Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0263 | 0.0637 | 0.0637 |
Toxoplasma gondii | acylaminoacyl-peptidase, putative | 0.0263 | 0.0637 | 0.1374 |
Echinococcus granulosus | acylamino acid releasing enzyme | 0.0263 | 0.0637 | 0.0608 |
Schistosoma mansoni | subfamily S9B unassigned peptidase (S09 family) | 0.3185 | 1 | 1 |
Echinococcus granulosus | dipeptidyl aminopeptidaseprotein | 0.3185 | 1 | 1 |
Brugia malayi | prolyl oligopeptidase family protein | 0.1178 | 0.357 | 0.355 |
Entamoeba histolytica | dipeptidyl-peptidase, putative | 0.0263 | 0.0637 | 1 |
Trichomonas vaginalis | Clan SC, family S28, unassigned serine peptidase | 0.0127 | 0.0202 | 0.3006 |
Entamoeba histolytica | dipeptidyl-peptidase, putative | 0.0263 | 0.0637 | 1 |
Trypanosoma cruzi | prolyl endopeptidase | 0.0263 | 0.0637 | 0.1291 |
Trichomonas vaginalis | lysosomal pro-X carboxypeptidase, putative | 0.0127 | 0.0202 | 0.3006 |
Trichomonas vaginalis | Clan SC, family S28, unassigned serine peptidase | 0.0127 | 0.0202 | 0.3006 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0127 | 0.0202 | 0.3006 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0263 | 0.0637 | 0.1291 |
Entamoeba histolytica | prolyl oligopeptidase family protein | 0.0263 | 0.0637 | 1 |
Trypanosoma cruzi | oligopeptidase B-like protein, putative | 0.0263 | 0.0637 | 0.1291 |
Leishmania major | dipeptidyl-peptidase 8-like serine peptidase, putative,serine peptidase, Clan SC, Family S9B | 0.1178 | 0.357 | 1 |
Loa Loa (eye worm) | prolyl oligopeptidase | 0.3185 | 1 | 1 |
Trichomonas vaginalis | Clan SC, family S33, methylesterase-like serine peptidase | 0.0263 | 0.0637 | 1 |
Trichomonas vaginalis | Clan SC, family S9, acylaminoacyl-peptidase-like serine peptidase | 0.0263 | 0.0637 | 1 |
Echinococcus multilocularis | Lysosomal Pro X carboxypeptidase | 0.0127 | 0.0202 | 0.0172 |
Loa Loa (eye worm) | prolyl oligopeptidase | 0.0263 | 0.0637 | 0.0637 |
Trichomonas vaginalis | Clan SC, family S28, unassigned serine peptidase | 0.0127 | 0.0202 | 0.3006 |
Echinococcus granulosus | Dipeptidyl peptidase 9 | 0.1178 | 0.357 | 0.355 |
Schistosoma mansoni | prolyl oligopeptidase (S09 family) | 0.0263 | 0.0637 | 0.0587 |
Echinococcus multilocularis | acylamino acid releasing enzyme | 0.0263 | 0.0637 | 0.0608 |
Brugia malayi | Serine protease Z688.6 precursor | 0.0127 | 0.0202 | 0.0172 |
Toxoplasma gondii | dipeptidyl peptidase iv (dpp iv) n-terminal region domain-containing protein | 0.1115 | 0.3367 | 1 |
Trichomonas vaginalis | Clan SC, family S28, unassigned serine peptidase | 0.0127 | 0.0202 | 0.3006 |
Entamoeba histolytica | prolyl oligopeptidase family protein | 0.0263 | 0.0637 | 1 |
Echinococcus granulosus | Lysosomal Pro X carboxypeptidase | 0.2366 | 0.7376 | 0.7368 |
Loa Loa (eye worm) | voltage and ligand gated potassium channel | 0.0074 | 0.0031 | 0.0031 |
Brugia malayi | prolyl oligopeptidase family protein | 0.0263 | 0.0637 | 0.0608 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0263 | 0.0637 | 0.1291 |
Echinococcus granulosus | Lysosomal Pro X carboxypeptidase | 0.0127 | 0.0202 | 0.0172 |
Loa Loa (eye worm) | hypothetical protein | 0.0127 | 0.0202 | 0.0202 |
Loa Loa (eye worm) | hypothetical protein | 0.0127 | 0.0202 | 0.0202 |
Toxoplasma gondii | prolyl endopeptidase | 0.0263 | 0.0637 | 0.1374 |
Trypanosoma cruzi | oligopeptidase b | 0.0263 | 0.0637 | 0.1291 |
Trypanosoma cruzi | serine peptidase, Clan SC, Family S9B | 0.1178 | 0.357 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0852 | 0.2525 | 0.2525 |
Loa Loa (eye worm) | hypothetical protein | 0.0263 | 0.0637 | 0.0637 |
Entamoeba histolytica | hypothetical protein, conserved | 0.0263 | 0.0637 | 1 |
Onchocerca volvulus | Dipeptidyl peptidase family member 1 homolog | 0.3185 | 1 | 1 |
Trypanosoma cruzi | oligopeptidase b | 0.0263 | 0.0637 | 0.1291 |
Trichomonas vaginalis | Clan SC, family S28, unassigned serine peptidase | 0.0127 | 0.0202 | 0.3006 |
Echinococcus multilocularis | Dipeptidyl peptidase 9 | 0.1178 | 0.357 | 0.355 |
Trichomonas vaginalis | Clan SC, family S28, unassigned serine peptidase | 0.0127 | 0.0202 | 0.3006 |
Mycobacterium tuberculosis | Probable peptidase | 0.0263 | 0.0637 | 0.5 |
Trypanosoma cruzi | serine peptidase, clan SC, family S9A-like protein, putative | 0.0263 | 0.0637 | 0.1291 |
Trypanosoma brucei | serine peptidase, Clan SC, Family S9B | 0.1178 | 0.357 | 1 |
Plasmodium falciparum | peptidase, putative | 0.0263 | 0.0637 | 0.5 |
Giardia lamblia | Alanyl dipeptidyl peptidase | 0.0263 | 0.0637 | 1 |
Trichomonas vaginalis | Clan SC, family S28, unassigned serine peptidase | 0.0127 | 0.0202 | 0.3006 |
Loa Loa (eye worm) | hypothetical protein | 0.0326 | 0.084 | 0.084 |
Trichomonas vaginalis | prolylcarboxypeptidase, putative | 0.0127 | 0.0202 | 0.3006 |
Brugia malayi | hypothetical protein | 0.0852 | 0.2525 | 0.2502 |
Trichomonas vaginalis | Clan SC, family S28, unassigned serine peptidase | 0.0127 | 0.0202 | 0.3006 |
Plasmodium vivax | hypothetical protein, conserved | 0.0263 | 0.0637 | 0.5 |
Echinococcus granulosus | prolyl endopeptidase | 0.0263 | 0.0637 | 0.0608 |
Trypanosoma cruzi | dipeptidyl-peptidase 8-like serine peptidase | 0.1178 | 0.357 | 1 |
Schistosoma mansoni | acylaminoacyl-peptidase (S09 family) | 0.0263 | 0.0637 | 0.0587 |
Loa Loa (eye worm) | hypothetical protein | 0.0127 | 0.0202 | 0.0202 |
Brugia malayi | prolyl oligopeptidase family protein | 0.0263 | 0.0637 | 0.0608 |
Trichomonas vaginalis | prolylcarboxypeptidase, putative | 0.0127 | 0.0202 | 0.3006 |
Schistosoma mansoni | family S28 unassigned peptidase (S28 family) | 0.2366 | 0.7376 | 0.7362 |
Mycobacterium ulcerans | protease II (oligopeptidase B), PtrB | 0.0263 | 0.0637 | 0.5 |
Trichomonas vaginalis | Clan SC, family S28, unassigned serine peptidase | 0.0127 | 0.0202 | 0.3006 |
Schistosoma mansoni | lysosomal Pro-Xaa carboxypeptidase (S28 family) | 0.0127 | 0.0202 | 0.015 |
Echinococcus multilocularis | prolyl endopeptidase | 0.0263 | 0.0637 | 0.0608 |
Schistosoma mansoni | prolyl oligopeptidase (S09 family) | 0.0263 | 0.0637 | 0.0587 |
Toxoplasma gondii | hypothetical protein | 0.0263 | 0.0637 | 0.1374 |
Echinococcus multilocularis | Lysosomal Pro X carboxypeptidase | 0.2366 | 0.7376 | 0.7368 |
Mycobacterium leprae | PROBABLE PROTEASE II PTRBB (OLIGOPEPTIDASE B) | 0.0263 | 0.0637 | 0.5 |
Echinococcus multilocularis | dipeptidyl aminopeptidaseprotein | 0.3185 | 1 | 1 |
Schistosoma mansoni | prolyl oligopeptidase (S09 family) | 0.0263 | 0.0637 | 0.0587 |
Trichomonas vaginalis | Clan SC, family S28, unassigned serine peptidase | 0.0127 | 0.0202 | 0.3006 |
Loa Loa (eye worm) | hypothetical protein | 0.0127 | 0.0202 | 0.0202 |
Brugia malayi | Serine protease Z688.6 precursor | 0.0127 | 0.0202 | 0.0172 |
Schistosoma mansoni | dipeptidyl-peptidase 9 (S09 family) | 0.1178 | 0.357 | 0.3536 |
Trichomonas vaginalis | Clan SC, family S28, unassigned serine peptidase | 0.0127 | 0.0202 | 0.3006 |
Brugia malayi | Serine carboxypeptidase S28 family protein | 0.0127 | 0.0202 | 0.0172 |
Onchocerca volvulus | Prolyl endopeptidase homolog | 0.0263 | 0.0637 | 0.0444 |
Brugia malayi | prolyl oligopeptidase family protein | 0.0263 | 0.0637 | 0.0608 |
Trichomonas vaginalis | Clan SC, family S28, unassigned serine peptidase | 0.0127 | 0.0202 | 0.3006 |
Trypanosoma brucei | Dipeptidyl-peptidase 8-like, putative | 0.1178 | 0.357 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0263 | 0.0637 | 1 |
Entamoeba histolytica | prolyl oligopeptidase family protein | 0.0263 | 0.0637 | 1 |
Giardia lamblia | Alanyl dipeptidyl peptidase | 0.0263 | 0.0637 | 1 |
Mycobacterium tuberculosis | Probable protease II PtrBb [second part] (oligopeptidase B) | 0.0263 | 0.0637 | 0.5 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0127 | 0.0202 | 0.3006 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.