Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Cathepsin L-like precursor | 0.0027 | 0.0343 | 0.0343 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0027 | 0.0343 | 0.0343 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0051 | 0.1072 | 0.1072 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0027 | 0.0343 | 0.0343 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0027 | 0.0343 | 0.0343 |
Onchocerca volvulus | 0.0027 | 0.0343 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0027 | 0.0343 | 0.0343 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0027 | 0.0343 | 0.086 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0027 | 0.0343 | 0.0343 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0027 | 0.0343 | 0.0343 |
Plasmodium vivax | macrophage migration inhibitory factor, putative | 0.0342 | 1 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0146 | 0.3989 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0027 | 0.0343 | 0.0343 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0027 | 0.0343 | 0.0343 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0027 | 0.0343 | 0.0343 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0051 | 0.1072 | 0.2688 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.002 | 0.0109 | 0.0109 |
Echinococcus granulosus | cathepsin b | 0.0146 | 0.3989 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0027 | 0.0343 | 0.3201 |
Echinococcus granulosus | cathepsin l1 | 0.002 | 0.0109 | 0.0274 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0027 | 0.0343 | 0.086 |
Onchocerca volvulus | 0.0027 | 0.0343 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0027 | 0.0343 | 0.0343 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0027 | 0.0343 | 0.0237 |
Echinococcus granulosus | cathepsin b | 0.0146 | 0.3989 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0027 | 0.0343 | 0.086 |
Plasmodium vivax | vivapain-2 | 0.0027 | 0.0343 | 0.0343 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0146 | 0.3989 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0027 | 0.0343 | 0.0343 |
Loa Loa (eye worm) | macrophage migration inhibitory factor 2 | 0.0146 | 0.3982 | 0.3916 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0027 | 0.0343 | 0.0343 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0027 | 0.0343 | 0.086 |
Loa Loa (eye worm) | ctsf protein | 0.0027 | 0.0343 | 0.0237 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0342 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0027 | 0.0343 | 0.3201 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0027 | 0.0343 | 0.0343 |
Onchocerca volvulus | Cathepsin L homolog | 0.0027 | 0.0343 | 1 |
Leishmania major | macrophage migration inhibitory factor-like protein | 0.0342 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0027 | 0.0343 | 0.0343 |
Loa Loa (eye worm) | cathepsin B | 0.0051 | 0.1072 | 0.0974 |
Toxoplasma gondii | macrophage migration inhibitory factor, putative | 0.0342 | 1 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0027 | 0.0343 | 0.0343 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0027 | 0.0343 | 0.0343 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0027 | 0.0343 | 0.0343 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0027 | 0.0343 | 0.086 |
Brugia malayi | Cathepsin L-like precursor | 0.0027 | 0.0343 | 0.0343 |
Leishmania major | cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like | 0.0051 | 0.1072 | 0.0755 |
Onchocerca volvulus | 0.0027 | 0.0343 | 1 | |
Entamoeba histolytica | macrophage migration inhibitory factor-like protein | 0.0342 | 1 | 1 |
Echinococcus multilocularis | cathepsin b | 0.0146 | 0.3989 | 1 |
Plasmodium falciparum | macrophage migration inhibitory factor | 0.0342 | 1 | 1 |
Loa Loa (eye worm) | cysteine protease | 0.0027 | 0.0343 | 0.0237 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0343 | 0.0237 |
Brugia malayi | Cathepsin L-like precursor | 0.0027 | 0.0343 | 0.0343 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0027 | 0.0343 | 0.0343 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0027 | 0.0343 | 0.3201 |
Onchocerca volvulus | Cathepsin F homolog | 0.0027 | 0.0343 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0027 | 0.0343 | 0.3201 |
Plasmodium vivax | vivapain-2 | 0.0027 | 0.0343 | 0.0343 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0027 | 0.0343 | 0.3201 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0027 | 0.0343 | 0.3201 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0027 | 0.0343 | 0.086 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0027 | 0.0343 | 0.0343 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0027 | 0.0343 | 0.0343 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0146 | 0.3989 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0027 | 0.0343 | 0.0343 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.002 | 0.0109 | 0.0109 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0027 | 0.0343 | 0.3201 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0027 | 0.0343 | 0.086 |
Brugia malayi | Cathepsin L-like precursor | 0.0027 | 0.0343 | 0.0343 |
Loa Loa (eye worm) | fibroinase | 0.0027 | 0.0343 | 0.0237 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0027 | 0.0343 | 0.0343 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0027 | 0.0343 | 0.086 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0027 | 0.0343 | 0.0343 |
Onchocerca volvulus | 0.0027 | 0.0343 | 1 | |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0027 | 0.0343 | 0.086 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0027 | 0.0343 | 0.0343 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0027 | 0.0343 | 0.3201 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0027 | 0.0343 | 0.0343 |
Onchocerca volvulus | 0.0027 | 0.0343 | 1 | |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0027 | 0.0343 | 0.0343 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0027 | 0.0343 | 0.3201 |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.0146 | 0.3989 | 1 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0027 | 0.0343 | 0.086 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0027 | 0.0343 | 0.0343 |
Trichomonas vaginalis | macrophage migration inhibitory factor, mif, putative | 0.0342 | 1 | 1 |
Toxoplasma gondii | cathepsin B | 0.0051 | 0.1072 | 0.0755 |
Giardia lamblia | Macrophage migration inhibitory factor | 0.0342 | 1 | 1 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0027 | 0.0343 | 0.086 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.002 | 0.0109 | 0.0109 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0027 | 0.0343 | 0.0343 |
Brugia malayi | Cathepsin L-like precursor | 0.002 | 0.0109 | 0.0109 |
Onchocerca volvulus | 0.0027 | 0.0343 | 1 | |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.002 | 0.0109 | 0.0274 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0051 | 0.1072 | 0.2688 |
Leishmania major | macrophage migration inhibitory factor-like protein | 0.0342 | 1 | 1 |
Echinococcus multilocularis | cathepsin b | 0.0146 | 0.3989 | 1 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0027 | 0.0343 | 0.086 |
Loa Loa (eye worm) | macrophage migration inhibitory factor 2 | 0.0146 | 0.3982 | 0.3916 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0027 | 0.0343 | 0.086 |
Brugia malayi | Cathepsin L-like precursor | 0.002 | 0.0109 | 0.0109 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0027 | 0.0343 | 0.0343 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0027 | 0.0343 | 0.0343 |
Loa Loa (eye worm) | macrophage migration inhibitory factor | 0.0342 | 1 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0146 | 0.3989 | 1 |
Trypanosoma brucei | cysteine peptidase C (CPC) | 0.0051 | 0.1072 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0027 | 0.0343 | 0.3201 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0027 | 0.0343 | 0.0237 |
Echinococcus granulosus | cathepsin l1 | 0.0027 | 0.0343 | 0.086 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.002 | 0.0109 | 0.0274 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0027 | 0.0343 | 0.0343 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0027 | 0.0343 | 0.3201 |
Brugia malayi | cathepsin B-like cysteine proteinase | 0.0146 | 0.3989 | 0.3989 |
Onchocerca volvulus | Cathepsin L homolog | 0.0027 | 0.0343 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0027 | 0.0343 | 0.0343 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0027 | 0.0343 | 0.0343 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0027 | 0.0343 | 0.0343 |
Brugia malayi | cathepsin L-like precursor | 0.002 | 0.0109 | 0.0109 |
Echinococcus multilocularis | cysteine protease | 0.0027 | 0.0343 | 0.086 |
Onchocerca volvulus | 0.0027 | 0.0343 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0146 | 0.3989 | 0.3923 |
Echinococcus multilocularis | cysteine protease | 0.0027 | 0.0343 | 0.086 |
Entamoeba histolytica | cysteine proteinase, putative | 0.002 | 0.0109 | 0.0109 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.