Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | hypothetical protein | 0.0291 | 0.3836 | 0.3879 |
Brugia malayi | Transient-receptor-potential like protein | 0.0045 | 0.0006 | 0.001 |
Echinococcus granulosus | short transient receptor potential channel 6 | 0.0073 | 0.0438 | 0.0438 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0209 | 0.2553 | 0.5 |
Echinococcus multilocularis | hyperpolarization activated cyclic | 0.05 | 0.7092 | 0.717 |
Schistosoma mansoni | transient receptor potential channel | 0.0073 | 0.0438 | 0.0617 |
Echinococcus multilocularis | transient receptor potential gamma protein | 0.0106 | 0.0942 | 0.0952 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0006 | 0.0067 |
Schistosoma mansoni | transient receptor potential channel 4 | 0.0106 | 0.0942 | 0.1328 |
Echinococcus multilocularis | short transient receptor potential channel 6 | 0.0073 | 0.0438 | 0.0442 |
Brugia malayi | Serotonin receptor | 0.046 | 0.6469 | 1 |
Echinococcus multilocularis | TRP (transient receptor potential) channel | 0.0045 | 0.0006 | 0.0006 |
Echinococcus granulosus | transient receptor potential gamma protein | 0.0106 | 0.0942 | 0.0942 |
Echinococcus granulosus | transient receptor potential ion channel A | 0.0092 | 0.0738 | 0.0738 |
Echinococcus multilocularis | transient receptor potential ion channel A | 0.0092 | 0.0738 | 0.0746 |
Echinococcus granulosus | short transient receptor potential channel 6 | 0.0073 | 0.0438 | 0.0438 |
Echinococcus multilocularis | short transient receptor potential channel 6 | 0.0073 | 0.0438 | 0.0442 |
Echinococcus multilocularis | hyperpolarization activated cyclic | 0.05 | 0.7092 | 0.717 |
Echinococcus multilocularis | conserved hypothetical protein | 0.068 | 0.9891 | 1 |
Echinococcus granulosus | TRP transient receptor potential channel | 0.0045 | 0.0006 | 0.0006 |
Schistosoma mansoni | transient receptor potential channel | 0.0106 | 0.0942 | 0.1328 |
Schistosoma mansoni | transient receptor potential channel | 0.0073 | 0.0438 | 0.0617 |
Schistosoma mansoni | hypothetical protein | 0.0291 | 0.3836 | 0.5409 |
Echinococcus multilocularis | potassium:sodium hyperpolarization activated | 0.05 | 0.7092 | 0.717 |
Loa Loa (eye worm) | hypothetical protein | 0.006 | 0.0234 | 0.248 |
Loa Loa (eye worm) | hypothetical protein | 0.0106 | 0.0942 | 1 |
Schistosoma mansoni | hyperpolarization activated cyclic nucleotide-gated potassium channel | 0.0196 | 0.2349 | 0.3313 |
Echinococcus granulosus | hyperpolarization activated cyclic | 0.05 | 0.7092 | 0.7092 |
Echinococcus granulosus | Ion_trans_N domain containing protein | 0.0291 | 0.3836 | 0.3836 |
Echinococcus granulosus | potassium:sodium hyperpolarization activated | 0.05 | 0.7092 | 0.7092 |
Echinococcus granulosus | hyperpolarization activated cyclic | 0.05 | 0.7092 | 0.7092 |
Schistosoma mansoni | hyperpolarization activated cyclic nucleotide-gated potassium channel | 0.05 | 0.7092 | 1 |
Schistosoma mansoni | hyperpolarization activated cyclic nucleotide-gated potassium channel | 0.05 | 0.7092 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.