Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | P2X receptor subunit | 0.0199 | 0.3609 | 0.3609 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0086 | 0.086 | 0.3201 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0062 | 0.0274 | 0.3182 |
Giardia lamblia | Cathepsin B precursor | 0.0161 | 0.2688 | 0.5 |
Brugia malayi | Cathepsin L-like precursor | 0.0062 | 0.0274 | 0.0274 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0086 | 0.086 | 0.3201 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0086 | 0.086 | 0.3201 |
Plasmodium vivax | vivapain-2 | 0.0086 | 0.086 | 1 |
Echinococcus granulosus | p2X purinoceptor 4 | 0.0199 | 0.3609 | 0.3609 |
Onchocerca volvulus | 0.0086 | 0.086 | 1 | |
Giardia lamblia | Cathepsin B precursor | 0.0161 | 0.2688 | 0.5 |
Schistosoma mansoni | P2X receptor subunit | 0.0199 | 0.3609 | 0.3609 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0086 | 0.086 | 0.3201 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0086 | 0.086 | 0.3201 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0086 | 0.086 | 0.086 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0086 | 0.086 | 0.3201 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0086 | 0.086 | 0.3201 |
Onchocerca volvulus | Cathepsin L homolog | 0.0086 | 0.086 | 1 |
Schistosoma mansoni | P2X receptor subunit | 0.0199 | 0.3609 | 0.3609 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0086 | 0.086 | 0.3201 |
Loa Loa (eye worm) | hypothetical protein | 0.0086 | 0.086 | 0.0603 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0086 | 0.086 | 0.3201 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0086 | 0.086 | 0.3201 |
Echinococcus multilocularis | cathepsin b | 0.0462 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0086 | 0.086 | 0.3201 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0086 | 0.086 | 0.3201 |
Brugia malayi | Cathepsin L-like precursor | 0.0086 | 0.086 | 0.086 |
Loa Loa (eye worm) | ctsf protein | 0.0086 | 0.086 | 0.0603 |
Onchocerca volvulus | Cathepsin L homolog | 0.0086 | 0.086 | 1 |
Plasmodium vivax | vivapain-2 | 0.0086 | 0.086 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0086 | 0.086 | 0.3201 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0086 | 0.086 | 0.3201 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0086 | 0.086 | 0.3201 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0086 | 0.086 | 0.086 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0086 | 0.086 | 1 |
Trypanosoma brucei | cysteine peptidase C (CPC) | 0.0161 | 0.2688 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0086 | 0.086 | 0.3201 |
Brugia malayi | Cathepsin L-like precursor | 0.0062 | 0.0274 | 0.0274 |
Onchocerca volvulus | 0.0086 | 0.086 | 1 | |
Toxoplasma gondii | cathepsin B | 0.0161 | 0.2688 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0086 | 0.086 | 0.3201 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0086 | 0.086 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0086 | 0.086 | 0.086 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0086 | 0.086 | 0.3201 |
Echinococcus multilocularis | p2X purinoceptor 4 | 0.0199 | 0.3609 | 0.3609 |
Brugia malayi | Cathepsin L-like precursor | 0.0086 | 0.086 | 0.086 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0062 | 0.0274 | 0.0274 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0062 | 0.0274 | 0.0274 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0161 | 0.2688 | 0.2688 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0086 | 0.086 | 0.3201 |
Echinococcus multilocularis | cysteine protease | 0.0086 | 0.086 | 0.086 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0086 | 0.086 | 0.086 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0086 | 0.086 | 0.086 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0086 | 0.086 | 0.3201 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0086 | 0.086 | 0.3201 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0086 | 0.086 | 0.086 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0086 | 0.086 | 0.3201 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0086 | 0.086 | 0.3201 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0086 | 0.086 | 0.3201 |
Brugia malayi | Cathepsin L-like precursor | 0.0086 | 0.086 | 0.086 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0086 | 0.086 | 0.086 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0086 | 0.086 | 0.3201 |
Echinococcus multilocularis | p2X purinoceptor 4 | 0.0199 | 0.3609 | 0.3609 |
Brugia malayi | cathepsin L-like precursor | 0.0062 | 0.0274 | 0.0274 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0086 | 0.086 | 0.086 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0086 | 0.086 | 0.3201 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0086 | 0.086 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0086 | 0.086 | 0.086 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0086 | 0.086 | 0.3201 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0086 | 0.086 | 0.0603 |
Onchocerca volvulus | Cathepsin F homolog | 0.0086 | 0.086 | 1 |
Echinococcus granulosus | cathepsin l1 | 0.0086 | 0.086 | 0.086 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0086 | 0.086 | 0.3201 |
Echinococcus multilocularis | cysteine protease | 0.0086 | 0.086 | 0.086 |
Echinococcus granulosus | p2X purinoceptor 4 | 0.0199 | 0.3609 | 0.3609 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0086 | 0.086 | 0.3201 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0086 | 0.086 | 0.3201 |
Brugia malayi | Cathepsin L-like precursor | 0.0086 | 0.086 | 0.086 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0086 | 0.086 | 1 |
Onchocerca volvulus | 0.0086 | 0.086 | 1 | |
Echinococcus granulosus | p2X purinoceptor 4 | 0.0199 | 0.3609 | 0.3609 |
Echinococcus granulosus | cathepsin l1 | 0.0062 | 0.0274 | 0.0274 |
Onchocerca volvulus | 0.0086 | 0.086 | 1 | |
Leishmania major | cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like | 0.0161 | 0.2688 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0086 | 0.086 | 0.086 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0086 | 0.086 | 0.086 |
Loa Loa (eye worm) | fibroinase | 0.0086 | 0.086 | 0.0603 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0086 | 0.086 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0086 | 0.086 | 0.086 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0086 | 0.086 | 0.3201 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0161 | 0.2688 | 0.2688 |
Onchocerca volvulus | 0.0086 | 0.086 | 1 | |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0462 | 1 | 1 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0086 | 0.086 | 0.086 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0086 | 0.086 | 0.3201 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0062 | 0.0274 | 0.1018 |
Schistosoma mansoni | P2X receptor subunit | 0.0199 | 0.3609 | 0.3609 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0086 | 0.086 | 0.086 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0062 | 0.0274 | 0.0274 |
Giardia lamblia | Cathepsin B precursor | 0.0161 | 0.2688 | 0.5 |
Onchocerca volvulus | 0.0086 | 0.086 | 1 | |
Loa Loa (eye worm) | cysteine protease | 0.0086 | 0.086 | 0.0603 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0086 | 0.086 | 0.086 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0086 | 0.086 | 0.3201 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.0462 | 1 | 1 |
Echinococcus granulosus | cathepsin b | 0.0462 | 1 | 1 |
Loa Loa (eye worm) | cathepsin B | 0.0161 | 0.2688 | 0.2482 |
Echinococcus multilocularis | cathepsin b | 0.0462 | 1 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0462 | 1 | 1 |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.0462 | 1 | 1 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0086 | 0.086 | 0.086 |
Echinococcus granulosus | cathepsin b | 0.0462 | 1 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.0462 | 1 | 1 |
Onchocerca volvulus | 0.0086 | 0.086 | 1 | |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0086 | 0.086 | 0.3201 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.0161 | 0.2688 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0086 | 0.086 | 0.3201 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0086 | 0.086 | 0.0603 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0062 | 0.0274 | 0.1018 |
Echinococcus multilocularis | p2X purinoceptor 4 | 0.0199 | 0.3609 | 0.3609 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0086 | 0.086 | 0.3201 |
Loa Loa (eye worm) | hypothetical protein | 0.0462 | 1 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0086 | 0.086 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.