Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.3199 | 0.8214 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.3705 | 1 | 1 |
Onchocerca volvulus | Cathepsin L homolog | 0.1572 | 0.247 | 1 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.1572 | 0.247 | 0.3007 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.3705 | 1 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.1572 | 0.247 | 0.3007 |
Schistosoma mansoni | SmCB2 peptidase (C01 family) | 0.3199 | 0.8214 | 1 |
Brugia malayi | cathepsin L-like precursor | 0.1095 | 0.0786 | 0.0957 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1572 | 0.247 | 0.8579 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1572 | 0.247 | 0.8579 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.1095 | 0.0786 | 0.0957 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.3228 | 0.8316 | 0.8316 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1572 | 0.247 | 0.8579 |
Brugia malayi | Cathepsin L-like precursor | 0.1572 | 0.247 | 0.3007 |
Brugia malayi | Cathepsin L-like precursor | 0.1572 | 0.247 | 0.3007 |
Onchocerca volvulus | 0.1572 | 0.247 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1572 | 0.247 | 0.8579 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1572 | 0.247 | 0.8579 |
Onchocerca volvulus | Cathepsin L homolog | 0.1572 | 0.247 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.1095 | 0.0786 | 0.0957 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.1572 | 0.247 | 0.3007 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.1572 | 0.247 | 0.3007 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1572 | 0.247 | 0.8579 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1572 | 0.247 | 0.8579 |
Toxoplasma gondii | cathepsin B | 0.1688 | 0.2879 | 1 |
Giardia lamblia | Cathepsin B precursor | 0.1688 | 0.2879 | 0.5 |
Leishmania major | cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like | 0.1688 | 0.2879 | 0.0543 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.3705 | 1 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.1572 | 0.247 | 0.3007 |
Trypanosoma brucei | cysteine peptidase C (CPC) | 0.1688 | 0.2879 | 0.2879 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.1572 | 0.247 | 0.3007 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.3705 | 1 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.1572 | 0.247 | 1 |
Loa Loa (eye worm) | fibroinase | 0.1572 | 0.247 | 0.2267 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.1688 | 0.2879 | 0.3505 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1572 | 0.247 | 0.8579 |
Echinococcus granulosus | cathepsin l1 | 0.1572 | 0.247 | 0.3007 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.3705 | 1 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.1572 | 0.247 | 0.247 |
Plasmodium vivax | vivapain-2 | 0.1572 | 0.247 | 1 |
Echinococcus granulosus | cathepsin b | 0.3199 | 0.8214 | 1 |
Trypanosoma cruzi | major cysteine proteinase, putative | 0.2529 | 0.5846 | 0.5846 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1572 | 0.247 | 0.8579 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.1572 | 0.247 | 0.2267 |
Brugia malayi | cathepsin B-like cysteine proteinase | 0.3199 | 0.8214 | 1 |
Giardia lamblia | Cathepsin B precursor | 0.1688 | 0.2879 | 0.5 |
Entamoeba histolytica | cysteine proteinase, putative | 0.1572 | 0.247 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1572 | 0.247 | 0.8579 |
Loa Loa (eye worm) | cathepsin B | 0.1688 | 0.2879 | 0.2818 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.3705 | 1 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.1572 | 0.247 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.1572 | 0.247 | 0.3007 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1095 | 0.0786 | 0.273 |
Echinococcus multilocularis | cysteine protease | 0.1572 | 0.247 | 0.3007 |
Onchocerca volvulus | Cathepsin F homolog | 0.1572 | 0.247 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1572 | 0.247 | 0.2267 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1095 | 0.0786 | 0.273 |
Echinococcus multilocularis | cysteine protease | 0.1572 | 0.247 | 0.3007 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1572 | 0.247 | 0.8579 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1572 | 0.247 | 0.8579 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.1572 | 0.247 | 0.3007 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1572 | 0.247 | 0.8579 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1572 | 0.247 | 0.8579 |
Brugia malayi | Cathepsin L-like precursor | 0.1572 | 0.247 | 0.3007 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.1572 | 0.247 | 0.3007 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.1572 | 0.247 | 0.3007 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.1572 | 0.247 | 0.8579 |
Loa Loa (eye worm) | hypothetical protein | 0.3199 | 0.8214 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1572 | 0.247 | 0.8579 |
Entamoeba histolytica | cysteine proteinase, putative | 0.1095 | 0.0786 | 0.3182 |
Loa Loa (eye worm) | ctsf protein | 0.1572 | 0.247 | 0.2267 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.1572 | 0.247 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1572 | 0.247 | 0.8579 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1572 | 0.247 | 0.8579 |
Onchocerca volvulus | 0.1572 | 0.247 | 1 | |
Onchocerca volvulus | 0.1572 | 0.247 | 1 | |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.3705 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1572 | 0.247 | 0.8579 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.1572 | 0.247 | 0.2267 |
Echinococcus multilocularis | cathepsin b | 0.3199 | 0.8214 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin B-like cysteine peptidase | 0.1688 | 0.2879 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.3705 | 1 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.1572 | 0.247 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1572 | 0.247 | 0.8579 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.3199 | 0.8214 | 0.8214 |
Plasmodium vivax | vivapain-2 | 0.1572 | 0.247 | 1 |
Echinococcus granulosus | cathepsin l1 | 0.1095 | 0.0786 | 0.0957 |
Loa Loa (eye worm) | cysteine protease | 0.1572 | 0.247 | 0.2267 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1572 | 0.247 | 0.8579 |
Brugia malayi | Cathepsin L-like precursor | 0.1572 | 0.247 | 0.3007 |
Onchocerca volvulus | 0.1572 | 0.247 | 1 | |
Onchocerca volvulus | 0.1572 | 0.247 | 1 | |
Brugia malayi | Papain family cysteine protease containing protein | 0.1572 | 0.247 | 0.3007 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.3705 | 1 | 1 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.3199 | 0.8214 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.3705 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.3705 | 1 | 1 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.1095 | 0.0786 | 0.0957 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.3705 | 1 | 1 |
Onchocerca volvulus | 0.1572 | 0.247 | 1 | |
Echinococcus granulosus | cathepsin b | 0.3199 | 0.8214 | 1 |
Giardia lamblia | Cathepsin B precursor | 0.1688 | 0.2879 | 0.5 |
Entamoeba histolytica | cysteine proteinase, putative | 0.1572 | 0.247 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.1572 | 0.247 | 0.8579 |
Schistosoma mansoni | cathepsin B-like peptidase (C01 family) | 0.3199 | 0.8214 | 1 |
Trypanosoma cruzi | cysteine peptidase C (CPC), putative | 0.1688 | 0.2879 | 0.2879 |
Brugia malayi | Cathepsin L-like precursor | 0.1095 | 0.0786 | 0.0957 |
Onchocerca volvulus | 0.1572 | 0.247 | 1 | |
Echinococcus multilocularis | cathepsin b | 0.3199 | 0.8214 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.3705 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1572 | 0.247 | 0.8579 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.1572 | 0.247 | 0.8579 |
Leishmania major | cathepsin L-like protease | 0.3705 | 1 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.3705 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.1572 | 0.247 | 0.8579 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.3705 | 1 | 1 |
Leishmania major | cathepsin L-like protease | 0.3705 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.