Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Entamoeba histolytica | cysteine protease, putative | 0.018 | 0.045 | 0.1626 |
Entamoeba histolytica | cysteine proteinase, putative | 0.018 | 0.045 | 0.1626 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0349 | 0.2769 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0349 | 0.2769 | 1 |
Echinococcus granulosus | cathepsin l cysteine peptidase | 0.0349 | 0.2769 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.018 | 0.045 | 0.1626 |
Brugia malayi | Papain family cysteine protease containing protein | 0.0349 | 0.2769 | 1 |
Echinococcus multilocularis | cysteine protease | 0.0349 | 0.2769 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0349 | 0.2769 | 1 |
Leishmania major | cathepsin L-like protease | 0.0877 | 1 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0349 | 0.2769 | 1 |
Onchocerca volvulus | Cathepsin L homolog | 0.0349 | 0.2769 | 1 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0349 | 0.2769 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 3 | 0.0349 | 0.2769 | 1 |
Plasmodium falciparum | cysteine proteinase falcipain 2b | 0.0349 | 0.2769 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0877 | 1 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0349 | 0.2769 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.018 | 0.045 | 0.1626 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0349 | 0.2769 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0234 | 0.1188 | 0.4291 |
Echinococcus multilocularis | cathepsin l cysteine peptidase | 0.0349 | 0.2769 | 1 |
Echinococcus multilocularis | cathepsin L | 0.018 | 0.045 | 0.1626 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0349 | 0.2769 | 1 |
Onchocerca volvulus | 0.0349 | 0.2769 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0349 | 0.2769 | 1 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.018 | 0.045 | 0.1626 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0877 | 1 | 1 |
Entamoeba histolytica | cysteine proteinase 1, putative | 0.018 | 0.045 | 0.1626 |
Onchocerca volvulus | Cathepsin L homolog | 0.0349 | 0.2769 | 1 |
Leishmania major | cathepsin L-like protease | 0.0877 | 1 | 1 |
Loa Loa (eye worm) | ctsf protein | 0.0349 | 0.2769 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0234 | 0.1188 | 0.4291 |
Onchocerca volvulus | Cathepsin F homolog | 0.0349 | 0.2769 | 1 |
Schistosoma mansoni | cathepsin F (C01 family) | 0.0349 | 0.2769 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0234 | 0.1188 | 0.3182 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0877 | 1 | 1 |
Echinococcus granulosus | cathepsin L | 0.018 | 0.045 | 0.1626 |
Echinococcus granulosus | cathepsin L cysteine proteinase | 0.0349 | 0.2769 | 1 |
Trypanosoma cruzi | cysteine peptidase, clan CA, family C1, cathepsin L-like, putative | 0.0762 | 0.8419 | 0.8345 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0877 | 1 | 1 |
Echinococcus granulosus | cathepsin l1 | 0.0234 | 0.1188 | 0.4291 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0877 | 1 | 1 |
Entamoeba histolytica | cysteine proteinase 2 | 0.018 | 0.045 | 0.1626 |
Brugia malayi | Papain family cysteine protease containing protein | 0.018 | 0.045 | 0.1626 |
Entamoeba histolytica | cysteine proteinase, putative | 0.018 | 0.045 | 0.1626 |
Entamoeba histolytica | cysteine protease, putative | 0.018 | 0.045 | 0.1626 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0877 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0349 | 0.2769 | 1 |
Loa Loa (eye worm) | cysteine protease | 0.0349 | 0.2769 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0349 | 0.2769 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.018 | 0.045 | 0.1626 |
Echinococcus granulosus | cysteine protease | 0.018 | 0.045 | 0.1626 |
Brugia malayi | Cathepsin L-like precursor | 0.0349 | 0.2769 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0349 | 0.2769 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0349 | 0.2769 | 1 |
Trypanosoma cruzi | cruzipain precursor, putative | 0.0877 | 1 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.0349 | 0.2769 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.018 | 0.045 | 0.1626 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.018 | 0.045 | 0.1626 |
Onchocerca volvulus | 0.0349 | 0.2769 | 1 | |
Onchocerca volvulus | 0.0349 | 0.2769 | 1 | |
Entamoeba histolytica | cysteine protease, putative | 0.018 | 0.045 | 0.1626 |
Brugia malayi | Papain family cysteine protease containing protein | 0.018 | 0.045 | 0.1626 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0349 | 0.2769 | 1 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0349 | 0.2769 | 0.2428 |
Toxoplasma gondii | cathepsin CPL | 0.0349 | 0.2769 | 0.5 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0349 | 0.2769 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.018 | 0.045 | 0.1626 |
Trypanosoma cruzi | cysteine peptidase, putative | 0.0877 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0349 | 0.2769 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L or K-like cysteine peptidase | 0.0349 | 0.2769 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.018 | 0.045 | 0.1626 |
Brugia malayi | Cathepsin L-like precursor | 0.0349 | 0.2769 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0877 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0349 | 0.2769 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0877 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0349 | 0.2769 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0349 | 0.2769 | 1 |
Onchocerca volvulus | 0.0349 | 0.2769 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0349 | 0.2769 | 1 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0349 | 0.2769 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0349 | 0.2769 | 1 |
Echinococcus multilocularis | cathepsin L cysteine protease | 0.0349 | 0.2769 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0349 | 0.2769 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0349 | 0.2769 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0349 | 0.2769 | 1 |
Loa Loa (eye worm) | papain family cysteine protease containing protein | 0.0349 | 0.2769 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0877 | 1 | 1 |
Trichomonas vaginalis | Clan CA, family C1, papain-like cysteine peptidase | 0.0349 | 0.2769 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0349 | 0.2769 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0234 | 0.1188 | 0.3182 |
Brugia malayi | Cathepsin L-like precursor | 0.0349 | 0.2769 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0234 | 0.1188 | 0.4291 |
Entamoeba histolytica | cysteine protease, putative | 0.018 | 0.045 | 0.1626 |
Entamoeba histolytica | cysteine protease, putative | 0.018 | 0.045 | 0.1626 |
Brugia malayi | cathepsin L-like precursor | 0.0234 | 0.1188 | 0.4291 |
Plasmodium vivax | vivapain-2 | 0.0349 | 0.2769 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.018 | 0.045 | 0.1626 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0877 | 1 | 1 |
Entamoeba histolytica | cysteine protease, putative | 0.018 | 0.045 | 0.1626 |
Echinococcus multilocularis | cysteine protease | 0.0349 | 0.2769 | 1 |
Entamoeba histolytica | cysteine proteinase, putative | 0.0349 | 0.2769 | 1 |
Plasmodium vivax | vivapain-2 | 0.0349 | 0.2769 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0349 | 0.2769 | 1 |
Loa Loa (eye worm) | fibroinase | 0.0349 | 0.2769 | 1 |
Trypanosoma cruzi | major cysteine proteinase, putative | 0.0592 | 0.61 | 0.5917 |
Loa Loa (eye worm) | Papain cysteine protease/cathepsin propeptide inhibitor-containing protein | 0.0349 | 0.2769 | 1 |
Echinococcus granulosus | cathepsin l1 | 0.0349 | 0.2769 | 1 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0877 | 1 | 1 |
Onchocerca volvulus | 0.0349 | 0.2769 | 1 | |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0877 | 1 | 1 |
Brugia malayi | Cathepsin L-like cysteine proteinase | 0.0234 | 0.1188 | 0.4291 |
Plasmodium falciparum | cysteine proteinase falcipain 2a | 0.0349 | 0.2769 | 1 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0349 | 0.2769 | 1 |
Schistosoma mansoni | SmCL2-like peptidase (C01 family) | 0.018 | 0.045 | 0.1626 |
Trypanosoma brucei | cysteine peptidase, Clan CA, family C1, Cathepsin L-like | 0.0877 | 1 | 1 |
Echinococcus granulosus | cathepsin L cysteine protease | 0.018 | 0.045 | 0.1626 |
Brugia malayi | Cathepsin L-like precursor | 0.0234 | 0.1188 | 0.4291 |
Entamoeba histolytica | cysteine proteinase, putative | 0.018 | 0.045 | 0.1626 |
Entamoeba histolytica | cysteine protease, putative | 0.018 | 0.045 | 0.1626 |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0349 | 0.2769 | 1 |
Brugia malayi | Cathepsin L-like precursor | 0.0349 | 0.2769 | 1 |
Onchocerca volvulus | 0.0349 | 0.2769 | 1 | |
Onchocerca volvulus | 0.0349 | 0.2769 | 1 | |
Trichomonas vaginalis | Clan CA, family C1, cathepsin L-like cysteine peptidase | 0.0349 | 0.2769 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.