Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | Clan SC, family S33, methylesterase-like serine peptidase | 0.0032 | 0.0132 | 0.5 |
Trypanosoma brucei | serine peptidase, Clan SC, Family S9B | 0.0136 | 0.2886 | 1 |
Trypanosoma cruzi | serine peptidase, Clan SC, Family S9B | 0.0136 | 0.2886 | 1 |
Brugia malayi | prolyl oligopeptidase family protein | 0.0032 | 0.0132 | 0.0132 |
Toxoplasma gondii | dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein | 0.0136 | 0.2886 | 1 |
Echinococcus multilocularis | dipeptidyl aminopeptidaseprotein | 0.0404 | 1 | 1 |
Mycobacterium tuberculosis | Probable protease II PtrBb [second part] (oligopeptidase B) | 0.0032 | 0.0132 | 0.5 |
Brugia malayi | prolyl oligopeptidase family protein | 0.0032 | 0.0132 | 0.0132 |
Entamoeba histolytica | prolyl oligopeptidase family protein | 0.0032 | 0.0132 | 0.5 |
Entamoeba histolytica | prolyl oligopeptidase family protein | 0.0032 | 0.0132 | 0.5 |
Plasmodium vivax | hypothetical protein, conserved | 0.0032 | 0.0132 | 0.5 |
Plasmodium falciparum | peptidase, putative | 0.0032 | 0.0132 | 0.5 |
Leishmania major | dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B | 0.0136 | 0.2886 | 1 |
Giardia lamblia | Alanyl dipeptidyl peptidase | 0.0032 | 0.0132 | 0.5 |
Trypanosoma brucei | Dipeptidyl-peptidase 8-like, putative | 0.0136 | 0.2886 | 1 |
Brugia malayi | prolyl oligopeptidase family protein | 0.0136 | 0.2886 | 0.2886 |
Mycobacterium tuberculosis | Probable peptidase | 0.0032 | 0.0132 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0104 | 0.2036 | 0.2036 |
Entamoeba histolytica | hypothetical protein, conserved | 0.0032 | 0.0132 | 0.5 |
Echinococcus multilocularis | Dipeptidyl peptidase 9 | 0.0136 | 0.2886 | 0.2791 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0032 | 0.0132 | 0.5 |
Onchocerca volvulus | Dipeptidyl peptidase family member 1 homolog | 0.0404 | 1 | 1 |
Trypanosoma cruzi | dipeptidyl-peptidase 8-like serine peptidase | 0.0136 | 0.2886 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0132 | 0.0132 |
Schistosoma mansoni | subfamily S9B unassigned peptidase (S09 family) | 0.0404 | 1 | 1 |
Loa Loa (eye worm) | prolyl oligopeptidase | 0.0032 | 0.0132 | 0.0132 |
Giardia lamblia | Alanyl dipeptidyl peptidase | 0.0032 | 0.0132 | 0.5 |
Brugia malayi | prolyl oligopeptidase family protein | 0.0032 | 0.0132 | 0.0132 |
Echinococcus granulosus | dipeptidyl aminopeptidaseprotein | 0.0404 | 1 | 1 |
Entamoeba histolytica | prolyl oligopeptidase family protein | 0.0032 | 0.0132 | 0.5 |
Echinococcus granulosus | Dipeptidyl peptidase 9 | 0.0136 | 0.2886 | 0.2791 |
Entamoeba histolytica | dipeptidyl-peptidase, putative | 0.0032 | 0.0132 | 0.5 |
Trichomonas vaginalis | Clan SC, family S9, acylaminoacyl-peptidase-like serine peptidase | 0.0032 | 0.0132 | 0.5 |
Loa Loa (eye worm) | prolyl oligopeptidase | 0.0404 | 1 | 1 |
Schistosoma mansoni | dipeptidyl-peptidase 9 (S09 family) | 0.0136 | 0.2886 | 0.2791 |
Entamoeba histolytica | dipeptidyl-peptidase, putative | 0.0032 | 0.0132 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0132 | 0.0132 |
Mycobacterium ulcerans | protease II (oligopeptidase B), PtrB | 0.0032 | 0.0132 | 0.5 |
Brugia malayi | hypothetical protein | 0.0104 | 0.2036 | 0.2036 |
Mycobacterium leprae | PROBABLE PROTEASE II PTRBB (OLIGOPEPTIDASE B) | 0.0032 | 0.0132 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0132 | 0.0132 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.