Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Leishmania major | hypothetical protein, conserved | 0.0025 | 0.0951 | 0.5 |
Echinococcus granulosus | Ataxin 2 N terminaldomain containing protein | 0.0011 | 0.0141 | 0.0444 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0016 | 0.041 | 0.1292 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0051 | 0.2414 | 0.2414 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.2414 | 0.2414 |
Schistosoma mansoni | tar DNA-binding protein | 0.0064 | 0.3173 | 1 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0016 | 0.041 | 0.1292 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.1486 | 0.1486 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0016 | 0.041 | 0.1292 |
Schistosoma mansoni | tar DNA-binding protein | 0.0064 | 0.3173 | 1 |
Brugia malayi | MH2 domain containing protein | 0.012 | 0.6438 | 0.6438 |
Schistosoma mansoni | tar DNA-binding protein | 0.0064 | 0.3173 | 1 |
Brugia malayi | hypothetical protein | 0.0016 | 0.043 | 0.043 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0025 | 0.0951 | 0.5 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0025 | 0.0951 | 0.5 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.012 | 0.6438 | 0.6438 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.041 | 0.1292 |
Echinococcus multilocularis | GPCR, family 2 | 0.0016 | 0.041 | 0.1292 |
Echinococcus granulosus | tar DNA binding protein | 0.0064 | 0.3173 | 1 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0051 | 0.2414 | 0.2414 |
Echinococcus multilocularis | tar DNA binding protein | 0.0064 | 0.3173 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0182 | 1 | 1 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.012 | 0.6438 | 0.6438 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0035 | 0.1486 | 0.1486 |
Schistosoma mansoni | hypothetical protein | 0.0035 | 0.1486 | 0.4684 |
Brugia malayi | hypothetical protein | 0.0025 | 0.0951 | 0.0951 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.041 | 0.041 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0025 | 0.0951 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.041 | 0.1292 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0016 | 0.041 | 0.041 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0064 | 0.3173 | 0.3173 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0016 | 0.041 | 0.041 |
Echinococcus granulosus | GPCR family 2 | 0.0016 | 0.041 | 0.1292 |
Schistosoma mansoni | tar DNA-binding protein | 0.0064 | 0.3173 | 1 |
Loa Loa (eye worm) | TAR-binding protein | 0.0064 | 0.3173 | 0.3173 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0951 | 0.0951 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0016 | 0.041 | 0.041 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.041 | 0.1292 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0025 | 0.0951 | 0.5 |
Brugia malayi | RNA binding protein | 0.0064 | 0.3173 | 0.3173 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.041 | 0.1292 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0025 | 0.0951 | 0.5 |
Echinococcus multilocularis | Ataxin 2, N terminal,domain containing protein | 0.0011 | 0.0141 | 0.0444 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0051 | 0.2414 | 0.2414 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0025 | 0.0951 | 1 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0016 | 0.041 | 0.1292 |
Brugia malayi | TAR-binding protein | 0.0064 | 0.3173 | 0.3173 |
Onchocerca volvulus | Rap guanine nucleotide exchange factor 1 homolog | 0.0182 | 1 | 1 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0064 | 0.3173 | 0.3173 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0025 | 0.0951 | 0.5 |
Schistosoma mansoni | tar DNA-binding protein | 0.0064 | 0.3173 | 1 |
Loa Loa (eye worm) | RNA binding protein | 0.0064 | 0.3173 | 0.3173 |
Schistosoma mansoni | hypothetical protein | 0.0011 | 0.0141 | 0.0444 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.