Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0072 | 0.4849 | 0.4849 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0072 | 0.4849 | 0.4849 |
Trichomonas vaginalis | AGC family protein kinase | 0.0077 | 0.603 | 1 |
Echinococcus multilocularis | cAMP dependent protein kinase catalytic subunit | 0.0077 | 0.603 | 0.603 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0072 | 0.4849 | 0.4849 |
Loa Loa (eye worm) | AGC/PKA protein kinase | 0.0077 | 0.603 | 0.2292 |
Trypanosoma brucei | cAMP-dependent protein kinase catalytic subunit 1 | 0.0077 | 0.603 | 1 |
Echinococcus granulosus | cAMP specific 3'5' cyclic phosphodiesterase | 0.0094 | 1 | 1 |
Giardia lamblia | CAMP-specific 3,5-cyclic phosphodiesterase 4B | 0.0094 | 1 | 1 |
Trypanosoma brucei | cAMP-dependent protein kinase catalytic subunit 2 | 0.0077 | 0.603 | 1 |
Echinococcus granulosus | enhancer of mRNA decapping protein 4 | 0.0076 | 0.5825 | 0.5825 |
Echinococcus multilocularis | cAMP specific 3',5' cyclic phosphodiesterase | 0.0094 | 1 | 1 |
Echinococcus multilocularis | cAMP specific 3',5' cyclic phosphodiesterase | 0.0082 | 0.7335 | 0.7335 |
Leishmania major | protein kinase A catalytic subunit | 0.0077 | 0.603 | 1 |
Loa Loa (eye worm) | cyclic AMP specific phosphodiesterase PDE4D5A | 0.0082 | 0.7335 | 0.4826 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.603 | 0.2292 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0072 | 0.4849 | 0.4849 |
Echinococcus multilocularis | aldo keto reductase | 0.0072 | 0.4849 | 0.4849 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0072 | 0.4849 | 0.4849 |
Echinococcus granulosus | aldo keto reductase | 0.0072 | 0.4849 | 0.4849 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0072 | 0.4849 | 0.4849 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0077 | 0.603 | 0.2292 |
Echinococcus multilocularis | aldo keto reductase | 0.0072 | 0.4849 | 0.4849 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0072 | 0.4849 | 0.4849 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0072 | 0.4849 | 0.4849 |
Trypanosoma cruzi | cAMP-dependent protein kinase catalytic subunit 1 | 0.0077 | 0.603 | 1 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0072 | 0.4849 | 0.4849 |
Onchocerca volvulus | 0.0072 | 0.4849 | 0.5 | |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0072 | 0.4849 | 0.4849 |
Echinococcus granulosus | cAMP dependent protein kinase catalytic subunit | 0.0077 | 0.603 | 0.603 |
Onchocerca volvulus | 0.0072 | 0.4849 | 0.5 | |
Entamoeba histolytica | PH domain containing protein kinase, putative | 0.0077 | 0.603 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 1 | 1 |
Trypanosoma cruzi | cAMP-dependent protein kinase catalytic subunit 2 | 0.0077 | 0.603 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0077 | 0.603 | 0.2292 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0072 | 0.4849 | 0.4849 |
Loa Loa (eye worm) | AGC/PKA protein kinase | 0.0077 | 0.603 | 0.2292 |
Leishmania major | protein kinase A catalytic subunit isoform 2 | 0.0077 | 0.603 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0077 | 0.603 | 0.2292 |
Echinococcus granulosus | cAMP specific 3'5' cyclic phosphodiesterase | 0.0082 | 0.7335 | 0.7335 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0072 | 0.4849 | 0.4849 |
Echinococcus multilocularis | enhancer of mRNA decapping protein 4 | 0.0076 | 0.5825 | 0.5825 |
Echinococcus granulosus | cAMP dependent protein kinase catalytic subunit | 0.0077 | 0.603 | 0.603 |
Toxoplasma gondii | protein kinase, cAMP-dependent, catalytic chain | 0.0077 | 0.603 | 0.2292 |
Toxoplasma gondii | 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein | 0.0094 | 1 | 1 |
Leishmania major | protein kinase A catalytic subunit isoform 1 | 0.0077 | 0.603 | 1 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0072 | 0.4849 | 0.4849 |
Plasmodium falciparum | cAMP-dependent protein kinase catalytic subunit | 0.0077 | 0.603 | 0.5 |
Echinococcus multilocularis | cAMP dependent protein kinase catalytic subunit | 0.0077 | 0.603 | 0.603 |
Schistosoma mansoni | camp-specific 35-cyclic phosphodiesterase | 0.0094 | 1 | 1 |
Toxoplasma gondii | AGC kinase | 0.0077 | 0.603 | 0.2292 |
Echinococcus multilocularis | cAMP dependent protein kinase catalytic subunit | 0.0077 | 0.603 | 0.603 |
Plasmodium vivax | cAMP-dependent protein kinase catalytic subunit, putative | 0.0077 | 0.603 | 0.5 |
Trypanosoma cruzi | cAMP-dependent protein kinase catalytic subunit 3 | 0.0077 | 0.603 | 1 |
Echinococcus multilocularis | cAMP dependent protein kinase catalytic subunit | 0.0077 | 0.603 | 0.603 |
Onchocerca volvulus | 0.0072 | 0.4849 | 0.5 | |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0072 | 0.4849 | 0.4849 |
Echinococcus multilocularis | aldo keto reductase | 0.0072 | 0.4849 | 0.4849 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0072 | 0.4849 | 0.4849 |
Echinococcus granulosus | cAMP dependent protein kinase catalytic subunit | 0.0077 | 0.603 | 0.603 |
Echinococcus multilocularis | aldo keto reductase | 0.0072 | 0.4849 | 0.4849 |
Onchocerca volvulus | 0.0072 | 0.4849 | 0.5 | |
Giardia lamblia | Kinase, AGC PKA | 0.0077 | 0.603 | 0.2292 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0072 | 0.4849 | 0.4849 |
Mycobacterium ulcerans | oxidoreductase | 0.0072 | 0.4849 | 0.5 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0072 | 0.4849 | 0.4849 |
Trypanosoma cruzi | cAMP-dependent protein kinase catalytic subunit 3 | 0.0077 | 0.603 | 1 |
Echinococcus granulosus | aldo keto reductase | 0.0072 | 0.4849 | 0.4849 |
Onchocerca volvulus | 0.0072 | 0.4849 | 0.5 | |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0072 | 0.4849 | 0.4849 |
Mycobacterium leprae | PROBABLE OXIDOREDUCTASE | 0.0072 | 0.4849 | 1 |
Echinococcus multilocularis | aldo keto reductase family 1, member B4 | 0.0072 | 0.4849 | 0.4849 |
Echinococcus granulosus | hypothetical protein | 0.0072 | 0.4849 | 0.4849 |
Echinococcus granulosus | aldo keto reductase family 1 member B4 | 0.0072 | 0.4849 | 0.4849 |
Trypanosoma brucei | protein kinase A catalytic subunit, putative | 0.0077 | 0.603 | 1 |
Brugia malayi | cAMP-dependent protein kinase catalytic subunit, putative | 0.0077 | 0.603 | 0.4748 |
Onchocerca volvulus | 0.0072 | 0.4849 | 0.5 | |
Echinococcus granulosus | aldo keto reductase | 0.0072 | 0.4849 | 0.4849 |
Toxoplasma gondii | AGC kinase | 0.0077 | 0.603 | 0.2292 |
Brugia malayi | Probable 3',5'-cyclic phosphodiesterase R153.1, putative | 0.0082 | 0.7335 | 1 |
Echinococcus multilocularis | cAMP specific 3',5' cyclic phosphodiesterase | 0.0094 | 1 | 1 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0072 | 0.4849 | 0.5 |
Entamoeba histolytica | PH domain containing protein kinase, putative | 0.0077 | 0.603 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.