Detailed information for compound 888345

Basic information

Technical information
  • TDR Targets ID: 888345
  • Name: 1-(2-cyanoethyl)-3-(4-ethylphenyl)-1-(phenylm ethyl)urea
  • MW: 307.39 | Formula: C19H21N3O
  • H donors: 1 H acceptors: 2 LogP: 3.09 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 1
  • SMILES: N#CCCN(C(=O)Nc1ccc(cc1)CC)Cc1ccccc1
  • InChi: 1S/C19H21N3O/c1-2-16-9-11-18(12-10-16)21-19(23)22(14-6-13-20)15-17-7-4-3-5-8-17/h3-5,7-12H,2,6,14-15H2,1H3,(H,21,23)
  • InChiKey: DPLHWQWUUWMQHM-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 1-(benzyl)-1-(2-cyanoethyl)-3-(4-ethylphenyl)urea

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0046 0.9382 0.9382
Loa Loa (eye worm) hypothetical protein 0.0046 0.9382 1
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0041 0.8236 1
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0046 0.9382 1
Trypanosoma cruzi cytochrome P450, putative 0.0019 0.259 0.5
Schistosoma mansoni histamine h1 receptor 0.0046 0.9382 0.9382
Schistosoma mansoni neuropeptide F-like receptor 0.0046 0.9382 0.9382
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0046 0.9382 0.9382
Echinococcus granulosus rhodopsin orphan GPCR 0.0046 0.9382 1
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0046 0.9382 1
Brugia malayi sulfakinin receptor protein 0.0046 0.9382 1
Loa Loa (eye worm) hypothetical protein 0.0046 0.9382 1
Echinococcus granulosus tm gpcr rhodopsin 0.0046 0.9382 1
Onchocerca volvulus 0.0046 0.9382 0.5
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0046 0.9382 0.9382
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0046 0.9382 1
Echinococcus multilocularis g-protein coupled receptor 0.0046 0.9382 1
Loa Loa (eye worm) TYRA-2 protein 0.0046 0.9382 1
Brugia malayi ORL1-like opioid receptor 0.0046 0.9382 1
Brugia malayi hypothetical protein 0.0046 0.9382 1
Brugia malayi putative neuropeptide receptor 0.0046 0.9382 1
Schistosoma mansoni voltage-gated potassium channel 0.0013 0.1028 0.1028
Schistosoma mansoni alpha-1 adrenergic receptor 0.0046 0.9382 0.9382
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0046 0.9382 1
Loa Loa (eye worm) hypothetical protein 0.0046 0.9382 1
Echinococcus granulosus neuropeptide receptor A26 0.0046 0.9382 1
Brugia malayi G-protein coupled receptor 0.0046 0.9382 1
Brugia malayi AKH receptor 0.0046 0.9382 1
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0046 0.9382 1
Onchocerca volvulus 0.0046 0.9382 0.5
Loa Loa (eye worm) hypothetical protein 0.0046 0.9382 1
Loa Loa (eye worm) hypothetical protein 0.0046 0.9382 1
Brugia malayi Serotonin receptor 0.0046 0.9382 1
Onchocerca volvulus 0.0046 0.9382 0.5
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0046 0.9382 1
Brugia malayi Dopamine receptor protein 2 0.0046 0.9382 1
Brugia malayi hypothetical protein 0.0046 0.9382 1
Loa Loa (eye worm) hypothetical protein 0.0046 0.9382 1
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0044 0.8972 0.9563
Brugia malayi larval opioid receptor 0.0046 0.9382 1
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0046 0.9382 1
Echinococcus granulosus tm gpcr rhodopsin 0.0046 0.9382 1
Loa Loa (eye worm) hypothetical protein 0.0046 0.9382 1
Onchocerca volvulus 0.0046 0.9382 0.5
Schistosoma mansoni hypothetical protein 0.0046 0.9382 0.9382
Brugia malayi hypothetical protein 0.0046 0.9382 1
Echinococcus granulosus 7tm_1 domain containing protein 0.0046 0.9382 1
Schistosoma mansoni adenoreceptor 0.0046 0.9382 0.9382
Echinococcus granulosus sex peptide receptor 0.0046 0.9382 1
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0046 0.9382 1
Schistosoma mansoni growth hormone secretagogue receptor 0.0046 0.9382 0.9382
Schistosoma mansoni hypothetical protein 0.0046 0.9382 0.9382
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0044 0.8972 0.9563
Echinococcus granulosus voltage gated potassium channel 0.0013 0.1028 0.1095
Brugia malayi G-protein coupled receptor 0.0046 0.9382 1
Loa Loa (eye worm) hypothetical protein 0.0046 0.9382 1
Loa Loa (eye worm) hypothetical protein 0.0046 0.9382 1
Loa Loa (eye worm) hypothetical protein 0.0046 0.9382 1
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0013 0.1028 0.1095
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0046 0.9382 0.9382
Onchocerca volvulus 0.0046 0.9382 0.5
Echinococcus multilocularis neuropeptide Y receptor 0.0046 0.9382 1
Echinococcus multilocularis fmrfamide receptor 0.0046 0.9382 1
Loa Loa (eye worm) hypothetical protein 0.0013 0.1028 0.1095
Onchocerca volvulus Neuropeptide F receptor homolog 0.0046 0.9382 0.5
Loa Loa (eye worm) hypothetical protein 0.0046 0.9382 1
Loa Loa (eye worm) hypothetical protein 0.0046 0.9382 1
Loa Loa (eye worm) hypothetical protein 0.0046 0.9382 1
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0013 0.1028 0.1095
Schistosoma mansoni myosin xvIII 0.0046 0.9382 0.9382
Loa Loa (eye worm) hypothetical protein 0.0046 0.9382 1
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0046 0.9382 1
Echinococcus multilocularis G protein coupled receptor 139 0.0046 0.9382 1
Loa Loa (eye worm) hypothetical protein 0.0046 0.9382 1
Loa Loa (eye worm) hypothetical protein 0.0046 0.9382 1
Echinococcus granulosus alpha 1A adrenergic receptor 0.0046 0.9382 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0046 0.9382 1
Loa Loa (eye worm) hypothetical protein 0.0046 0.9382 1
Loa Loa (eye worm) neuropeptide F receptor 0.0046 0.9382 1
Brugia malayi Melatonin receptor type 1A 0.0046 0.9382 1
Brugia malayi Cytochrome P450 family protein 0.0019 0.259 0.2761
Brugia malayi Tachykinin-like peptides receptor 99D 0.0046 0.9382 1
Onchocerca volvulus 0.0046 0.9382 0.5
Loa Loa (eye worm) hypothetical protein 0.0046 0.9382 1
Loa Loa (eye worm) hypothetical protein 0.0046 0.9382 1
Echinococcus granulosus somatostatin receptor 0.0046 0.9382 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0046 0.9382 0.9382
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0046 0.9382 0.9382
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0046 0.9382 1
Echinococcus granulosus dro:myosuppressin receptor 0.0046 0.9382 1
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0044 0.8972 0.9563
Brugia malayi Dopamine receptor 0.0046 0.9382 1
Echinococcus granulosus biogenic amine 5HT receptor 0.0046 0.9382 1
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0046 0.9382 1
Brugia malayi hypothetical protein 0.0046 0.9382 1
Onchocerca volvulus 0.0046 0.9382 0.5
Loa Loa (eye worm) hypothetical protein 0.0046 0.9382 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0046 0.9382 1
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0019 0.259 0.5
Schistosoma mansoni biogenic amine receptor 0.0046 0.9382 0.9382
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0046 0.9382 0.9382
Echinococcus multilocularis rhodopsin orphan GPCR 0.0046 0.9382 1
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0046 0.9382 1
Echinococcus multilocularis orexin receptor type 2 0.0046 0.9382 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0046 0.9382 1
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0046 0.9382 0.9382
Loa Loa (eye worm) hypothetical protein 0.0046 0.9382 1
Echinococcus granulosus neuropeptide receptor 0.0046 0.9382 1
Echinococcus multilocularis serotonin receptor 0.0046 0.9382 1
Schistosoma mansoni biogenic amine receptor 0.0046 0.9382 0.9382
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0041 0.8236 1
Brugia malayi RE15519p 0.0046 0.9382 1
Echinococcus granulosus neuropeptide s receptor 0.0046 0.9382 1
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0046 0.9382 1
Echinococcus granulosus neuropeptides capa receptor 0.0046 0.9382 1
Loa Loa (eye worm) cytochrome P450 family protein 0.0019 0.259 0.2761
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0046 0.9382 1
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0046 0.9382 1
Onchocerca volvulus 0.0046 0.9382 0.5
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0046 0.9382 1
Loa Loa (eye worm) hypothetical protein 0.0046 0.9382 1
Brugia malayi hypothetical protein 0.0046 0.9382 1
Loa Loa (eye worm) hypothetical protein 0.0046 0.9382 1
Echinococcus multilocularis sex peptide receptor 0.0046 0.9382 1
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0046 0.9382 0.9382
Loa Loa (eye worm) hypothetical protein 0.0046 0.9382 1
Schistosoma mansoni opsin-like receptor 0.0046 0.9382 0.9382
Loa Loa (eye worm) hypothetical protein 0.0046 0.9382 1
Echinococcus multilocularis neuropeptide Y receptor 0.0046 0.9382 1
Schistosoma mansoni neuropeptide receptor 0.0046 0.9382 0.9382
Loa Loa (eye worm) hypothetical protein 0.0046 0.9382 1
Onchocerca volvulus 0.0046 0.9382 0.5
Echinococcus granulosus allatostatin A receptor 0.0046 0.9382 1
Loa Loa (eye worm) hypothetical protein 0.0046 0.9382 1
Onchocerca volvulus 0.0046 0.9382 0.5
Loa Loa (eye worm) hypothetical protein 0.001 0.0444 0.0473
Schistosoma mansoni opsin-like receptor 0.0046 0.9382 0.9382
Schistosoma mansoni biogenic amine (5HT) receptor 0.0046 0.9382 0.9382
Brugia malayi GnHR receptor homolog 0.0046 0.9382 1
Brugia malayi putative neuropeptide receptor NPR1 0.0046 0.9382 1
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0046 0.9382 1
Brugia malayi G protein-coupled receptor 0.0046 0.9382 1
Echinococcus granulosus neuropeptide Y receptor 0.0046 0.9382 1
Leishmania major cytochrome p450-like protein 0.0019 0.259 0.5
Echinococcus granulosus neuropeptide receptor 0.0046 0.9382 1
Schistosoma mansoni neuropeptide receptor 0.0046 0.9382 0.9382
Echinococcus granulosus 7TM GPCR rhodopsin 0.0046 0.9382 1
Echinococcus multilocularis G-protein coupled receptor, putative 0.0046 0.9382 1
Brugia malayi hypothetical protein 0.0046 0.9382 1
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0046 0.9382 0.9382
Loa Loa (eye worm) hypothetical protein 0.0046 0.9382 1
Loa Loa (eye worm) hypothetical protein 0.0046 0.9382 1
Loa Loa (eye worm) hypothetical protein 0.0046 0.9382 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0046 0.9382 1
Loa Loa (eye worm) hypothetical protein 0.0046 0.9382 1
Echinococcus granulosus neuropeptides capa receptor 0.0046 0.9382 1
Schistosoma mansoni amine GPCR 0.0046 0.9382 0.9382
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0046 0.9382 1
Schistosoma mansoni amine GPCR 0.0046 0.9382 0.9382
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0046 0.9382 0.9382
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0046 0.9382 1
Echinococcus granulosus neuropeptide FF receptor 2 0.0046 0.9382 1
Loa Loa (eye worm) hypothetical protein 0.0046 0.9382 1
Loa Loa (eye worm) neuropeptide F receptor 0.0046 0.9382 1
Schistosoma mansoni hypothetical protein 0.0046 0.9382 0.9382
Loa Loa (eye worm) hypothetical protein 0.0046 0.9382 1
Echinococcus multilocularis fmrfamide receptor 0.0046 0.9382 1
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0046 0.9382 1
Echinococcus granulosus hypothetical protein 0.0046 0.9382 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0046 0.9382 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0046 0.9382 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0046 0.9382 0.9382
Trypanosoma brucei cytochrome P450, putative 0.0019 0.259 0.5
Echinococcus granulosus g protein coupled receptor 0.0046 0.9382 1
Schistosoma mansoni voltage-gated potassium channel 0.0013 0.1028 0.1028
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0044 0.8972 0.9563
Schistosoma mansoni biogenic amine (5HT) receptor 0.0046 0.9382 0.9382
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0046 0.9382 0.9382
Loa Loa (eye worm) CYP4Cod1 0.0019 0.259 0.2761
Loa Loa (eye worm) hypothetical protein 0.0046 0.9382 1
Loa Loa (eye worm) hypothetical protein 0.0046 0.9382 1
Loa Loa (eye worm) hypothetical protein 0.0046 0.9382 1
Onchocerca volvulus 0.0046 0.9382 0.5
Echinococcus multilocularis neuropeptides capa receptor 0.0046 0.9382 1
Brugia malayi G protein-coupled receptor F59B2.13 0.0046 0.9382 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0046 0.9382 0.9382
Schistosoma mansoni voltage-gated potassium channel 0.0048 1 1
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0046 0.9382 1
Loa Loa (eye worm) hypothetical protein 0.0046 0.9382 1
Schistosoma mansoni amine GPCR 0.0046 0.9382 0.9382
Echinococcus multilocularis g protein coupled receptor 0.0046 0.9382 1
Loa Loa (eye worm) hypothetical protein 0.0046 0.9382 1
Schistosoma mansoni hypothetical protein 0.0046 0.9382 0.9382
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0046 0.9382 1
Onchocerca volvulus 0.0046 0.9382 0.5
Loa Loa (eye worm) G-protein coupled receptor 0.0046 0.9382 1
Onchocerca volvulus 0.0046 0.9382 0.5
Brugia malayi hypothetical protein 0.0046 0.9382 1
Schistosoma mansoni neuropeptide receptor 0.0046 0.9382 0.9382
Echinococcus multilocularis neuropeptide FF receptor 2 0.0046 0.9382 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0046 0.9382 1
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0046 0.9382 0.9382
Echinococcus granulosus tachykinin peptides receptor 99D 0.0046 0.9382 1
Schistosoma mansoni biogenic amine receptor 0.0046 0.9382 0.9382
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0046 0.9382 0.9382
Echinococcus granulosus fmrfamide receptor 0.0046 0.9382 1
Loa Loa (eye worm) G-protein coupled receptor 0.0046 0.9382 1
Echinococcus multilocularis g protein coupled receptor 0.0046 0.9382 1
Brugia malayi hypothetical protein 0.0046 0.9382 1
Loa Loa (eye worm) hypothetical protein 0.0046 0.9382 1
Loa Loa (eye worm) hypothetical protein 0.0046 0.9382 1
Echinococcus multilocularis neuropeptide s receptor 0.0046 0.9382 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0046 0.9382 1
Loa Loa (eye worm) hypothetical protein 0.0038 0.7495 0.7989
Onchocerca volvulus 0.0046 0.9382 0.5
Echinococcus multilocularis neuropeptide receptor 0.0046 0.9382 1
Echinococcus multilocularis neuropeptides capa receptor 0.0046 0.9382 1
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0046 0.9382 1
Echinococcus granulosus g protein coupled receptor 0.0046 0.9382 1
Schistosoma mansoni opsin-like receptor 0.0046 0.9382 0.9382
Brugia malayi hypothetical protein 0.0046 0.9382 1
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0046 0.9382 0.9382
Brugia malayi follicle stimulating hormone receptor 0.0046 0.9382 1
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0013 0.1028 0.1095
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0046 0.9382 0.9382
Echinococcus multilocularis rhodopsin orphan GPCR 0.0046 0.9382 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0046 0.9382 0.9382
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0046 0.9382 1
Echinococcus multilocularis voltage gated potassium channel 0.0013 0.1028 0.1095
Brugia malayi Dopamine receptor protein 1 0.0046 0.9382 1
Echinococcus granulosus orexin receptor type 2 0.0046 0.9382 1
Echinococcus granulosus g protein coupled receptor 0.0046 0.9382 1
Schistosoma mansoni amine GPCR 0.0046 0.9382 0.9382
Brugia malayi hypothetical protein 0.0046 0.9382 1
Echinococcus granulosus neuropeptide Y receptor 0.0046 0.9382 1
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0046 0.9382 1
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0046 0.9382 0.9382
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0046 0.9382 1
Loa Loa (eye worm) hypothetical protein 0.0046 0.9382 1
Trypanosoma cruzi cytochrome P450, putative 0.0019 0.259 0.5
Echinococcus granulosus tm gpcr rhodopsin 0.0046 0.9382 1
Onchocerca volvulus 0.0046 0.9382 0.5
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0046 0.9382 0.9382
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0046 0.9382 0.5
Onchocerca volvulus 0.0046 0.9382 0.5
Echinococcus multilocularis dro:myosuppressin receptor 0.0046 0.9382 1
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0046 0.9382 1
Loa Loa (eye worm) hypothetical protein 0.0046 0.9382 1
Schistosoma mansoni neuropeptide f receptor 76f 0.0046 0.9382 0.9382
Echinococcus granulosus rhodopsin orphan GPCR 0.0046 0.9382 1
Echinococcus multilocularis neuropeptide receptor A26 0.0046 0.9382 1
Schistosoma mansoni amine GPCR 0.0046 0.9382 0.9382
Echinococcus multilocularis g protein coupled receptor 0.0046 0.9382 1
Loa Loa (eye worm) hypothetical protein 0.0046 0.9382 1
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0046 0.9382 1
Loa Loa (eye worm) cytochrome P450 family protein 0.0019 0.259 0.2761
Brugia malayi neuropeptide F receptor 0.0046 0.9382 1
Loa Loa (eye worm) melatonin receptor type 1A 0.0046 0.9382 1
Echinococcus granulosus serotonin receptor 0.0046 0.9382 1
Loa Loa (eye worm) hypothetical protein 0.0046 0.9382 1
Onchocerca volvulus 0.0046 0.9382 0.5
Echinococcus multilocularis neuropeptide receptor 0.0046 0.9382 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0046 0.9382 1
Echinococcus granulosus g-protein coupled receptor 0.0046 0.9382 1
Echinococcus multilocularis allatostatin A receptor 0.0046 0.9382 1
Echinococcus multilocularis serotonin receptor 0.0046 0.9382 1
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0046 0.9382 0.9382
Brugia malayi neuropeptide F receptor 0.0046 0.9382 1
Schistosoma mansoni neuropeptide F-like receptor 0.0046 0.9382 0.9382
Echinococcus multilocularis somatostatin receptor 0.0046 0.9382 1
Echinococcus granulosus G protein coupled receptor 139 0.0046 0.9382 1
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0046 0.9382 1
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0046 0.9382 1
Schistosoma mansoni neuropeptide receptor 0.0046 0.9382 0.9382
Echinococcus granulosus biogenic amine 5HT receptor 0.0046 0.9382 1
Echinococcus granulosus peptide allatostatin:somatostatin 0.0046 0.9382 1
Loa Loa (eye worm) hypothetical protein 0.0046 0.9382 1
Brugia malayi Cytochrome P450 family protein 0.0019 0.259 0.2761
Brugia malayi Serotonin receptor 0.0046 0.9382 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0046 0.9382 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0046 0.9382 1

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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