Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma brucei | DNA polymerase IV, putative | 0.0019 | 0 | 0.5 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0032 | 0.056 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.056 | 0.0648 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0 | 0.5 |
Leishmania major | DNA polymerase kappa, putative | 0.0019 | 0 | 0.5 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0019 | 0 | 0.5 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0032 | 0.056 | 1 |
Trypanosoma brucei | unspecified product | 0.0019 | 0 | 0.5 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0019 | 0 | 0.5 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0032 | 0.056 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0 | 0.5 |
Plasmodium vivax | mitochondrial ribosomal protein L41, putative | 0.0258 | 1 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0 | 0.5 |
Toxoplasma gondii | 60S ribosomal protein L27, putative | 0.0258 | 1 | 1 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.0019 | 0 | 0.5 |
Onchocerca volvulus | 0.0257 | 0.9956 | 1 | |
Leishmania major | DNA polymerase kappa, putative,DNA polymerase IV, putative | 0.0019 | 0 | 0.5 |
Brugia malayi | Pre-SET motif family protein | 0.0226 | 0.8651 | 1 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0019 | 0 | 0.5 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0 | 0.5 |
Entamoeba histolytica | deoxycytidyl transferase, putative | 0.0019 | 0 | 0.5 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0032 | 0.056 | 1 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0019 | 0 | 0.5 |
Mycobacterium tuberculosis | Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) | 0.0019 | 0 | 0.5 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0032 | 0.056 | 1 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0032 | 0.056 | 1 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0019 | 0 | 0.5 |
Giardia lamblia | DINP protein human, muc B family | 0.0019 | 0 | 0.5 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0032 | 0.056 | 1 |
Trichomonas vaginalis | set domain proteins, putative | 0.0257 | 0.9956 | 1 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0031 | 0.051 | 0.911 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0226 | 0.8651 | 1 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0019 | 0 | 0.5 |
Leishmania major | DNA polymerase eta, putative | 0.0019 | 0 | 0.5 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0 | 0.5 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0 | 0.5 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0019 | 0 | 0.5 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0 | 0.5 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0019 | 0 | 0.5 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0019 | 0 | 0.5 |
Brugia malayi | Pre-SET motif family protein | 0.0032 | 0.056 | 0.0648 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0 | 0.5 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0 | 0.5 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0019 | 0 | 0.5 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0019 | 0 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.