Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | thyroid hormone receptor | 0.0475 | 1 | 1 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0475 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0475 | 1 | 1 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0224 | 0.4286 | 0.4214 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0475 | 1 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor | 0.0224 | 0.4286 | 0.4286 |
Brugia malayi | conserved hypotetical protein | 0.0224 | 0.4286 | 0.4214 |
Brugia malayi | nuclear hormone receptor | 0.0475 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0224 | 0.4286 | 0.4286 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0475 | 1 | 1 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0475 | 1 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0475 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0475 | 1 | 1 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0475 | 1 | 1 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0475 | 1 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0475 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0224 | 0.4286 | 0.4286 |
Loa Loa (eye worm) | hypothetical protein | 0.0251 | 0.4898 | 0.4898 |
Schistosoma mansoni | nuclear hormone receptor | 0.0224 | 0.4286 | 0.4163 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0475 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0224 | 0.4286 | 0.4214 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0475 | 1 | 1 |
Schistosoma mansoni | thyroid hormone receptor | 0.0475 | 1 | 1 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0475 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0475 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0475 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0224 | 0.4286 | 0.4286 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0475 | 1 | 1 |
Echinococcus granulosus | nuclear receptor subfamily 4 group A | 0.0224 | 0.4286 | 0.4214 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0475 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0224 | 0.4286 | 0.4286 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0475 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0224 | 0.4286 | 0.4286 |
Loa Loa (eye worm) | hypothetical protein | 0.0475 | 1 | 1 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0475 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0475 | 1 | 1 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0475 | 1 | 1 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0475 | 1 | 1 |
Schistosoma mansoni | nuclear hormone receptor superfamily protein-related | 0.0224 | 0.4286 | 0.4163 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0224 | 0.4286 | 0.4214 |
Brugia malayi | ecdysone receptor | 0.0224 | 0.4286 | 0.4214 |
Brugia malayi | nuclear receptor NHR-88 | 0.0224 | 0.4286 | 0.4214 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0475 | 1 | 1 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0475 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0475 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0224 | 0.4286 | 0.4286 |
Loa Loa (eye worm) | hypothetical protein | 0.0475 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0224 | 0.4286 | 0.4214 |
Loa Loa (eye worm) | hypothetical protein | 0.0251 | 0.4898 | 0.4898 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0251 | 0.4898 | 0.4833 |
Loa Loa (eye worm) | hypothetical protein | 0.0475 | 1 | 1 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0039 | 0.0062 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0224 | 0.4286 | 0.4286 |
Schistosoma mansoni | nuclear hormone receptor | 0.0224 | 0.4286 | 0.4163 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0251 | 0.4898 | 0.4788 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0475 | 1 | 1 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0475 | 1 | 1 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0475 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0251 | 0.4898 | 0.4833 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0475 | 1 | 1 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0475 | 1 | 1 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0475 | 1 | 1 |
Brugia malayi | nuclear hormone receptor family member odr-7 | 0.0224 | 0.4286 | 0.4214 |
Schistosoma mansoni | nuclear hormone receptor | 0.0475 | 1 | 1 |
Loa Loa (eye worm) | DR-78 | 0.0224 | 0.4286 | 0.4286 |
Brugia malayi | nuclear receptor NHR-88 | 0.0475 | 1 | 1 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0475 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0475 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0251 | 0.4898 | 0.4833 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0475 | 1 | 1 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0224 | 0.4286 | 0.4214 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0475 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0224 | 0.4286 | 0.4214 |
Loa Loa (eye worm) | hypothetical protein | 0.0475 | 1 | 1 |
Echinococcus granulosus | nuclear receptor nhr 48 | 0.0224 | 0.4286 | 0.4214 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0224 | 0.4286 | 0.4214 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0475 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0475 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0475 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0251 | 0.4898 | 0.4833 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0475 | 1 | 1 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0475 | 1 | 1 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0475 | 1 | 1 |
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.0224 | 0.4286 | 0.4286 |
Brugia malayi | nuclear receptor subfamily 1, group D, member 1, putative | 0.0224 | 0.4286 | 0.4214 |
Loa Loa (eye worm) | hypothetical protein | 0.0224 | 0.4286 | 0.4286 |
Brugia malayi | orphan nuclear receptor NR2E1 | 0.0224 | 0.4286 | 0.4214 |
Brugia malayi | nuclear receptor NHR-67 | 0.0224 | 0.4286 | 0.4214 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0224 | 0.4286 | 0.4214 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0475 | 1 | 1 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0224 | 0.4286 | 0.4214 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0475 | 1 | 1 |
Loa Loa (eye worm) | nuclear receptor NHR-67 | 0.0224 | 0.4286 | 0.4286 |
Brugia malayi | tailless protein | 0.0224 | 0.4286 | 0.4214 |
Brugia malayi | nuclear receptor RXR | 0.0224 | 0.4286 | 0.4214 |
Echinococcus multilocularis | nuclear receptor nhr 48 | 0.0224 | 0.4286 | 0.4214 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0475 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0224 | 0.4286 | 0.4286 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0251 | 0.4898 | 0.4833 |
Trichomonas vaginalis | voltage and ligand gated potassium channel, putative | 0.0039 | 0.0062 | 0.5 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0475 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0224 | 0.4286 | 0.4286 |
Schistosoma mansoni | coup transcription factor | 0.0475 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0251 | 0.4898 | 0.4898 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0475 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0251 | 0.4898 | 0.4898 |
Loa Loa (eye worm) | hypothetical protein | 0.0224 | 0.4286 | 0.4286 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0475 | 1 | 1 |
Loa Loa (eye worm) | voltage and ligand gated potassium channel | 0.0041 | 0.0124 | 0.0124 |
Schistosoma mansoni | nuclear receptor | 0.0224 | 0.4286 | 0.4163 |
Echinococcus granulosus | FTZ F1 alpha | 0.0475 | 1 | 1 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0475 | 1 | 1 |
Schistosoma mansoni | nuclear receptor nhr-48 | 0.0224 | 0.4286 | 0.4163 |
Brugia malayi | steroid hormone receptor | 0.0475 | 1 | 1 |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.0224 | 0.4286 | 0.4214 |
Schistosoma mansoni | hepatocyte nuclear factor 4-alpha (hnf-4-alpha) | 0.0224 | 0.4286 | 0.4163 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0475 | 1 | 1 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0475 | 1 | 1 |
Echinococcus multilocularis | nuclear receptor subfamily 4 group A | 0.0224 | 0.4286 | 0.4214 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0475 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0224 | 0.4286 | 0.4286 |
Loa Loa (eye worm) | hypothetical protein | 0.0251 | 0.4898 | 0.4898 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0251 | 0.4898 | 0.4788 |
Echinococcus granulosus | thyroid hormone receptor alpha | 0.0224 | 0.4286 | 0.4214 |
Schistosoma mansoni | nuclear receptor | 0.0224 | 0.4286 | 0.4163 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0475 | 1 | 1 |
Brugia malayi | hypothetical protein | 0.0251 | 0.4898 | 0.4833 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0475 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0224 | 0.4286 | 0.4286 |
Brugia malayi | nuclear hormone receptor | 0.0224 | 0.4286 | 0.4214 |
Brugia malayi | nuclear receptor RXR | 0.0251 | 0.4898 | 0.4833 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0475 | 1 | 1 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0475 | 1 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0251 | 0.4898 | 0.4898 |
Schistosoma mansoni | zinc finger protein | 0.0224 | 0.4286 | 0.4163 |
Onchocerca volvulus | 0.0475 | 1 | 1 | |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0475 | 1 | 1 |
Brugia malayi | nuclear hormone receptor family member nhr-6 | 0.0224 | 0.4286 | 0.4214 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0475 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0224 | 0.4286 | 0.4214 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.