Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.0344 | 0.0344 |
Schistosoma mansoni | vesicular acetylcholine transporter | 0.0233 | 1 | 1 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0049 | 0.1823 | 0.1823 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.0344 | 0.0344 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0033 | 0.1138 | 0.1138 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.1138 | 0.1138 |
Onchocerca volvulus | Huntingtin homolog | 0.012 | 0.4975 | 0.4975 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0015 | 0.0344 | 0.0344 |
Loa Loa (eye worm) | follicle stimulating hormone receptor | 0.0227 | 0.9707 | 0.9707 |
Echinococcus granulosus | GPCR family 2 | 0.0015 | 0.0344 | 0.0344 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0015 | 0.0344 | 0.0344 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.0344 | 0.0344 |
Echinococcus multilocularis | vesicular acetylcholine transporter | 0.0233 | 1 | 1 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0015 | 0.0344 | 0.0344 |
Loa Loa (eye worm) | vesicular acetylcholine transporter unc-17 | 0.0233 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.1138 | 0.1138 |
Echinococcus multilocularis | GPCR, family 2 | 0.0015 | 0.0344 | 0.0344 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0015 | 0.0344 | 0.0344 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.1823 | 0.1823 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0049 | 0.1823 | 0.1823 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0015 | 0.0344 | 0.0344 |
Brugia malayi | hypothetical protein | 0.012 | 0.4975 | 0.4975 |
Brugia malayi | follicle stimulating hormone receptor | 0.0227 | 0.9707 | 0.9707 |
Echinococcus granulosus | vesicular acetylcholine transporter | 0.0233 | 1 | 1 |
Onchocerca volvulus | Vesicular acetylcholine transporter homolog | 0.0233 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.0344 | 0.0344 |
Loa Loa (eye worm) | hypothetical protein | 0.012 | 0.4975 | 0.4975 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0015 | 0.0344 | 0.0344 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.0344 | 0.0344 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0015 | 0.0344 | 0.0344 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0049 | 0.1823 | 0.1823 |
Loa Loa (eye worm) | hypothetical protein | 0.012 | 0.4975 | 0.4975 |
Onchocerca volvulus | Huntingtin homolog | 0.012 | 0.4975 | 0.4975 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.