Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0058 | 0.086 | 0.086 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0042 | 0.0274 | 0.1018 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0058 | 0.086 | 0.3201 |
Onchocerca volvulus | 0.0058 | 0.086 | 1 | |
Trypanosoma brucei | cysteine peptidase C (CPC) | 0.0109 | 0.2688 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0058 | 0.086 | 0.3201 |
Entamoeba histolytica | cysteine protease, putative | 0.0058 | 0.086 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0058 | 0.086 | 0.086 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0058 | 0.086 | 0.3201 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0058 | 0.086 | 0.086 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0042 | 0.0274 | 0.0274 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0058 | 0.086 | 0.3201 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0058 | 0.086 | 0.086 |
Brugia malayi | Cathepsin L-like precursor | 0.0058 | 0.086 | 0.086 |
Onchocerca volvulus | 0.0058 | 0.086 | 1 | |
Plasmodium vivax | vivapain-2 | 0.0058 | 0.086 | 1 |
Plasmodium vivax | vivapain-2 | 0.0058 | 0.086 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0058 | 0.086 | 0.3201 |
Brugia malayi | Cathepsin L-like precursor | 0.0058 | 0.086 | 0.086 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0058 | 0.086 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0109 | 0.2688 | 0.2688 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0058 | 0.086 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0058 | 0.086 | 0.3201 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0058 | 0.086 | 0.3201 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0058 | 0.086 | 0.3201 |
Onchocerca volvulus | Cathepsin F homolog | 0.0058 | 0.086 | 1 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0058 | 0.086 | 0.086 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0058 | 0.086 | 0.3201 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0058 | 0.086 | 0.3201 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0058 | 0.086 | 0.3201 |
Onchocerca volvulus | 0.0058 | 0.086 | 1 | |
Loa Loa (eye worm) | cysteine protease | 0.0058 | 0.086 | 0.0603 |
Loa Loa (eye worm) | ctsf protein | 0.0058 | 0.086 | 0.0603 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0058 | 0.086 | 0.086 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0042 | 0.0274 | 0.0274 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0058 | 0.086 | 0.086 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0058 | 0.086 | 0.086 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0058 | 0.086 | 0.086 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0058 | 0.086 | 0.3201 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0058 | 0.086 | 0.3201 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0058 | 0.086 | 0.3201 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0058 | 0.086 | 0.3201 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0058 | 0.086 | 0.086 |
Loa Loa (eye worm) | cathepsin B | 0.0109 | 0.2688 | 0.2482 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0058 | 0.086 | 0.086 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0058 | 0.086 | 0.3201 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0042 | 0.0274 | 0.3182 |
Echinococcus granulosus | cathepsin b | 0.0311 | 1 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0058 | 0.086 | 0.086 |
Loa Loa (eye worm) | fibroinase | 0.0058 | 0.086 | 0.0603 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0109 | 0.2688 | 1 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0058 | 0.086 | 0.086 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0058 | 0.086 | 0.086 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0058 | 0.086 | 0.3201 |
Leishmania major | cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like | 0.0109 | 0.2688 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0058 | 0.086 | 0.3201 |
Onchocerca volvulus | 0.0058 | 0.086 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0058 | 0.086 | 0.3201 |
Giardia lamblia | Cathepsin B precursor | 0.0109 | 0.2688 | 0.5 |
Brugia malayi | cathepsin L-like precursor | 0.0042 | 0.0274 | 0.0274 |
Echinococcus multilocularis | cysteine protease | 0.0058 | 0.086 | 0.086 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0058 | 0.086 | 0.3201 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0058 | 0.086 | 1 |
Onchocerca volvulus | Cathepsin L homolog | 0.0058 | 0.086 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0058 | 0.086 | 0.3201 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0058 | 0.086 | 0.0603 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0109 | 0.2688 | 0.2688 |
Echinococcus granulosus | cathepsin l1 | 0.0042 | 0.0274 | 0.0274 |
Echinococcus multilocularis | cathepsin b | 0.0311 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0058 | 0.086 | 0.3201 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0311 | 1 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0311 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0058 | 0.086 | 0.3201 |
Echinococcus multilocularis | cathepsin b | 0.0311 | 1 | 1 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0311 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0058 | 0.086 | 0.0603 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0058 | 0.086 | 0.3201 |
Loa Loa (eye worm) | hypothetical protein | 0.0311 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0058 | 0.086 | 0.3201 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0058 | 0.086 | 0.3201 |
Echinococcus granulosus | cathepsin b | 0.0311 | 1 | 1 |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.0311 | 1 | 1 |
Toxoplasma gondii | cathepsin B | 0.0109 | 0.2688 | 1 |
Onchocerca volvulus | 0.0058 | 0.086 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0058 | 0.086 | 0.3201 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0058 | 0.086 | 0.3201 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0058 | 0.086 | 0.3201 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0058 | 0.086 | 0.3201 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0058 | 0.086 | 0.3201 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0311 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0042 | 0.0274 | 0.1018 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0058 | 0.086 | 0.3201 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0058 | 0.086 | 0.3201 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0058 | 0.086 | 0.3201 |
Brugia malayi | Cathepsin L-like precursor | 0.0042 | 0.0274 | 0.0274 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0058 | 0.086 | 0.0603 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0058 | 0.086 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0058 | 0.086 | 0.3201 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0058 | 0.086 | 0.3201 |
Brugia malayi | Cathepsin L-like precursor | 0.0058 | 0.086 | 0.086 |
Brugia malayi | Cathepsin L-like precursor | 0.0058 | 0.086 | 0.086 |
Onchocerca volvulus | Cathepsin L homolog | 0.0058 | 0.086 | 1 |
Giardia lamblia | Cathepsin B precursor | 0.0109 | 0.2688 | 0.5 |
Echinococcus multilocularis | cysteine protease | 0.0058 | 0.086 | 0.086 |
Echinococcus granulosus | cathepsin l1 | 0.0058 | 0.086 | 0.086 |
Brugia malayi | Cathepsin L-like precursor | 0.0058 | 0.086 | 0.086 |
Brugia malayi | Cathepsin L-like precursor | 0.0042 | 0.0274 | 0.0274 |
Onchocerca volvulus | 0.0058 | 0.086 | 1 | |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0042 | 0.0274 | 0.0274 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0058 | 0.086 | 1 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0058 | 0.086 | 0.086 |
Giardia lamblia | Cathepsin B precursor | 0.0109 | 0.2688 | 0.5 |
Onchocerca volvulus | 0.0058 | 0.086 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.