Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma cruzi | cdc2-related kinase 1 | 0.0044 | 0 | 0.5 |
Giardia lamblia | Kinase, CMGC CDK | 0.0044 | 0 | 0.5 |
Giardia lamblia | Kinase, CMGC CDK | 0.0044 | 0 | 0.5 |
Echinococcus granulosus | 5'partial|cyclin dependent kinase 1 | 0.0044 | 0 | 0.5 |
Brugia malayi | cell division control protein 2 homolog | 0.0044 | 0 | 0.5 |
Mycobacterium ulcerans | dihydropteroate synthase 1 FolP1 | 0.0954 | 1 | 1 |
Plasmodium falciparum | hydroxymethyldihydropterin pyrophosphokinase-dihydropteroate synthase | 0.0954 | 1 | 1 |
Echinococcus granulosus | cyclin dependent kinase | 0.0044 | 0 | 0.5 |
Echinococcus multilocularis | cyclin dependent kinase 1 | 0.0044 | 0 | 0.5 |
Trypanosoma cruzi | cdc2-related kinase 1 | 0.0044 | 0 | 0.5 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0044 | 0 | 0.5 |
Plasmodium vivax | hydroxymethylpterin pyrophosphokinase-dihydropteroate synthetase, putative | 0.0954 | 1 | 1 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0044 | 0 | 0.5 |
Echinococcus multilocularis | cyclin dependent kinase | 0.0044 | 0 | 0.5 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0044 | 0 | 0.5 |
Trypanosoma brucei | cdc2-related kinase 1 | 0.0044 | 0 | 0.5 |
Loa Loa (eye worm) | CMGC/CDK/CDK5 protein kinase | 0.0044 | 0 | 0.5 |
Toxoplasma gondii | dihydropteroate synthase | 0.0954 | 1 | 1 |
Mycobacterium tuberculosis | Dihydropteroate synthase 1 FolP (DHPS 1) (dihydropteroate pyrophosphorylase 1) (dihydropteroate diphosphorylase 1) | 0.0954 | 1 | 1 |
Mycobacterium leprae | Probable dihydropteroate synthase 1 FolP1 (DHPS 1) (dihydropteroate pyrophosphorylase 1) (dihydropteroate dipyrophosphorylase 1) | 0.0954 | 1 | 1 |
Trypanosoma cruzi | cdc2-related kinase 3 | 0.0044 | 0 | 0.5 |
Entamoeba histolytica | cell division protein kinase 2, putative | 0.0044 | 0 | 0.5 |
Loa Loa (eye worm) | CMGC/CDK/CDC2 protein kinase | 0.0044 | 0 | 0.5 |
Entamoeba histolytica | cell division protein kinase 2, putative | 0.0044 | 0 | 0.5 |
Trypanosoma cruzi | cdc2-related kinase 3 | 0.0044 | 0 | 0.5 |
Loa Loa (eye worm) | CMGC/CDK/CDC2 protein kinase | 0.0044 | 0 | 0.5 |
Leishmania major | methionine synthase, putative | 0.0351 | 0.3376 | 1 |
Brugia malayi | Protein kinase domain containing protein | 0.0044 | 0 | 0.5 |
Echinococcus granulosus | cyclin dependent kinase 5 | 0.0044 | 0 | 0.5 |
Echinococcus multilocularis | cyclin dependent kinase 5 | 0.0044 | 0 | 0.5 |
Echinococcus multilocularis | cyclin dependent kinase 1 | 0.0044 | 0 | 0.5 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0044 | 0 | 0.5 |
Trichomonas vaginalis | CMGC family protein kinase | 0.0044 | 0 | 0.5 |
Echinococcus granulosus | cyclin dependent kinase 1 | 0.0044 | 0 | 0.5 |
Trypanosoma brucei | cdc2-related kinase 3 | 0.0044 | 0 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.