Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.0231 | 1 | 1 |
Echinococcus multilocularis | geminin | 0.0165 | 0.6506 | 0.6295 |
Plasmodium falciparum | carbonic anhydrase | 0.0054 | 0.057 | 0.5 |
Brugia malayi | Putative carbonic anhydrase 5 precursor | 0.0054 | 0.057 | 0.039 |
Echinococcus multilocularis | poly (adp ribose) polymerase 2 | 0.0077 | 0.1789 | 0.1293 |
Trypanosoma cruzi | poly(ADP-ribose) polymerase, putative | 0.0077 | 0.1789 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0107 | 0.3376 | 0.2975 |
Leishmania major | carbonic anhydrase-like protein | 0.0054 | 0.057 | 0.5 |
Schistosoma mansoni | poly [ADP-ribose] polymerase | 0.014 | 0.5165 | 0.7877 |
Schistosoma mansoni | carbonic anhydrase | 0.0054 | 0.057 | 0.0606 |
Echinococcus multilocularis | poly (ADP ribose) polymerase 1 | 0.014 | 0.5165 | 0.4873 |
Schistosoma mansoni | carbonic anhydrase II (carbonate dehydratase II) | 0.0054 | 0.057 | 0.0606 |
Echinococcus granulosus | geminin | 0.0165 | 0.6506 | 0.6506 |
Echinococcus granulosus | carbonic anhydrase | 0.0054 | 0.057 | 0.057 |
Schistosoma mansoni | carbonic anhydrase-related | 0.0054 | 0.057 | 0.0606 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.0054 | 0.057 | 0.039 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.0054 | 0.057 | 0.039 |
Schistosoma mansoni | poly [ADP-ribose] polymerase | 0.0067 | 0.1233 | 0.1656 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0231 | 1 | 1 |
Echinococcus granulosus | carbonic anhydrase II | 0.0054 | 0.057 | 0.057 |
Echinococcus granulosus | carbonic anhydrase | 0.0054 | 0.057 | 0.057 |
Entamoeba histolytica | poly(ADP-ribose) polymerase, putative | 0.014 | 0.5165 | 0.5 |
Schistosoma mansoni | poly [ADP-ribose] polymerase | 0.0077 | 0.1789 | 0.2535 |
Brugia malayi | WGR domain containing protein | 0.014 | 0.5165 | 0.5073 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0231 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0165 | 0.6506 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0054 | 0.057 | 0.0606 |
Brugia malayi | Carbonic anhydrase like protein 2 precursor | 0.0054 | 0.057 | 0.039 |
Trypanosoma brucei | poly(adp-ribose) polymerase | 0.0077 | 0.1789 | 1 |
Schistosoma mansoni | carbonic anhydrase-related | 0.0054 | 0.057 | 0.0606 |
Echinococcus granulosus | poly ADP ribose polymerase 1 | 0.014 | 0.5165 | 0.5165 |
Onchocerca volvulus | 0.0047 | 0.0187 | 0.5 | |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.0054 | 0.057 | 0.039 |
Trypanosoma cruzi | poly(ADP-ribose) polymerase, putative | 0.0077 | 0.1789 | 1 |
Loa Loa (eye worm) | poly(ADP-ribose) polymerase | 0.0055 | 0.0625 | 0.0059 |
Schistosoma mansoni | carbonic anhydrase-related | 0.0054 | 0.057 | 0.0606 |
Echinococcus granulosus | poly adp ribose polymerase 2 | 0.0077 | 0.1789 | 0.1789 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.1789 | 0.1293 |
Brugia malayi | Carbonic anhydrase like protein 2 precursor | 0.0054 | 0.057 | 0.039 |
Toxoplasma gondii | poly(ADP-ribose) polymerase catalytic domain-containing protein | 0.0146 | 0.5458 | 1 |
Schistosoma mansoni | carbonic anhydrase II (carbonate dehydratase II) | 0.0054 | 0.057 | 0.0606 |
Echinococcus granulosus | carbonic anhydrase | 0.0054 | 0.057 | 0.057 |
Brugia malayi | WGR domain containing protein | 0.0077 | 0.1789 | 0.1632 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.0054 | 0.057 | 0.039 |
Schistosoma mansoni | hypothetical protein | 0.0165 | 0.6506 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.