Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Treponema pallidum | polypeptide deformylase (def) | 0.0264 | 0.2884 | 0.5 |
Entamoeba histolytica | ribokinase, putative | 0.0032 | 0 | 0.5 |
Mycobacterium tuberculosis | Probable polypeptide deformylase Def (PDF) (formylmethionine deformylase) | 0.0264 | 0.2884 | 1 |
Echinococcus multilocularis | pseudouridine metabolizing bifunctional protein | 0.0032 | 0 | 0.5 |
Brugia malayi | Cytochrome P450 family protein | 0.0062 | 0.0379 | 0.0379 |
Entamoeba histolytica | fructokinase, putative | 0.0032 | 0 | 0.5 |
Schistosoma mansoni | ribokinase | 0.0032 | 0 | 0.5 |
Onchocerca volvulus | 0.0835 | 1 | 1 | |
Entamoeba histolytica | tagatose-6-phosphate kinase, putative | 0.0032 | 0 | 0.5 |
Mycobacterium ulcerans | peptide deformylase | 0.0264 | 0.2884 | 1 |
Echinococcus granulosus | pseudouridine metabolizing bifunctional protein | 0.0032 | 0 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0032 | 0 | 0.5 |
Entamoeba histolytica | Hypothetical protein T24C12.3, putative | 0.0032 | 0 | 0.5 |
Echinococcus multilocularis | ribokinase | 0.0032 | 0 | 0.5 |
Echinococcus multilocularis | adenosine kinase | 0.0032 | 0 | 0.5 |
Trichomonas vaginalis | ribokinase, putative | 0.0032 | 0 | 0.5 |
Toxoplasma gondii | hypothetical protein | 0.0264 | 0.2884 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0835 | 1 | 1 |
Chlamydia trachomatis | peptide deformylase | 0.0264 | 0.2884 | 0.5 |
Plasmodium falciparum | peptide deformylase | 0.0264 | 0.2884 | 0.5 |
Trypanosoma cruzi | Peptide deformylase 2, putative | 0.0101 | 0.0854 | 1 |
Mycobacterium leprae | PROBABLE POLYPEPTIDE DEFORMYLASE DEF (PDF) (FORMYLMETHIONINE DEFORMYLASE) | 0.0264 | 0.2884 | 1 |
Trypanosoma brucei | Polypeptide deformylase 1 | 0.0101 | 0.0854 | 1 |
Trypanosoma brucei | Peptide deformylase 2 | 0.0101 | 0.0854 | 1 |
Schistosoma mansoni | adenosine kinase | 0.0032 | 0 | 0.5 |
Leishmania major | polypeptide deformylase-like protein, putative | 0.0101 | 0.0854 | 1 |
Echinococcus granulosus | adenosine kinase | 0.0032 | 0 | 0.5 |
Trichomonas vaginalis | ribokinase, putative | 0.0032 | 0 | 0.5 |
Plasmodium vivax | peptide deformylase, putative | 0.0264 | 0.2884 | 0.5 |
Trypanosoma cruzi | polypeptide deformylase-like protein, putative | 0.0101 | 0.0854 | 1 |
Trichomonas vaginalis | ribokinase, putative | 0.0032 | 0 | 0.5 |
Echinococcus granulosus | ribokinase | 0.0032 | 0 | 0.5 |
Trypanosoma cruzi | Peptide deformylase 2, putative | 0.0101 | 0.0854 | 1 |
Entamoeba histolytica | kinase, PfkB family | 0.0032 | 0 | 0.5 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0062 | 0.0379 | 0.0379 |
Schistosoma mansoni | adenosine kinase | 0.0032 | 0 | 0.5 |
Giardia lamblia | Ribokinase | 0.0032 | 0 | 0.5 |
Wolbachia endosymbiont of Brugia malayi | peptide deformylase | 0.0264 | 0.2884 | 0.5 |
Trypanosoma cruzi | polypeptide deformylase-like protein, putative | 0.0101 | 0.0854 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.