii | peptidylprolyl isomerase | 0.0103 | 0.0568 | 0.5 |
Loa Loa (eye worm) | glycogen phosphorylase | 0.0319 | 0.4069 | 0.4069 |
Trichomonas vaginalis | glycogen phosphorylase, putative | 0.0319 | 0.4069 | 1 |
Schistosoma mansoni | glycogen phosphorylase | 0.0319 | 0.4069 | 0.4069 |
Echinococcus granulosus | tyrosine protein phosphatase non receptor type | 0.0687 | 1 | 1 |
Entamoeba histolytica | glycogen phosphorylase, putative | 0.0319 | 0.4069 | 1 |
Echinococcus multilocularis | tyrosine protein phosphatase non receptor type | 0.0687 | 1 | 1 |
Echinococcus granulosus | glycogen phosphorylase | 0.0319 | 0.4069 | 0.4069 |
Echinococcus multilocularis | Glycosyl transferase, family 35 | 0.0319 | 0.4069 | 0.4069 |
Mycobacterium tuberculosis | Probable glycogen phosphorylase GlgP | 0.0138 | 0.1142 | 0.5 |
Schistosoma mansoni | glycogen phosphorylase | 0.0319 | 0.4069 | 0.4069 |
Entamoeba histolytica | glycogen phosphorylase, putative | 0.0319 | 0.4069 | 1 |
Entamoeba histolytica | glycogen phosphorylase, putative | 0.0138 | 0.1142 | 0.1639 |
Brugia malayi | carbohydrate phosphorylase | 0.0319 | 0.4069 | 0.4069 |
Echinococcus multilocularis | glycogen phosphorylase | 0.0319 | 0.4069 | 0.4069 |
Echinococcus multilocularis | expressed protein | 0.0105 | 0.0608 | 0.0608 |
Echinococcus granulosus | glycogen phosphorylase | 0.0319 | 0.4069 | 0.4069 |
Trypanosoma cruzi | peptidyl-prolyl cis-trans isomerase | 0.0103 | 0.0568 | 0.5 |
Trypanosoma brucei | peptidyl-prolyl cis-trans isomerase/rotamase, putative | 0.0103 | 0.0568 | 1 |
Brugia malayi | Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 | 0.0105 | 0.0608 | 0.0608 |
Onchocerca volvulus | Glycogen phosphorylase homolog | 0.0319 | 0.4069 | 0.5 |
Leishmania major | peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative | 0.0103 | 0.0568 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0105 | 0.0608 | 0.0114 |
Trichomonas vaginalis | glycogen phosphorylase, putative | 0.0319 | 0.4069 | 1 |
Schistosoma mansoni | rotamase | 0.0105 | 0.0608 | 0.0608 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.