Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | CMGC family protein kinase | 0.0088 | 0.0413 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0122 | 0.1182 | 0.1182 |
Trypanosoma brucei | CMGC/DYRK protein kinase, putative | 0.0181 | 0.2494 | 1 |
Plasmodium vivax | protein kinase Crk2 | 0.0088 | 0.0413 | 0.5 |
Brugia malayi | hypothetical protein | 0.0247 | 0.3976 | 1 |
Trypanosoma cruzi | CMGC/DYRK protein kinase, putative | 0.0181 | 0.2494 | 1 |
Brugia malayi | Protein kinase domain containing protein | 0.0181 | 0.2494 | 0.6274 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0088 | 0.0413 | 0.0413 |
Onchocerca volvulus | Huntingtin homolog | 0.0122 | 0.1182 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0179 | 0.2453 | 0.2453 |
Loa Loa (eye worm) | hypothetical protein | 0.0179 | 0.2453 | 0.2453 |
Loa Loa (eye worm) | CMGC/CDK/CDC2 protein kinase | 0.0088 | 0.0413 | 0.0413 |
Echinococcus multilocularis | dual specificity | 0.0181 | 0.2494 | 0.2171 |
Giardia lamblia | Kinase, CMGC CDK | 0.0088 | 0.0413 | 0.5 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0181 | 0.2494 | 0.2494 |
Brugia malayi | cell division control protein 2 homolog | 0.0088 | 0.0413 | 0.1038 |
Giardia lamblia | Kinase, CMGC CDK | 0.0088 | 0.0413 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.0371 | 0.0371 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0102 | 0.072 | 0.072 |
Brugia malayi | hypothetical protein | 0.0122 | 0.1182 | 0.2973 |
Echinococcus multilocularis | cyclin dependent kinase 5 activator 1 | 0.0516 | 1 | 1 |
Onchocerca volvulus | Huntingtin homolog | 0.0122 | 0.1182 | 0.5 |
Schistosoma mansoni | cyclin-dependent kinase 5 activator | 0.0516 | 1 | 1 |
Entamoeba histolytica | protein kinase domain containing protein | 0.0181 | 0.2494 | 1 |
Echinococcus granulosus | dual specificity | 0.0181 | 0.2494 | 0.2171 |
Leishmania major | serine/threonine-protein kinase, putative,protein kinase, putative | 0.0181 | 0.2494 | 1 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0088 | 0.0413 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0247 | 0.3976 | 0.3976 |
Brugia malayi | Protein kinase domain containing protein | 0.0088 | 0.0413 | 0.1038 |
Loa Loa (eye worm) | CMGC/CDK/CDK5 protein kinase | 0.0088 | 0.0413 | 0.0413 |
Toxoplasma gondii | cell-cycle-associated protein kinase CDK, putative | 0.0088 | 0.0413 | 0.5 |
Trypanosoma cruzi | CMGC/DYRK protein kinase, putative | 0.0181 | 0.2494 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0102 | 0.072 | 0.072 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0088 | 0.0413 | 0.0413 |
Loa Loa (eye worm) | CMGC/CDK/CDC2 protein kinase | 0.0088 | 0.0413 | 0.0413 |
Loa Loa (eye worm) | CMGC/DYRK/DYRK1 protein kinase | 0.0181 | 0.2494 | 0.2494 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0102 | 0.072 | 0.1812 |
Entamoeba histolytica | hypothetical protein | 0.0181 | 0.2494 | 1 |
Entamoeba histolytica | protein kinase, putative | 0.0181 | 0.2494 | 1 |
Plasmodium falciparum | protein kinase 5 | 0.0088 | 0.0413 | 0.5 |
Entamoeba histolytica | protein kinase, putative | 0.0181 | 0.2494 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0516 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0247 | 0.3976 | 0.3976 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0088 | 0.0413 | 0.5 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0102 | 0.072 | 0.1812 |
Loa Loa (eye worm) | hypothetical protein | 0.0122 | 0.1182 | 0.1182 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.