Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | CMGC family protein kinase | 0.0505 | 0 | 0.5 |
Trypanosoma brucei | CMGC/DYRK protein kinase, putative | 0.0877 | 0.1877 | 1 |
Leishmania major | serine/threonine-protein kinase, putative,protein kinase, putative | 0.0877 | 0.1877 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0864 | 0.1809 | 0.1809 |
Loa Loa (eye worm) | hypothetical protein | 0.0864 | 0.1809 | 0.1809 |
Loa Loa (eye worm) | CMGC/DYRK/DYRK1 protein kinase | 0.0877 | 0.1877 | 0.1877 |
Toxoplasma gondii | CMGC kinase, MAPK family (ERK) MAPK-1 | 0.0505 | 0 | 0.5 |
Echinococcus multilocularis | dual specificity | 0.0877 | 0.1877 | 0.1877 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0505 | 0 | 0.5 |
Trypanosoma cruzi | CMGC/DYRK protein kinase, putative | 0.0877 | 0.1877 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1192 | 0.3462 | 0.3462 |
Loa Loa (eye worm) | hypothetical protein | 0.2489 | 1 | 1 |
Giardia lamblia | Kinase, CMGC MAPK | 0.0505 | 0 | 0.5 |
Echinococcus multilocularis | cyclin dependent kinase 5 activator 1 | 0.2489 | 1 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0505 | 0 | 0.5 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0877 | 0.1877 | 0.1877 |
Entamoeba histolytica | protein kinase domain containing protein | 0.0877 | 0.1877 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.1192 | 0.3462 | 0.3462 |
Entamoeba histolytica | protein kinase, putative | 0.0877 | 0.1877 | 0.5 |
Schistosoma mansoni | cyclin-dependent kinase 5 activator | 0.2489 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.1192 | 0.3462 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0505 | 0 | 0.5 |
Brugia malayi | Protein kinase domain containing protein | 0.0877 | 0.1877 | 0.5421 |
Trypanosoma cruzi | CMGC/DYRK protein kinase, putative | 0.0877 | 0.1877 | 1 |
Echinococcus granulosus | dual specificity | 0.0877 | 0.1877 | 0.1877 |
Entamoeba histolytica | hypothetical protein | 0.0877 | 0.1877 | 0.5 |
Entamoeba histolytica | protein kinase, putative | 0.0877 | 0.1877 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.