Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0166 | 0.0897 | 0.0897 |
Schistosoma mansoni | thyroid hormone receptor | 0.0197 | 0.2026 | 0.2026 |
Trypanosoma brucei | lipase domain protein, putative | 0.029 | 0.5464 | 0.5 |
Schistosoma mansoni | thyroid hormone receptor | 0.0197 | 0.2026 | 0.2026 |
Echinococcus granulosus | fatty acid amide hydrolase 1 | 0.0413 | 1 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.029 | 0.5464 | 0.5 |
Echinococcus multilocularis | fatty acid amide hydrolase 1 | 0.0413 | 1 | 1 |
Echinococcus granulosus | sn1 specific diacylglycerol lipase beta | 0.029 | 0.5464 | 0.5464 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.029 | 0.5464 | 0.5 |
Schistosoma mansoni | amidase | 0.0413 | 1 | 1 |
Schistosoma mansoni | fatty-acid amide hydrolase | 0.0413 | 1 | 1 |
Leishmania major | hypothetical protein, conserved | 0.029 | 0.5464 | 0.5 |
Echinococcus granulosus | fatty acid amide hydrolase 1 | 0.0413 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0413 | 1 | 1 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0197 | 0.2026 | 0.2026 |
Echinococcus multilocularis | tumor protein p63 | 0.038 | 0.8765 | 0.8765 |
Trichomonas vaginalis | lipase containing protein, putative | 0.029 | 0.5464 | 0.5 |
Trypanosoma brucei | lipase domain protein, putative | 0.029 | 0.5464 | 0.5 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0166 | 0.0897 | 0.0897 |
Echinococcus multilocularis | sn1 specific diacylglycerol lipase beta | 0.029 | 0.5464 | 0.5464 |
Echinococcus multilocularis | fatty acid amide hydrolase 1 | 0.0413 | 1 | 1 |
Onchocerca volvulus | 0.029 | 0.5464 | 0.5 | |
Trichomonas vaginalis | lipase containing protein, putative | 0.029 | 0.5464 | 0.5 |
Echinococcus granulosus | tumor protein p63 | 0.038 | 0.8765 | 0.8765 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.