Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | solute carrier family 2 facilitated glucose | 0.0117 | 1 | 1 |
Leishmania major | glucose transporter, lmgt2 | 0.0036 | 0 | 0.5 |
Schistosoma mansoni | glucose transport protein | 0.0117 | 1 | 0.5 |
Trypanosoma cruzi | hexose transporter, putative | 0.0036 | 0 | 0.5 |
Echinococcus granulosus | solute carrier family 2 facilitated glucose | 0.0117 | 1 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0117 | 1 | 1 |
Trypanosoma brucei | THT1 - hexose transporter, putative | 0.0036 | 0 | 0.5 |
Trypanosoma brucei | THT1 - hexose transporter, putative | 0.0036 | 0 | 0.5 |
Trypanosoma brucei | glucose transporter, putative | 0.0036 | 0 | 0.5 |
Plasmodium vivax | hexose transporter | 0.0117 | 1 | 0.5 |
Echinococcus multilocularis | solute carrier family 2 facilitated glucose | 0.0117 | 1 | 1 |
Toxoplasma gondii | facilitative glucose transporter GT1 | 0.0117 | 1 | 0.5 |
Trypanosoma brucei | glucose transporter, putative | 0.0036 | 0 | 0.5 |
Schistosoma mansoni | glucose transport protein | 0.0117 | 1 | 0.5 |
Trypanosoma brucei | glucose transporter 2A | 0.0036 | 0 | 0.5 |
Leishmania major | glucose transporter, lmgt1 | 0.0036 | 0 | 0.5 |
Trypanosoma cruzi | hexose transporter, putative | 0.0036 | 0 | 0.5 |
Trypanosoma brucei | glucose transporter, putative | 0.0036 | 0 | 0.5 |
Trypanosoma brucei | glucose transporter, putative | 0.0036 | 0 | 0.5 |
Trypanosoma cruzi | hexose transporter | 0.0036 | 0 | 0.5 |
Leishmania major | glucose transporter/membrane transporter D2, putative | 0.0036 | 0 | 0.5 |
Echinococcus granulosus | solute carrier family 2 facilitated glucose | 0.0117 | 1 | 1 |
Echinococcus multilocularis | solute carrier family 2 facilitated glucose | 0.0117 | 1 | 1 |
Echinococcus multilocularis | solute carrier family 2, facilitated glucose | 0.0117 | 1 | 1 |
Trypanosoma brucei | glucose transporter, putative | 0.0036 | 0 | 0.5 |
Schistosoma mansoni | glucose transport protein | 0.0117 | 1 | 0.5 |
Trypanosoma brucei | THT1 - hexose transporter, putative | 0.0036 | 0 | 0.5 |
Echinococcus granulosus | solute carrier family 2 facilitated glucose | 0.0117 | 1 | 1 |
Trypanosoma brucei | glucose transporter, putative | 0.0036 | 0 | 0.5 |
Plasmodium falciparum | hexose transporter | 0.0117 | 1 | 0.5 |
Trypanosoma brucei | glucose transporter, putative | 0.0036 | 0 | 0.5 |
Leishmania major | glucose transporter, lmgt3 | 0.0036 | 0 | 0.5 |
Loa Loa (eye worm) | sugar transporter | 0.0117 | 1 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0117 | 1 | 0.5 |
Trypanosoma brucei | glucose transporter, putative | 0.0036 | 0 | 0.5 |
Echinococcus granulosus | solute carrier family 2 facilitated glucose | 0.0117 | 1 | 1 |
Trypanosoma brucei | glucose transporter 1E | 0.0036 | 0 | 0.5 |
Trypanosoma cruzi | hexose transporter, putative | 0.0036 | 0 | 0.5 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
EC50 (binding) | > 100 uM | Agonist activity at NTSR1 (unknown origin) expressed in CHO cells assessed as potentiation of NT(8-13) peptide-induced change in intracellular Ca2+ level preincubated for 45 mins by FLIPR assay | ChEMBL. | 24997685 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.